公开(公告)号：US20110291781A1

公开(公告)日：2011-12-01

申请号：US13063870

申请日：2010-08-27

申请人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

发明人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

IPC分类号： H01F1/00

CPC分类号： H01F7/0278 ,  G01R33/383

摘要： The magnetized structure that induces in a central area of interest a homogeneous magnetic field oriented along a longitudinal axis (z) of the structure comprises first and second magnetized rings (111, 121) disposed symmetrically relative to a plane (P) that is perpendicular to said longitudinal axis (z) and that contains said central area of interest, and one median annular magnetized structure (330) disposed between the first and second magnetized rings (111, 121) and also disposed symmetrically relative to the plane (P) of symmetry. The first magnetized ring (111) is magnetized radially relative to the longitudinal axis (z) with divergent magnetization, the second magnetized ring (121) is magnetized radially relative to the longitudinal axis (z) with convergent magnetization, and the median annular magnetized structure (330) is magnetized along the longitudinal axis (z). The median annular magnetized structure (330) is divided into at least two slices (331A, 331B, 332A, 332B) along the longitudinal axis (z) and the first and second magnetized rings (111, 121) and the various slices (331A, 331B, 332A, 332B) of the median magnetized structure (130) are each divided into identical components in the form of regularly distributed sectors.

摘要翻译： 在沿着该结构的纵向轴线（z）定向的均匀磁场的感兴趣的中心区域中感应的磁化结构包括相对于垂直于（...）的平面（P）对称设置的第一和第二磁化环（111,121） 所述纵向轴线（z）并且包含所述中心区域，以及设置在所述第一和第二磁化环（111,121）之间并且相对于对称平面（P）对称设置的一个中间环形磁化结构（330） 。 第一磁化环（111）相对于具有发散磁化的纵向轴线（z）被径向磁化，第二磁化环（121）相对于纵向轴线（z）径向磁化，并且中心环形磁化结构 （330）沿纵轴（z）被磁化。 中间环形磁化结构（330）沿着纵向轴线（z）和第一和第二磁化环（111,121）和各种切片（331A，331B，332A，332B）分成至少两个切片（331A，331B，332A，332B） 中间磁化结构（130）的各个部分331B，332A，332B分别以规则分布的扇区的形式分成相同的部件。

公开(公告)号：US06184683B2

公开(公告)日：2001-02-06

申请号：US09349085

申请日：1999-07-08

申请人： Lyndon Emsley ,  Dimitrios Sakellariou ,  Anne Lesage ,  Stefan Steuernagel

发明人： Lyndon Emsley ,  Dimitrios Sakellariou ,  Anne Lesage ,  Stefan Steuernagel

IPC分类号： G01V300

CPC分类号： G01R33/4641

摘要： A new two-dimensional NMR carbon-proton chemical shift correlation experiment, the MAS-J-HMQC experiment, is proposed for rotating solids. The magnetization transfer used to obtain the correlations is based on scalar heteronuclear J couplings. The 2D map provides through-bond chemical shift correlations between directly bonded proton carbon pairs in a similar way to corresponding high-resolution liquid state experiments. The transfer through J coupling is shown to be efficient and more selective that those based on heteronuclear dipolar couplings. The experiment, which works at high MAS spinning rates, yields the unambiguous assignment of the proton resonances. The experiment is demonstrated on several organic compounds.

摘要翻译： 提出了一种新的二维NMR碳 - 质子化学位移相关实验，MAS-J-HMQC实验用于旋转固体。 用于获得相关性的磁化转移基于标量异核J耦合。 2D图以与相应的高分辨率液态实验相似的方式提供直接键合的质子碳对之间的通键化学位移相关性。 通过J耦合的传递被证明是有效和更有选择性的那些基于异核偶极耦合的那些。 该实验以高MAS纺丝速率工作，产生质子共振的明确分配。 实验证明了几种有机化合物。

公开(公告)号：US08860539B2

公开(公告)日：2014-10-14

申请号：US13063875

申请日：2010-08-27

申请人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

发明人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

IPC分类号： H01F3/00 ,  H01F7/00 ,  H01F7/02 ,  G01R33/30 ,  G01R33/383

CPC分类号： G01R33/383 ,  G01R33/307 ,  H01F7/0278

摘要： A magnetized structure that induces in a central area of interest a homogeneous magnetic field of predetermined orientation relative to a longitudinal axis (z) of the structure comprises at least two magnetized rings (110, 120) disposed symmetrically relative to a plane (P) that is perpendicular to the longitudinal axis (z) and that contains the central area of interest, and at least one median annular magnetized structure disposed at least partly between the two magnetized rings (110, 120) and also disposed symmetrically relative to the plane (P) of symmetry, one of the two magnetized rings (110) being magnetized radially relative to the longitudinal axis (z) with divergent magnetization and the other of the two magnetized rings (120) being magnetized radially relative to the longitudinal axis (z) with convergent magnetization, and the median annular magnetized structure being magnetized with an orientation different from that of the magnetization of the two magnetized rings (110, 120). The median annular magnetized structure comprises at least one magnetized ring (150) having a magnetization distribution of orientation that varies as in Halbach dipoles and the first two magnetized rings (110, 120) and the median annular magnetized structure are each divided into individual components in the form of regularly distributed identical sectors.

摘要翻译： 感兴趣的中心区域的磁化结构相对于该结构的纵向轴线（z）具有预定取向的均匀磁场包括相对于平面（P）对称设置的至少两个磁化环（110,120），所述至少两个磁化环 垂直于所述纵向轴线（z）并且包含所述感兴趣的中心区域，以及至少一个中间环形磁化结构，其至少部分地设置在所述两个磁化环（110,120）之间，并且还相对于所述平面（P ）对称，两个磁化环（110）之一相对于纵向轴线（z）径向磁化，具有发散磁化，并且两个磁化环（120）中的另一个相对于纵向轴线（z）径向磁化， 收敛磁化，并且中间环形磁化结构被磁化，其方向不同于两个磁化环（110,120）的磁化强度 ）。 中间环形磁化结构包括至少一个磁化环（150），其具有如Halbach偶极子中变化的取向的磁化分布，并且前两个磁化环（110,120）和中间环形磁化结构各自被分成 定期分发相同部门的形式。

公开(公告)号：US08773230B2

公开(公告)日：2014-07-08

申请号：US13063870

申请日：2010-08-27

申请人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

发明人： Dimitrios Sakellariou ,  Cédric Hugon ,  Guy Aubert

IPC分类号： H01F3/00 ,  H01F7/00 ,  H01F7/02

CPC分类号： H01F7/0278 ,  G01R33/383

摘要： The magnetized structure that induces in a central area of interest a homogeneous magnetic field oriented along a longitudinal axis (z) of the structure comprises first and second magnetized rings (111, 121) disposed symmetrically relative to a plane (P) that is perpendicular to said longitudinal axis (z) and that contains said central area of interest, and one median annular magnetized structure (330) disposed between the first and second magnetized rings (111, 121) and also disposed symmetrically relative to the plane (P) of symmetry. The first magnetized ring (111) is magnetized radially relative to the longitudinal axis (z) with divergent magnetization, the second magnetized ring (121) is magnetized radially relative to the longitudinal axis (z) with convergent magnetization, and the median annular magnetized structure (330) is magnetized along the longitudinal axis (z). The median annular magnetized structure (330) is divided into at least two slices (331A, 331B, 332A, 332B) along the longitudinal axis (z) and the first and second magnetized rings (111, 121) and the various slices (331A, 331B, 332A, 332B) of the median magnetized structure (130) are each divided into identical components in the form of regularly distributed sectors.

摘要翻译： 在沿着该结构的纵向轴线（z）定向的均匀磁场的感兴趣的中心区域中感应的磁化结构包括相对于垂直于（...）的平面（P）对称设置的第一和第二磁化环（111,121） 所述纵向轴线（z）并且包含所述中心区域，以及设置在所述第一和第二磁化环（111,121）之间并且相对于对称平面（P）对称设置的一个中间环形磁化结构（330） 。 第一磁化环（111）相对于具有发散磁化的纵向轴线（z）被径向磁化，第二磁化环（121）相对于纵向轴线（z）径向磁化，并且中心环形磁化结构 （330）沿纵轴（z）被磁化。 中间环形磁化结构（330）沿着纵向轴线（z）和第一和第二磁化环（111,121）和各种切片（331A，331B，332A，332B）分成至少两个切片（331A，331B，332A，332B） 中间磁化结构（130）的各个部分331B，332A，332B分别以规则分布的扇区的形式分成相同的部件。

公开(公告)号：US20100156414A1

公开(公告)日：2010-06-24

申请号：US11993793

申请日：2006-07-05

申请人： Dimitrios Sakellariou ,  Jacques-Francois Jacquinot

发明人： Dimitrios Sakellariou ,  Jacques-Francois Jacquinot

IPC分类号： G01R33/48 ,  G01R33/44

CPC分类号： G01R33/34053 ,  G01R33/307 ,  G01R33/34092

摘要： The present invention concerns an apparatus (1′) for NMR spectroscopy and/or NMR imaging of a sample. The apparatus comprises a static probe comprising an outer coil for excitation of nuclei of said sample by generating an incident radio frequency field at the Larmor frequency of said nuclei, and for reception of a return radio frequency field emitted by said sample, and a sensitive inner coil (6a′) which is mounted closely around or in contact with the sample container and which is wirelessly coupled to said outer coil by an electromagnetic radio frequency field. The sensitive inner coil is embedded in an inner spinning rotor (2) which is rotatively mounted inside said static probe and which is integral with said sample container, so that the filling factor and the radio frequency field amplitude in said sensitive coil are maximized.

摘要翻译： 本发明涉及用于样品的NMR光谱和/或NMR成像的装置（1'）。 该装置包括静电探针，其包括用于通过产生所述核的拉莫尔频率处的入射射频场和用于接收所述样本发射的返回射频场的用于激发所述样本的核的外部线圈，以及敏感内部 线圈（6a'），其紧密地安装在样品容器周围或与样品容器接触，并且通过电磁射频场与所述外部线圈无线耦合。 敏感内圈嵌入内旋转转子（2）内，旋转安装在所述静电探头的内部，与所述样品容器成一体，使得所述感应线圈中的填充因数和射频场振幅最大化。