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">11.发明授权Compound "Leualacin", its preparation and its use in the treatment of cardiovascular disorders 失效化合物“利昔康宁”，其制备及其在治疗心血管疾病中的应用
公开(公告)号：US5112807A
公开(公告)日：1992-05-12
申请号：US403117
申请日：1989-09-05
Applicant: Kiyoshi Hamano , Kouhei Furuya , Kazuhiko Tanzawa , Takeshi Kagasaki , Masaaki Miyamoto , Takeshi Kinoshita
Inventor： Kiyoshi Hamano , Kouhei Furuya , Kazuhiko Tanzawa , Takeshi Kagasaki , Masaaki Miyamoto , Takeshi Kinoshita
IPC: C07D273/00 , C07D273/08 , C07K11/02 , C12P17/00
CPC classification number: C07D273/00 , C07K11/02 , C12P17/00 , C12R1/645 , Y10S435/911 , Y10S514/821 , Y10S514/929 , Y10S530/80
Abstract: A new compound, which we have named "Leualacin" has the formula (I): ##STR1## and may be prepared by cultivation of a microorganism of the genus Hapsidospora, especially Hapsidospora irregularis. The compound may be used for the treatment and prophylaxis of cardiovascular diseases and disorders, especially hypertension.
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