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公开(公告)号:US20090068720A1
公开(公告)日:2009-03-12
申请号:US12019793
申请日:2008-01-25
申请人: Katsutoshi Sasaki , Norihiko Shiraishi , Ayumi Natsume , Yoji Yamada , Satoshi Nakagawa , Susumu Sekine
发明人: Katsutoshi Sasaki , Norihiko Shiraishi , Ayumi Natsume , Yoji Yamada , Satoshi Nakagawa , Susumu Sekine
IPC分类号: C12N9/10
CPC分类号: C12N9/1051 , A61K38/00 , C07K2319/02 , C12N9/1085
摘要: The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyl transferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
摘要翻译: 本发明提供了具有β1,3-N-乙酰氨基葡糖酰转移酶活性的新型多肽; 一种生产该多肽的方法; 编码多肽的DNA; 插入DNA的重组载体; 包含重组载体的转化体; 使用该多肽制备糖链或复合碳水化合物的方法; 使用该转化体制备糖链或复合碳水化合物的方法; 识别多肽的抗体; 用于筛选改变编码多肽的基因表达的物质的方法; 以及筛选改变多肽活性的物质的方法。
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公开(公告)号:US20060030001A1
公开(公告)日:2006-02-09
申请号:US11148280
申请日:2005-06-09
申请人: Katsutoshi Sasaki , Norihiko Shiraishi , Ayumi Natsume , Yoji Yamada , Satoshi Nakagawa , Susume Sekine
发明人: Katsutoshi Sasaki , Norihiko Shiraishi , Ayumi Natsume , Yoji Yamada , Satoshi Nakagawa , Susume Sekine
CPC分类号: C12N9/1051 , A61K38/00 , C07K2319/02 , C12N9/1085
摘要: The present invention provides a novel polypeptide having a β1,3-N-acetylglucosaminyltransferase activity; a method for producing the polypeptide; a DNA which encodes the polypeptide; a recombinant vector into which the DNA is inserted; a transformant comprising the recombinant vector; a method for producing a sugar chain or complex carbohydrate, using the polypeptide; a method for producing a sugar chain or complex carbohydrate, using the transformant; an antibody which recognizes the polypeptide; a method for screening a substance which changes the expression of the gene which encodes the polypeptide; and a method for screening a substance which changes the activity of the polypeptide.
摘要翻译: 本发明提供了具有β1,3-N-乙酰葡糖胺基转移酶活性的新型多肽; 一种生产该多肽的方法; 编码多肽的DNA; 插入DNA的重组载体; 包含重组载体的转化体; 使用该多肽制备糖链或复合碳水化合物的方法; 使用该转化体生产糖链或复合碳水化合物的方法; 识别多肽的抗体; 用于筛选改变编码多肽的基因表达的物质的方法; 以及筛选改变多肽活性的物质的方法。
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