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公开(公告)号：US11235161B2
公开(公告)日：2022-02-01
申请号：US16583591
申请日：2019-09-26
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
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公开(公告)号：US20210361219A1
公开(公告)日：2021-11-25
申请号：US17320778
申请日：2021-05-14
Applicant: Medtronic, Inc.
Inventor： Trent Fischer , Karen Kleckner , Daniel S. Flo , Marc C. Steckler , Subham Ghosh
Abstract: Electrical activity from tissue of a patient is monitored using a plurality of external electrodes to generate a plurality of electrical signals over time. The plurality of electrical signals are filtered using a first filter having a first frequency range to generate a plurality of first filtered signals. The plurality of electrical signals are filtered using a second filter having a second frequency range different than the first frequency range to generate a plurality of second filtered signals. At least one QRS complex is detected based on the plurality of first filtered signals. A QRS peak of the at least one QRS complex is detected based on the plurality of second filtered signals and the detected at least one QRS complex.
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公开(公告)号：US20210236038A1
公开(公告)日：2021-08-05
申请号：US17143474
申请日：2021-01-07
Applicant: Medtronic, Inc.
Inventor： Brandon K. Hoglund , Karen J. Kleckner , Marc C. Steckler , Trent M. Fischer , Subham Ghosh , Irah-Vanesa H. Comia
Abstract: Systems and methods are described herein for detecting disturbances in cardiac signals. An electrode apparatus includes a plurality of external electrodes to be disposed proximate a patient's skin. A computing apparatus includes processing circuitry. The computing apparatus is operably coupled to the electrode apparatus. The computing apparatus is configured to monitor electrical activity from tissue of a patient using a plurality of external electrodes to generate a plurality of electrical signals. At least one of the electrical signals of the plurality of electrical signals is filtered. At least one disturbance in the at least one electrical signal is detected using the at least one filtered signal. A temporal location of the at least one disturbance in the at least one electrical signal is determined based on a time that the at least one filtered signal crosses a predetermined threshold.
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公开(公告)号：US20210060348A1
公开(公告)日：2021-03-04
申请号：US17001627
申请日：2020-08-24
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: A method includes determining whether electrical activity is indicative of atrial fibrillation, determining whether mechanical activity is indicative of atrial fibrillation, and adjusting a pacing parameter or mode based on whether the electrical activity and the mechanical activity are indicative of atrial fibrillation. The electrical activity may be detected based on a far-field measurement. The method may be performed using a leadless implantable medical device.
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公开(公告)号：US10799703B2
公开(公告)日：2020-10-13
申请号：US15853102
申请日：2017-12-22
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh , Zhongping Yang
Abstract: Cardiac electrical heterogeneity information may be used to determine whether one or more His bundle paced settings for His bundle pacing therapy are acceptable for His bundle pacing. Cardiac electrical heterogeneity information may be generated during His bundle pacing, and the evaluation against baseline information and/or other information to determine whether the His bundle paced settings are acceptable.
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Patent Agency Ranking
公开(公告)号：US20200094061A1
公开(公告)日：2020-03-26
申请号：US16583591
申请日：2019-09-26
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: Ventricle-from-atrium (VfA) cardiac therapy may utilize a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The exemplary devices and methods may determine whether the tissue-piercing electrode is achieving effective left ventricular capture. Additionally, one or more pacing parameters, or paced settings, may be adjusted in view of the effective left ventricular capture determination.
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公开(公告)号：US20200069949A1
公开(公告)日：2020-03-05
申请号：US16557143
申请日：2019-08-30
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
IPC: A61N1/365 , A61N1/05 , A61B5/0472 , A61B5/11
Abstract: VfA cardiac therapy uses an implantable medical device or system. The implantable medical device includes a tissue-piercing electrode implanted in the left ventricular myocardium of the patient's heart from the right atrium through the right atrial endocardium and central fibrous body. The device may include a right atrial electrode, a right atrial motion detector, or both. The device may be implanted completely within the patient's heart or may use one or more leads to implant electrodes in the patient's heart. A separate medical device may be used to provide some functionality for cardiac therapy. The implantable medical device or separate medical device may be used to measure physiological response information, such as cardiac electrical heterogeneity information. The physiological response information may be used to calibrate and deliver adaptive pacing therapy.
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公开(公告)号：US10561847B2
公开(公告)日：2020-02-18
申请号：US15906238
申请日：2018-02-27
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
IPC: A61N1/00 , A61N1/37 , A61N1/02 , A61N1/365 , A61N1/375 , A61N1/372 , A61B5/00 , A61B5/044 , A61B5/0452 , A61B5/042
Abstract: Capture management in a left ventricular leadless pacing device that includes determining an intrinsic P-wave of a sensed cardiac signal, sensing an electromechanical signal from an electromechanical sensor of the pacing device, and determining an intrinsic electromechanical atrioventricular interval of the sensed electromechanical signal in response to the sensed P-wave. Ventricular pacing is delivered via the one or more electrodes of the pacing device, and a ventricular pacing (V-pace) event is determined in response to the delivered ventricular pacing, and a V-pace to electromechanical response interval is determined in response to the V-pace event. A determination as to capture is detected is made in response to the intrinsic electromechanical atrioventricular interval and the V-pace to electromechanical response interval, and a pacing parameter is determined in response to determining whether capture is detected.
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公开(公告)号：US20190269926A1
公开(公告)日：2019-09-05
申请号：US15909603
申请日：2018-03-01
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: A method and system for delivering cardiac pacing therapy that includes sensing electrical activity of tissue of a patient from a plurality of external electrodes during delivery of a non-ambulatory pacing therapy from a pacing device and determining an optimal electromechanical (EM) response time from an optimal electrical activation determined from electrical heterogeneity information obtained during non-ambulatory pacing therapy. During delivery of subsequent ambulatory pacing, the pacing sensing an EM signal from an EM sensor of the pacing device, determines a current EM response time in response to the sensed EM signal, and adjusting a pacing parameter setting of the ambulatory pacing therapy in response to comparing the current EM response time to the optimal EM response time.
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公开(公告)号：US20190262619A1
公开(公告)日：2019-08-29
申请号：US15906238
申请日：2018-02-27
Applicant: Medtronic, Inc.
Inventor： Subham Ghosh
Abstract: Capture management in a left ventricular leadless pacing device that includes determining an intrinsic P-wave of a sensed cardiac signal, sensing an electromechanical signal from an electromechanical sensor of the pacing device, and determining an intrinsic electromechanical atrioventricular interval of the sensed electromechanical signal in response to the sensed P-wave. Ventricular pacing is delivered via the one or more electrodes of the pacing device, and a ventricular pacing (V-pace) event is determined in response to the delivered ventricular pacing, and a V-pace to electromechanical response interval is determined in response to the V-pace event. A determination as to capture is detected is made in response to the intrinsic electromechanical atrioventricular interval and the V-pace to electromechanical response interval, and a pacing parameter is determined in response to determining whether capture is detected.
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