公开(公告)号：US20190275216A1

公开(公告)日：2019-09-12

申请号：US16346678

申请日：2017-11-21

申请人： Roche Diabetes Care, Inc.

发明人： Wilhelm Leichner ,  Hans List

IPC分类号： A61M1/00 ,  A61M5/148 ,  A61M5/14

摘要： The invention concerns a reservoir (1) for storing a liquid medicament. The reservoir (1) comprises a flexible container (10) which includes one folding layer (12), wherein the folding layer (12) includes a seam (13) which provides for a sealing of the flexible container (1). The reservoir comprises a rigid part (20) which is connected to the flexible container (10) and which includes a support (25) extending into the flexible container (10) and which includes one or more ports (21, 22) providing fluidic access to the flexible container (10). The reservoir comprises a porous hydrophilic membrane (26) which is connected to the support (25) of the rigid part (20). The invention further concerns a method for producing of a reservoir (1). The method comprises: providing a flexible tube (30) and a movable opening device (40) located inside the flexible tube (30), moving (S1) the moveable opening device (40) inside the flexible tube (30) by a distance in a longitudinal direction of the flexible tube (30), providing a rigid part (20), and bonding (S2) the flexible tube (30) to the rigid part (20) and providing a folding layer (12) included in the flexible container (10).

公开(公告)号：US10398831B2

公开(公告)日：2019-09-03

申请号：US14826804

申请日：2015-08-14

申请人： Roche Diabetes Care, Inc.

发明人： Ofer Yodfat ,  Avraham Neta ,  Yossi Shalev

IPC分类号： A61M5/142 ,  A61M5/172 ,  A61M5/145 ,  F04B43/12 ,  A61M5/148

摘要： Systems, methods and apparatuses for delivering therapeutic fluid to the body of a patient are disclosed. The apparatus includes a dispensing unit having a driving mechanism, a pumping mechanism, a reservoir containing therapeutic fluid, and an outlet port. The driving mechanism causes the pumping mechanism to positively displace therapeutic fluid within the reservoir for delivery of therapeutic fluid to the body of the patient via the outlet port.

公开(公告)号：US10363361B2

公开(公告)日：2019-07-30

申请号：US13524760

申请日：2012-06-15

申请人： Theo Arnitz

发明人： Theo Arnitz

IPC分类号： A61M5/172 ,  A61M5/142 ,  A61M5/145

摘要： A device for the dosed dispensing of a medium (e.g., therapeutic and/or diagnostic agent) for an insulin pump is proposed. The device comprises a transporting and transferring container, a measuring element, and an adjusting element for influencing a dispensing of the medium by way of a connection to an interior space. The transporting and transferring container has a reservoir for receiving the medium. The reservoir is closed by a displaceable element. The displaceable element is movably mounted in relation to the reservoir. A relative positioning of the displaceable element in relation to the reservoir determines the interior space of the reservoir available for receiving the medium. The measuring element senses the relative positioning of the displaceable element in relation to the reservoir. The measuring element and the adjusting element interact so that the dispensing of the medium is influenced by the relative positioning sensed by the measuring element.

公开(公告)号：US20190219534A1

公开(公告)日：2019-07-18

申请号：US16364340

申请日：2019-03-26

申请人： Roche Diabetes Care, Inc.

发明人： Scott E. Carpenter ,  Zheng Zheng Pan

IPC分类号： G01N27/327

CPC分类号： G01N27/3274 ,  G01N27/4163

摘要： Methods are disclosed for measuring an analyte concentration in a fluidic sample. Such methods allow one to correct and/or compensate for confounding variables such as hematocrit, salt concentration and/or temperature before providing an analyte concentration. The measurement methods use response information from a test sequence having at least one DC block, where DC block includes at least one excitation pulse and at least one recovery pulse, and where a closed circuit condition of an electrode system is maintained during the at least one recovery pulse. Information encoded in the excitation and recovery pulses are used to build within- and across-pulse descriptors to correct/compensate for hematocrit, salt concentration and/or temperature effects on the analyte concentration. Methods of transforming current response data also are disclosed. Further disclosed are devices, apparatuses and systems incorporating the various measurement methods.

公开(公告)号：USD852812S1

公开(公告)日：2019-07-02

申请号：US29593963

申请日：2017-02-14

申请人： Roche Diabetes Care, Inc.

设计人： Nils Babion ,  Mark Gilmore Mears

公开(公告)号：USD852811S1

公开(公告)日：2019-07-02

申请号：US29593962

申请日：2017-02-14

申请人： Roche Diabetes Care, Inc.

设计人： Nils Babion

公开(公告)号：US20190175828A1

公开(公告)日：2019-06-13

申请号：US16326752

申请日：2017-09-04

申请人： Roche Diabetes Care, Inc

发明人： Hans List ,  Frederic Wehowski

IPC分类号： A61M5/168 ,  A61M5/36

摘要： Disclosed is a supervision device (9) for supervising liquid drug flow in a flow channel (20). The supervision device (9) includes a flow detector (1), arranged for operatively coupling with the flow channel (20) and generating a flow detector signal in dependence of a flow in the flow channel (20) at a flow detection location. The supervision device (9) further includes a gas detector (8), arranged for operatively coupling with the flow channel (20) and generating a gas detector signal in dependence of whether liquid drug or gas is present in the flow channel (20) at a gas detection location at a distance upstream from the flow detection location. The supervision device (9) further includes a processing unit (90) in operative coupling with the flow detector (1) and the gas detector (8), wherein the processing unit (90) is configured to determine, based on a the gas detector signal, whether non-flowing liquid drug is present at the flow detection location or a gas bubble passes the flow detector if the flow detector signal does not indicate a liquid drug flow.

公开(公告)号：US10299737B2

公开(公告)日：2019-05-28

申请号：US12786993

申请日：2010-05-25

申请人： Matthias Essenpreis ,  Michael Schoemaker ,  Sebastiaan La Bastide ,  Derek Brandt ,  Theodor Koschinsky ,  Sascha Heckermann

发明人： Matthias Essenpreis ,  Michael Schoemaker ,  Sebastiaan La Bastide ,  Derek Brandt ,  Theodor Koschinsky ,  Sascha Heckermann

IPC分类号： A61B5/00 ,  G06F19/00 ,  A61B5/145

摘要： A method for diabetes care, the method (which also may be referred to as, involve or incorporate at least one of a tool, device or program) allowing for the characterization of the relevance of errors of parameters affecting glucose concentration on a postprandial glucose concentration outcome for a person with diabetes mellitusm, wherein the method involves at least one of sensing, determining, calculating, predicting, describing and communicating the effects of potential errors of parameters affecting glucose concentration on postprandial glucose concentration values within a clinically relevant glucose range.

公开(公告)号：US20190117135A1

公开(公告)日：2019-04-25

申请号：US16094510

申请日：2017-05-08

申请人： Roche Diabetes Care, Inc.

发明人： Herbert Wieder

IPC分类号： A61B5/145 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/00

摘要： Disclosed is a method for initializing an analyte measurement system (1, 2, 3), the analyte measurement system (1, 2, 3) being designed for continuous in-vivo measurement of a body fluid analyte concentration. The method including the steps of: a) providing the analyte measurement system (1, 2, 3,) with a control device (3) and a separate skin-mountable patch device (1, 2), the patch device (1, 2) including a disposable unit (1) and an electronics unit (2), the disposable unit (1) including a transcutaneous analyte sensor (10) and machine-readable sensor identifier (121), the electronics unit (2) being configured to releasable couple for an application time period to the disposable unit (1); b) providing a number of stored initialization data sets in a remote database system (4), each stored initialization data set comprising initialization data for an analyte sensor batch; c) reading, via a reading device (31) of the control device (3), the sensor identifier from the disposable unit (1) into the control device (3) and transmitting the sensor identifier to the remote database system; d) determining a matching initialization data set, the matching initialization data set being a stored initialization data set that matches the sensor identifier; e) transmitting the matching initialization data set from the remote database system to the control device (3); f) transmitting the matching initialization data set to the electronics unit (2) and storing the matching initialization data set in a memory (21) of the electronics unit (2).

公开(公告)号：US10260085B2

公开(公告)日：2019-04-16

申请号：US13524199

申请日：2012-06-15

申请人： Carina Horn ,  Dieter Heindl ,  Hans-Peter Haar ,  Nelli Steinke

发明人： Carina Horn ,  Dieter Heindl ,  Hans-Peter Haar ,  Nelli Steinke

IPC分类号： C12Q1/54

摘要： In one form, a diagnostic element for determining at least one analyte is provided. In a further form, an analytical measuring device includes the diagnostic element. Still, other forms are related to methods for the determination of an analyte, correcting a signal generated by an analyte, and/or checking the detection optics of an analytical measuring device using the diagnostic element. Another form is related to a system for the controlled release of a reagent and the use of such a system as a circuit element. Other aspects include, but are not limited to, unique methods, techniques, products, systems and devices involving diagnostic elements.