公开(公告)号：US20230390063A1

公开(公告)日：2023-12-07

申请号：US18454237

申请日：2023-08-23

Applicant: EDWARDS LIFESCIENCES CORPORATION

Inventor： Brian S. Conklin

IPC: A61F2/24

CPC classification number: A61F2/2487 ,  A61F2002/249 ,  A61F2220/0008 ,  A61F2220/0075

Abstract: Systems, apparatuses, and methods disclosed herein are provided for medical treatment, including treatment of dilated hearts (e.g., dilated left ventricle) or functional mitral valve regurgitation within a human heart. In instances, transcatheter medical treatments may be utilized. The portion of the patient's heart may be dilated due to a myocardial infarction or other cardiomyopathy. The treatment may comprise beating-heart repair of left ventricles with ischemic or non-ischemic dilated cardiomyopathy. The treatments may include approximating papillary muscles of the heart.

公开(公告)号：US20230165681A1

公开(公告)日：2023-06-01

申请号：US18159982

申请日：2023-01-26

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Amy E. Munnelly ,  Milton Deherrera

IPC: A61F2/24

CPC classification number: A61F2/2448 ,  A61F2/2466 ,  A61F2250/0004

Abstract: An annuloplasty ring for repair of mitral and tricuspid valves that can be shape adjusted once installed to fine-tune the shape and correct for small errors in the inherently imprecise sizing process. The ring has an adjustable 3D ring core of malleable metal that can be reshaped in real-time during the procedure before or after the patient is weaned off-pump by applying simple displacements to a cable and housing arrangement. The shape of the annuloplasty ring is adjusted incrementally in steps until an optimum level of regurgitation reduction is attained. Once the surgeon is satisfied with the result, the delivery system can be can easily detached from the implant and removed. The thickness of the core could be continuously variable to control how and where deformation occurs. The ring may also incorporate an expansion joint to enable a subsequent valve-in-ring procedure.

公开(公告)号：US11337805B2

公开(公告)日：2022-05-24

申请号：US16252140

申请日：2019-01-18

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin

IPC: A61F2/24

Abstract: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, such as a handle that prevents implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate temporary deformation of a nitinol prosthetic valve to pass between adjacent ribs of a patient without rib spreading. Valves are provided having a wireform and stiffener band made of materials that exhibit superelastic properties. Valve holders, introducers, and valves according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.

公开(公告)号：USD933229S1

公开(公告)日：2021-10-12

申请号：US29645199

申请日：2018-04-24

Applicant: Edwards Lifesciences Corporation

Designer： Brian S. Conklin ,  Derrick Johnson

公开(公告)号：US20210244540A1

公开(公告)日：2021-08-12

申请号：US17244771

申请日：2021-04-29

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Louis A. Campbell

IPC: A61F2/24

Abstract: An annuloplasty ring assembly with detachable handle includes an annuloplasty ring configured to be secured to an annulus of a heart valve and an annuloplasty ring. The annuloplasty ring is attached to the ring holder such that the annuloplasty ring is in conformal contact along a lower surface of a peripheral edge portion of the ring holder. The assembly includes a handle adapter extending proximally from an upper proximal face of the ring holder. The handle adapter is also attached or attachable to a distal attachment end of the handle on one side and removably attached to the annuloplasty ring holder on another side.

公开(公告)号：US20200345491A1

公开(公告)日：2020-11-05

申请号：US16936364

申请日：2020-07-22

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Derrick Johnson

IPC: A61F2/24 ,  A61B17/00

Abstract: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are in various embodiments configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, such as a removable activator dial and a removable handle that prevent implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate passing of a prosthetic valve between adjacent ribs of a patient. Valve holders and introducers according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.

公开(公告)号：US10799353B2

公开(公告)日：2020-10-13

申请号：US15963311

申请日：2018-04-26

Applicant: Edwards Lifesciences Corporation

Inventor： Ankita Bordoloi Gurunath ,  Derrick Johnson ,  Brian S. Conklin ,  Myron Howanec, Jr.

IPC: A61F2/24 ,  A61M25/00

Abstract: A prosthetic heart valve holder system includes a prosthetic heart valve having a base at an inflow end, a plurality of commissure posts extending from the base toward an outflow end, and valve leaflets secured to the commissure posts to permit flow through the heart valve. A deflector is provided at the outflow end having a central hub and a plurality of arms extending from the central hub secured to and covering the tips of respective commissure posts. A valve support body is secured to the base and a post connects the valve support body to the hub of the deflector. The plurality of arms are sufficiently collapsible such that, in a first position, free ends of the arms are located axially between the hub and the valve support body to prevent suture looping during an implant procedure, and in a second position, the hub is located axially between the free ends of the arms and the valve support body to permit removal of the deflector from the outflow side of the valve, through the valve leaflets, to the inflow side of the valve.

公开(公告)号：USD893031S1

公开(公告)日：2020-08-11

申请号：US29713540

申请日：2019-11-15

Applicant: Edwards Lifesciences Corporation

Designer： Da-Yu Chang ,  Brian S. Conklin

公开(公告)号：US20200093593A1

公开(公告)日：2020-03-26

申请号：US16695008

申请日：2019-11-25

Applicant: Edwards Lifesciences Corporation

Inventor： Visith Chung ,  Da-Yu Chang ,  Brian S. Conklin ,  Grace Myong Kim ,  Louis A. Campbell ,  Donald E. Bobo, JR. ,  Myron Howanec ,  David S. Lin ,  Peng Norasing ,  Francis M. Tran ,  Mark Van Nest ,  Thomas Chien ,  Harvey H. Chen ,  Isidro L. Guerrero ,  Derrick Johnson ,  Paul A. Schmidt

IPC: A61F2/24

Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

公开(公告)号：US20200069221A1

公开(公告)日：2020-03-05

申请号：US16586807

申请日：2019-09-27

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Da-Yu Chang

IPC: A61B5/107 ,  A61B5/00 ,  A61B5/02 ,  A61F2/24

Abstract: A valve sizer for determining an appropriate replacement valve size when performing a heart valve replacement procedure is provided. In one version the valve sizer has a hollow shaft with proximal and distal ends. A movable sizing element couples to the distal end of the shaft and is radially expandable between first, contracted and second, expanded positions. An actuator assembly on a handle includes an actuator coupled to a clutch member via a ball-spring-detent clutch. A rod extends through the shaft and maintains a fixed distance between the handle and a distal hub in the sizing element. Movement of the actuator causes axial movement of the shaft, thereby causing radial expansion of sizing petals relative to the hub. The clutch slips when a predetermined reaction force from the surrounding valve annulus is met by the petals.