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171.发明申请Novel methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells 有权用于血管生成祖细胞的体外鉴定，分离和分化的新方法公开(公告)号：US20030194802A1
公开(公告)日：2003-10-16
申请号：US10211522
申请日：2002-08-05
Inventor： Joseph Itskovitz-Eldor , Sharon Gerecht-Nir
IPC: A61K048/00 , C12N005/08
CPC classification number: C12N5/0692 , A61K35/12 , C12N2506/02
Abstract: There is provided a simplified and inexpensive method for the in-vitro identification, isolation and culture of human vasculogenic progenitor cells. The method and the progenitor cells isolated thereby can be used for in-vitro vascular engineering, treatment of congenital and acquired vascular and hematological abnormalities, for evaluation and development of drugs affecting vasculo- and angiogenic processes, and for further investigation into tissue differentiation and development.
Abstract translation: 提供了用于体外鉴定，分离和培养人类血管生成祖细胞的简化和便宜的方法。 由此分离的方法和祖细胞可用于体外血管工程，治疗先天性和获得性血管和血液异常，用于评估和开发影响血管和血管生成过程的药物，并进一步研究组织分化和发育 。
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172.发明申请Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer 审中-公开用于免疫欺骗的方法和药物组合物，特别可用于治疗癌症公开(公告)号：US20030017134A1
公开(公告)日：2003-01-23
申请号：US10108511
申请日：2002-03-29
Inventor： Yoram Reiter , Avital Lev
IPC: A61K039/395
CPC classification number: C07K14/70539 , A61K2039/505 , C07K16/2866 , C07K16/30 , C07K2317/624 , C07K2319/00
Abstract: An immuno-molecule which comprises a soluble human MHC class I effector domain; and an antibody targeting domain which is linked to the soluble human MHC class I effector domain, methods of making same and uses thereof.
Abstract translation: 包含可溶性人MHC I类效应结构域的免疫分子; 和与可溶性人MHC I类效应结构域连接的抗体靶向结构域，其制备方法和用途。
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公开(公告)号：US20030003535A1
公开(公告)日：2003-01-02
申请号：US10073300
申请日：2002-02-13
Inventor： Yoram Reiter
IPC: C07K014/74 , C07H021/04 , C12P021/02 , C12N005/06
CPC classification number: C07K14/70539
Abstract: A recombinant polypeptide and nucleic acid constructs capable of expressing the recombinant polypeptide are provided. The recombinant polypeptide comprises a chimeric polypeptide including an antigenic peptide being capable of binding a human MHC class I, a functional human null-2 microglobulin and a functional human MHC class I heavy chain.
Abstract translation: 提供能够表达重组多肽的重组多肽和核酸构建体。 重组多肽包含嵌合多肽，其包括能够结合人MHC I类，功能性人β-2微球蛋白和功能性人MHC I类重链的抗原肽。
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