公开(公告)号：US11571299B2

公开(公告)日：2023-02-07

申请号：US16921901

申请日：2020-07-06

Applicant: Edwards Lifesciences Corporation

Inventor： Hengchu Cao ,  Brian S. Conklin ,  Paul A. Schmidt ,  Grace Myong Kim ,  James A. Davidson ,  Hoa Trinh Tran ,  Kristy Luong Tam

IPC: A61F2/24

Abstract: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.

公开(公告)号：US11554012B2

公开(公告)日：2023-01-17

申请号：US17806928

申请日：2022-06-14

Applicant: Edwards Lifesciences Corporation

Inventor： Da-Yu Chang ,  Amy E. Munnelly ,  Van Huynh ,  Avina Gupta ,  Brian S. Conklin ,  Sooji Van Echten ,  Kurt Kelly Reed ,  Amanda Grace Sall

IPC: A61F2/24

Abstract: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.

公开(公告)号：US11471275B2

公开(公告)日：2022-10-18

申请号：US16888649

申请日：2020-05-29

Applicant: Edwards Lifesciences Corporation

Inventor： Salvador Marquez ,  Da-Yu Chang ,  Cindy Woo ,  Hao-Chung Yang ,  Lynn T. Dang ,  Javier A. Sanguinetti ,  Alexander H. Siemons ,  Yaron Keidar ,  Virginia Qi Lin ,  Brian S. Conklin ,  Donald E. Bobo, Jr.

IPC: A61F2/24 ,  A61B5/026 ,  A61B5/00

Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.

公开(公告)号：US20220313429A1

公开(公告)日：2022-10-06

申请号：US17806928

申请日：2022-06-14

Applicant: Edwards Lifesciences Corporation

Inventor： Da-Yu Chang ,  Amy E. Munnelly ,  Van Huynh ,  Avina Gupta ,  Brian S. Conklin ,  Sooji Van Echten ,  Kurt Kelly Reed ,  Amanda Grace Sall

IPC: A61F2/24

Abstract: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.

公开(公告)号：US11376125B2

公开(公告)日：2022-07-05

申请号：US16673487

申请日：2019-11-04

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  Michael C. Murad

IPC: A61F2/24

Abstract: A valve holder for delivering a prosthetic heart valve to an implant site is in various embodiments configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. The valve holder can be configured to deploy or actuate automatically when performing preparatory steps that are already familiar to practitioners, such as attaching a delivery handle to the valve holder, so that the valve holders will not require additional steps or training to use. Therefore, operation of the valve holders is kept simple, and occurrences of mistakes caused by user error can be minimized or reduced. Valve holders according to different embodiments can be designed to accommodate implantation of prosthetic heart valves from either the inflow end or the outflow end of the native valve annulus.

公开(公告)号：USD952143S1

公开(公告)日：2022-05-17

申请号：US29797632

申请日：2021-07-01

Applicant: Edwards Lifesciences Corporation

Designer： Brian S. Conklin

公开(公告)号：US20220110743A1

公开(公告)日：2022-04-14

申请号：US17645690

申请日：2021-12-22

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.

公开(公告)号：US11207178B2

公开(公告)日：2021-12-28

申请号：US16989826

申请日：2020-08-10

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin

IPC: A61F2/24

Abstract: A prosthetic heart valve can include a valve frame having a wireform portion and a stent portion. The wireform and stent portions can be undetachably coupled together via a plurality of upright struts so as to form a one-piece prosthetic heart valve frame. Alternatively, a self-expanding wireform portion and a balloon-expandable stent portion can be coupled together via one or more leaflets and a subassembly having a flexible leaflet support stent and a sealing ring. The wireform portion can include cusps and commissures configured to support a plurality of leaflets. The prosthetic valve can be radially collapsible for minimally invasive and/or transcatheter delivery techniques. Disclosed embodiments can also provide flexion of the wireform portion (e.g., of the commissures) in response to physiologic pulsatile loading when the valve is implanted in a patient's native valve annulus. Methods of making and using prosthetic heart valves are also disclosed.

公开(公告)号：US20210369277A1

公开(公告)日：2021-12-02

申请号：US17404931

申请日：2021-08-17

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  James A. Davidson ,  Ralph Schneider

IPC: A61B17/10 ,  A61B17/068 ,  A61B17/064 ,  A61B17/122 ,  A61B17/128

Abstract: Devices and methods for deploying self-cinching surgical clips. A device can access at least two layers of tissue or material from only one side of the tissue or material and puncture through the two layers of tissue or material. The various configurations of clips disclosed herein can be made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip can be disposed within the housing of the delivery device and held in a constrained state until deployment wherein the clip assumes its relaxed state, where the ends of the clip can be brought into close approximation, thereby securing the layers of tissue or material together.

公开(公告)号：US11090053B2

公开(公告)日：2021-08-17

申请号：US16356604

申请日：2019-03-18

Applicant: Edwards Lifesciences Corporation

Inventor： Brian S. Conklin ,  James A. Davidson ,  Ralph Schneider

IPC: A61B17/10 ,  A61B17/068 ,  A61B17/064 ,  A61B17/122 ,  A61B17/128

Abstract: Devices and methods for deploying self-cinching surgical clips. A device can access at least two layers of tissue or material from only one side of the tissue or material and puncture through the two layers of tissue or material. The various configurations of clips disclosed herein can be made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip can be disposed within the housing of the delivery device and held in a constrained state until deployment wherein the clip assumes its relaxed state, where the ends of the clip can be brought into close approximation, thereby securing the layers of tissue or material together.