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1.发明申请Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer 审中-公开用于免疫欺骗的方法和药物组合物，特别可用于治疗癌症公开(公告)号：US20030017134A1
公开(公告)日：2003-01-23
申请号：US10108511
申请日：2002-03-29
Inventor： Yoram Reiter , Avital Lev
IPC: A61K039/395
CPC classification number: C07K14/70539 , A61K2039/505 , C07K16/2866 , C07K16/30 , C07K2317/624 , C07K2319/00
Abstract: An immuno-molecule which comprises a soluble human MHC class I effector domain; and an antibody targeting domain which is linked to the soluble human MHC class I effector domain, methods of making same and uses thereof.
Abstract translation: 包含可溶性人MHC I类效应结构域的免疫分子; 和与可溶性人MHC I类效应结构域连接的抗体靶向结构域，其制备方法和用途。
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公开(公告)号：US20030003535A1
公开(公告)日：2003-01-02
申请号：US10073300
申请日：2002-02-13
Inventor： Yoram Reiter
IPC: C07K014/74 , C07H021/04 , C12P021/02 , C12N005/06
CPC classification number: C07K14/70539
Abstract: A recombinant polypeptide and nucleic acid constructs capable of expressing the recombinant polypeptide are provided. The recombinant polypeptide comprises a chimeric polypeptide including an antigenic peptide being capable of binding a human MHC class I, a functional human null-2 microglobulin and a functional human MHC class I heavy chain.
Abstract translation: 提供能够表达重组多肽的重组多肽和核酸构建体。 重组多肽包含嵌合多肽，其包括能够结合人MHC I类，功能性人β-2微球蛋白和功能性人MHC I类重链的抗原肽。
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