公开(公告)号：US20060084802A1

公开(公告)日：2006-04-20

申请号：US11203006

申请日：2005-08-11

Applicant: Philippe Bergeron ,  Christopher Farthing ,  Stuart Jones ,  John Liebeschuetz ,  Sarah Lively ,  Lawrence McGee ,  Sharon McKendry ,  David Sheppard ,  Stephen Young

Inventor： Philippe Bergeron ,  Christopher Farthing ,  Stuart Jones ,  John Liebeschuetz ,  Sarah Lively ,  Lawrence McGee ,  Sharon McKendry ,  David Sheppard ,  Stephen Young

IPC: C07D417/02 ,  C07D413/02 ,  C07D403/02

CPC classification number: C07D239/47 ,  C07D213/75 ,  C07D237/22 ,  C07D239/42 ,  C07D239/46 ,  C07D239/48 ,  C07D239/52 ,  C07D239/54 ,  C07D239/58

Abstract: Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ or PPARδ. In particular, the compounds of the invention modulate the function of PPARγ or PPARδ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.