公开(公告)号：US20210323962A1

公开(公告)日：2021-10-21

申请号：US17309216

申请日：2019-11-11

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： George W. Griesgraber ,  Bryon A. Merrill ,  Michael J. Rice

IPC: C07D471/04 ,  A61K31/4745 ,  A61P37/04

Abstract: Imidazo[4,5-c]quinoline compounds having a substituent that is attached at the N−1 position by a branched group, single enantiomers of the compounds, pharmaceutical compositions containing the compounds, and methods of making the compounds are disclosed. Methods of use of the compounds as immune response modifiers, for inducing cytokine biosynthesis in humans and animals, and in the treatment of diseases including infectious and neoplastic diseases are also disclosed.

公开(公告)号：US09957428B2

公开(公告)日：2018-05-01

申请号：US15105103

申请日：2014-12-17

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Michael J. Bulinski ,  Michael G Costello ,  John G. Owens ,  Michael J. Rice

IPC: C09K5/04 ,  C08J9/14 ,  C08J9/00 ,  F28D15/00 ,  A61D1/00 ,  F01K25/08 ,  A62D1/00

CPC classification number: C09K5/045 ,  A62D1/0057 ,  A62D1/0092 ,  C08J9/0028 ,  C08J9/141 ,  C08J2375/04 ,  C09K2205/22 ,  F01K25/08 ,  F28D15/00

Abstract: A working fluid that includes a fluorinated olefin compound represented by the following general formula (I). In some embodiments, an apparatus for heat transfer is provided. The apparatus includes a device and a mechanism for transferring heat to or from the device. In some embodiments, a fire extinguishing composition is provided. In some embodiments, an apparatus for converting thermal energy into mechanical energy in a Rankine cycle is provided.