公开(公告)号：US20050032037A1

公开(公告)日：2005-02-10

申请号：US10492188

申请日：2002-10-07

Applicant: Megan Ash ,  David Edwards ,  Aaron Gibbeson ,  Dianne Kerr ,  Lisa Moncur ,  Philip Myers

Inventor： Megan Ash ,  David Edwards ,  Aaron Gibbeson ,  Dianne Kerr ,  Lisa Moncur ,  Philip Myers

IPC: G01N33/543 ,  G01N33/569 ,  C12Q1/70 ,  C12M1/34 ,  G01N33/554

CPC classification number: G01N33/569 ,  G01N33/54386 ,  G01N33/56911 ,  G01N33/56916 ,  G01N2035/00108 ,  Y10S435/805 ,  Y10S436/807 ,  Y10T436/25125

Abstract: A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines means for protecting the binding partner from being dislodged or scraped off the solid support by physical means. The provision of protection against the binding partner being dislodged from or scraped off the solid support improves the reliability of tests such as immunoassays being conducted with the solid support and also enables such tests to be automated. Modules and machines for use with the solid support, and the automated conduct of tests ate also disclosed.

Abstract translation: 公开了一种用于检测目标微生物或试剂的系统和装置，其涉及携带特异性的特定微生物或试剂的结合配偶体的固体支持物，其特征在于，其定义了用于保护结合配偶体的装置 通过物理手段驱除或刮掉固体支持物。 提供对绑定伙伴的保护以抵消或刮除固体支持物提高了测试的可靠性，例如用固体支持物进行的免疫测定，并且还使得能够自动化这些测试。 用于固体支持的模块和机器，以及测试的自动化进行了披露。

公开(公告)号：US20050008633A1

公开(公告)日：2005-01-13

申请号：US10843693

申请日：2004-05-11

Applicant: Rita Vanbever ,  David Edwards

Inventor： Rita Vanbever ,  David Edwards

IPC: A61K31/66 ,  A61K38/00 ,  A61K38/22 ,  A61K38/28 ,  A61K39/395 ,  A61K45/06

CPC classification number: A61K45/06 ,  A61K31/66 ,  A61K38/24 ,  A61K38/27 ,  A61K38/28 ,  A61K39/395 ,  A61K2300/00

Abstract: The present invention is drawn to methods of enhancing bioavailability, pulmonary absorption and/or optimal dosing of a biologically active agent. The methods of the invention enhance the pulmonary absorption and bioavailability of a biologically active agent by administering to the pulmonary system of a subject, a biologically active agent and a macrophage inhibiting agent that is suitable for administration to a subject's pulmonary system.

Abstract translation: 本发明涉及提高生物活性剂的生物利用度，肺吸收和/或最佳给药的方法。 本发明的方法通过向受试者的肺系统施用适于给予受试者的肺部系统的生物活性剂和巨噬细胞抑制剂来增强生物活性剂的肺吸收和生物利用度。