公开(公告)号：US20160374387A1

公开(公告)日：2016-12-29

申请号：US15192480

申请日：2016-06-24

Applicant: Altria Client Services LLC

Inventor： Andrew Carl ADAMS ,  Marcos Fernando de GODOY LUSSO ,  Sreepriya PRAMOD ,  Dongmei XU

IPC: A24B15/10 ,  A24D1/04 ,  A24D3/04 ,  A24B13/02 ,  A01H5/12 ,  A24B3/12

CPC classification number: A24B15/10 ,  A01H5/12 ,  A24B3/12 ,  A24B13/00 ,  A24B13/02 ,  A24D1/045 ,  A24D3/043 ,  C12N15/8243

Abstract: The present disclosure provides the identification of tobacco Nic1 locus. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Also provided are compositions and methods for producing tobacco plants having novel Nic1 mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or nicotine free while maintaining tobacco leaf grade and tobacco product quality.

Abstract translation: 本公开提供烟草Nic1基因座的鉴定。 还提供了具有改变的总生物碱和尼古丁水平和商业上可接受的叶子品级，通过育种或转基因方法发展的烟草植物以及来自这些烟草植物的烟草制品的生产。 还提供了用于生产具有新型Nic1突变或等位基因以减少尼古丁水平的烟草植物的组合物和方法。 进一步提供的是序列多态性和分子标记，用于在保持烟叶等级和烟草产品质量的同时养殖烟草，减少尼古丁或尼古丁。