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公开(公告)号：US10667904B2
公开(公告)日：2020-06-02
申请号：US15452617
申请日：2017-03-07
发明人： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, Jr.
摘要： Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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公开(公告)号：US20230016821A1
公开(公告)日：2023-01-19
申请号：US17935546
申请日：2022-09-26
IPC分类号： A61F2/24
摘要： A tension-distribution device includes a rotationally-symmetric structure and two or more suture-engagement features associated with the rotationally-symmetric structure, the suture-engagement features being configured to receive one or more suture portions therein. The two or more suture-engagement features are evenly spaced rotationally about an axial center of the rotationally-symmetric structure.
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公开(公告)号：US20230068893A1
公开(公告)日：2023-03-02
申请号：US18046473
申请日：2022-10-13
发明人： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, Jr.
摘要： Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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公开(公告)号：US11786374B2
公开(公告)日：2023-10-17
申请号：US17156455
申请日：2021-01-22
发明人： Salvador Marquez , Lynn T. Dang , Javier A. Sanguinetti , Emily Cheng Zhou , Gary Alan Breitbach
CPC分类号： A61F2/2472 , A61F2/76 , F16K37/0091 , A61F2/2418 , A61F2002/7635
摘要： A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.
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公开(公告)号：US20210137682A1
公开(公告)日：2021-05-13
申请号：US17156455
申请日：2021-01-22
发明人： Salvador Marquez , Lynn T. Dang , Javier A. Sanguinetti , Emily Cheng Zhou , Gary Alan Breitbach
摘要： A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.
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公开(公告)号：US20230414359A1
公开(公告)日：2023-12-28
申请号：US18465920
申请日：2023-09-12
发明人： Salvador Marquez , Lynn T. Dang , Javier A. Sanguinetti , Emily Cheng Zhou , Gary Alan Breitbach
CPC分类号： A61F2/2472 , A61F2/76 , F16K37/0091 , A61F2/2418 , A61F2002/7635
摘要： A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.
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公开(公告)号：US11471275B2
公开(公告)日：2022-10-18
申请号：US16888649
申请日：2020-05-29
发明人： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, Jr.
摘要： Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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公开(公告)号：US20210401418A1
公开(公告)日：2021-12-30
申请号：US17469784
申请日：2021-09-08
IPC分类号： A61B17/00 , A61B5/00 , A61B5/0205
摘要： Disclosed herein are left atrial appendage (LAA) occluders that include self-powered physiological sensors to monitor physiological parameters of a subject. The sensors can be powered by harvesting energy generated by the patient's body or using wireless power delivery technologies. The disclosed devices can be used to close the LAA and to provide self-powering sensors to wirelessly monitor physiological parameters such as heart rate, pressure, temperature, size of the atrium, and levels of biomarkers such as C-reactive protein (CRP) and B-type natriuretic peptide (BNP) (e.g., using biosensors). In addition to addressing the stroke risk for patients with non-valvular atrial fibrillation, the disclosed devices offer post-surgical connected care that can reduce hospital readmissions, provide superior medical management, and improve patient quality of life.
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公开(公告)号：US10898329B2
公开(公告)日：2021-01-26
申请号：US16257982
申请日：2019-01-25
发明人： Salvador Marquez , Lynn T. Dang , Javier A. Sanguinetti , Emily Cheng Zhou , Gary Alan Breitbach
摘要： A testing apparatus is disclosed herein for testing properties of a prosthetic device. The testing apparatus may comprise a dual-drive pulsatile flow tester with the ability to determine coaptation of valve leaflets of a prosthetic device. The testing apparatus may be able to test prosthetic heart valves and reproduce physiological conditions of a prosthetic heart valve.
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公开(公告)号：US20200289257A1
公开(公告)日：2020-09-17
申请号：US16888649
申请日：2020-05-29
发明人： Salvador Marquez , Da-Yu Chang , Cindy Woo , Hao-Chung Yang , Lynn T. Dang , Javier A. Sanguinetti , Alexander H. Siemons , Yaron Keidar , Virginia Qi Lin , Brian S. Conklin , Donald E. Bobo, JR.
摘要： Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.
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