公开(公告)号：US06173420B2

公开(公告)日：2001-01-09

申请号：US08961793

申请日：1997-10-31

Applicant: Ramu V. Sunkara ,  Luk S. Ho ,  Paul F. Mackin ,  David Rowlands

Inventor： Ramu V. Sunkara ,  Luk S. Ho ,  Paul F. Mackin ,  David Rowlands

IPC: G06F1100

CPC classification number: G06F11/1415 ,  G06F9/44505

Abstract: A method and apparatus for configuring a software application on a cluster is provided. A configuration coordinator executing on a configuration manager communicates with one or more configuration slaves executing on a set of nodes that are operating as a cluster. The configuration coordinator sends messages to the one or more configuration slaves to initiate a configuration operation for a software application. Each configuration slave automatically performs a series of actions to configure the node on which it resides. When all the nodes complete the configuration operation for the software, the process is complete. While performing the series of actions, the configuration slaves generate logs that reflect their progress in performing the series of actions. If a problem occurs during performance of the series of actions, the configuration slave that encounters the problem indicates to the configuration coordinator that an error occurred. The configuration coordinator responds to the error by causing the configuration slaves to roll back changes made during performance of the series of actions. The configuration slaves that have begun but not completed the series of actions inspect their logs to determine which changes to roll back. By automatically configuring software on a cluster, and automatically rolling back changes on all cluster nodes in the event of an error during the configuration process, the cluster configuration process is made atomic, automatic, and significantly faster and less error-prone than manual cluster-wide configuration operations.

Abstract translation: 提供了一种用于在集群上配置软件应用的方法和装置。 在配置管理器上执行的配置协调器与在作为集群操作的一组节点上执行的一个或多个配置从站进行通信。 配置协调器向一个或多个配置从站发送消息，以启动软件应用程序的配置操作。 每个配置从站自动执行一系列操作来配置其所在的节点。 当所有节点完成软件的配置操作时，该过程完成。 在执行一系列操作时，配置从站会生成反映其执行一系列操作的进度的日志。 如果在执行一系列操作期间发生问题，则遇到此问题的配置从站将向配置协调器指示发生错误。 配置协调器通过使配置从站回滚执行一系列操作期间所做的更改来响应错误。 已经开始但尚未完成的配置从站系列操作检查其日志以确定要回滚的更改。 通过在集群中自动配置软件，并在配置过程中发生错误时自动回滚所有集群节点上的更改，集群配置过程的原子化，自动化和显着更快，并且比手动集群 - 宽配置操作。

公开(公告)号：US20070299108A1

公开(公告)日：2007-12-27

申请号：US11810981

申请日：2007-06-07

Applicant: Joseph Aszodi ,  Maxime Lampilas ,  Branislav Musicki ,  David Rowlands ,  Pascal Colette

Inventor： Joseph Aszodi ,  Maxime Lampilas ,  Branislav Musicki ,  David Rowlands ,  Pascal Colette

IPC: A61K31/47 ,  A61P43/00 ,  C07D215/00

CPC classification number: C07D215/38 ,  C07D217/22 ,  C07D217/26 ,  C07D471/04 ,  C07D471/08 ,  C07D491/04 ,  C07D495/04 ,  C07D513/04 ,  Y02P20/55

Abstract: The invention relates to new heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a process for the preparation of these compounds as well as their use as medicaments, in particular as anti-bacterial agents.

Abstract translation: 本发明涉及通式（I）的新型杂环化合物及其与碱或酸的盐：本发明还涉及这些化合物的制备方法及其用作药物，特别是抗 - 细菌剂。

公开(公告)号：US20050020572A1

公开(公告)日：2005-01-27

申请号：US10898754

申请日：2004-07-26

Applicant: Jozsef Aszodi ,  Claude Fromentin ,  Maxime Lampilas ,  David Rowlands

Inventor： Jozsef Aszodi ,  Claude Fromentin ,  Maxime Lampilas ,  David Rowlands

IPC: C07D487/08 ,  A61K31/397 ,  A61K31/4188 ,  A61K31/439 ,  A61K31/519 ,  A61K31/55 ,  A61P31/04 ,  A61P43/00 ,  C07D471/08 ,  C07D498/08

CPC classification number: A61K31/439 ,  A61K31/55 ,  A61K2300/00

Abstract: This invention discloses and claims methods for inhibiting bacterial β-lactamases and treating bacterial infections by inhibiting bacterial β-lactamases in man or an animal comprising administering a therapeutically effective amount to said man or said animal of a compound, or pharmaceutically acceptable salt thereof, of formula (I) either alone or in combination with a β-lactamine antibiotic wherein said combination can be administered separately, together or spaced out over time. Pharmaceutical compositions comprising a compound of formula (I), or a combination of a compound of formula (I) and a therapeutically effective amount of a β-lactamine antibiotic, and a pharmaceutically acceptable carrier are also disclosed and claimed.

Abstract translation: 本发明公开并要求通过抑制人或动物中的细菌β-内酰胺酶抑制细菌β-内酰胺酶和治疗细菌感染的方法，包括向所述人或所述动物施用治疗有效量的化合物或其药学上可接受的盐 式（I）单独或与β-内酰胺抗生素组合，其中所述组合可以分开施用，一起或随时间隔开。 还公开和要求保护包含式（I）化合物或式（I）化合物与治疗有效量的β-内酰胺抗生素和药学上可接受的载体的组合物的药物组合物。