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公开(公告)号:US20110121428A1
公开(公告)日:2011-05-26
申请号:US12622625
申请日:2009-11-20
申请人: Xin Lin , Daniel J. Blomberg , Jiang-Kai Zuo
发明人: Xin Lin , Daniel J. Blomberg , Jiang-Kai Zuo
IPC分类号: H01L29/73 , H01L21/331
CPC分类号: H01L29/66272 , H01L21/8249 , H01L27/0623 , H01L29/0804 , H01L29/1004 , H01L29/7322
摘要: An improved bipolar transistor (40, 40′) is provided, manufacturable by a CMOS IC process without added steps. The improved transistor (40, 40′) comprises an emitter (48) having first (482) and second (484) portions of different depths (4821, 4841), a base (46) underlying the emitter (48) having a central portion (462) of a first base width (4623) underlying the first portion (482) of the emitter (48), a peripheral portion (464) having a second base width (4643) larger than the first base width (4623) partly underlying the second portion (484) of the emitter (48), and a transition zone (466) of a third base width (4644) and lateral extent (4661) lying laterally between the first (462) and second (464) portions of the base (46), and a collector (44) underlying the base (46). The gain of the transistor (40, 40′) is much larger than a conventional bipolar transistor (20) made using the same CMOS process. By adjusting the lateral extent (4661) of the transition zone (466), the properties of the improved transistor (40, 40′) can be tailored to suit different applications without modifying the underlying CMOS IC process.
摘要翻译: 提供改进的双极晶体管(40,40'),可通过CMOS IC工艺制造而无需附加步骤。 改进的晶体管(40,40')包括具有不同深度(4821,4481)的第一(482)和第二(484)部分的发射器(48),位于发射器(48)下方的基座(46)具有中心部分 (462)位于发射器(48)的第一部分(482)下方的第一基底宽度(4623)的外围部分(462),具有大于第一基部宽度(4623)的第二基底宽度(4643)的周边部分(464) 发射器(48)的第二部分(484)和位于第一(462)和第二(464)部分之间的侧向位于第三基部宽度(4644)和横向范围(4661)的过渡区(466) 基部(46)和底部(46)下方的收集器(44)。 晶体管(40,40')的增益比使用相同CMOS工艺制造的传统双极晶体管(20)大得多。 通过调整过渡区域(466)的横向范围(4661),改进的晶体管(40,40')的特性可以被调整以适应不同的应用而不修改底层的CMOS IC工艺。
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公开(公告)号:US20110089500A1
公开(公告)日:2011-04-21
申请号:US12975808
申请日:2010-12-22
申请人: Hongning Yang , Xin Lin , Jiang-Kai Zuo
发明人: Hongning Yang , Xin Lin , Jiang-Kai Zuo
IPC分类号: H01L29/772
CPC分类号: H01L29/66484 , H01L29/1041 , H01L29/7831 , H01L29/7833
摘要: A semiconductor device includes a substrate, a source region formed over the substrate, a drain region formed over the substrate, a first gate electrode over the substrate adjacent to the source region and between the source and drain regions, and a second gate electrode over the substrate adjacent to the drain region and between the source and drain regions.
摘要翻译: 半导体器件包括衬底,形成在衬底上的源极区域,形成在衬底上的漏极区域,与源极区域相邻并且在源极和漏极区域之间的衬底上的第一栅电极,以及位于源极和漏极区域之间的第二栅电极 衬底,其与漏极区域相邻并且在源极和漏极区域之间。
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103.
公开(公告)号:US06265538B1
公开(公告)日:2001-07-24
申请号:US09257703
申请日:1999-02-25
申请人: Warner C. Greene , Xin Lin , Romas Gelezuinas
发明人: Warner C. Greene , Xin Lin , Romas Gelezuinas
IPC分类号: A61K3800
CPC分类号: C12N9/1205
摘要: The present invention provides the molecular basis for cytokine induction of NF-&kgr;B-dependent immune and inflammatory responses, emphasizing a role for both NIK-NIK and NIK-IKK protein-protein interactions. A relatively small region of NIK selectively impairs the NIK-IKK interaction. The present invention provides a highly specific method for modulating NF-&kgr;B-dependent immune, inflammatory, and anti-apoptotic responses, based on interruption of the critical protein-protein interaction of NIK and IKK. The present invention provides methods for inhibiting NF-&kgr;B-dependent gene expression, using mutant NIK proteins. One embodiment of the present invention provides kinase-deficient NIK mutant proteins that inhibit activation of IKK. Another embodiment of the invention provides N-terminus NIK mutant proteins that bind IKK, thus inhibiting NIK/IKK interaction.
摘要翻译: 本发明提供NF-κB依赖性免疫和炎症反应的细胞因子诱导的分子基础,强调NIK-NIK和NIK-IKK蛋白质 - 蛋白质相互作用的作用。 NIK相对较小的区域选择性地损害NIK-IKK相互作用。 本发明基于NIK和IKK的关键蛋白质 - 蛋白质相互作用的中断,提供了调节NF-κB依赖性免疫,炎症和抗凋亡反应的高度特异性方法。 本发明提供使用突变NIK蛋白抑制NF-κB依赖性基因表达的方法。 本发明的一个实施方案提供抑制IKK活化的激酶缺陷型NIK突变蛋白。 本发明的另一个实施方案提供结合IKK的N末端NIK突变蛋白,从而抑制NIK / IKK相互作用。
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