公开(公告)号：US20240365741A1

公开(公告)日：2024-11-07

申请号：US18780938

申请日：2024-07-23

Applicant: Altria Client Services LLC

Inventor： Sreepriya PRAMOD ,  Marcos Fernando de GODOY LUSSO ,  Jesse FREDERICK ,  Andrew Carl ADAMS ,  Dongmei XU

IPC: A01H6/82 ,  A01H1/06 ,  A24B3/08 ,  A24B3/12 ,  A24B13/00 ,  A24B15/10 ,  A24B15/20 ,  A24B15/24 ,  C12N15/82

Abstract: The present disclosure provides tobacco Nic1b locus and associated genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US20240117370A1

公开(公告)日：2024-04-11

申请号：US18517109

申请日：2023-11-22

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Marcos Fernando de GODOY LUSSO ,  James A. STRICKLAND ,  Jesse FREDERICK ,  Dongmei XU ,  Chengalrayan KUDITHIPUDI

IPC: C12N15/82 ,  A24B13/00

CPC classification number: C12N15/8225 ,  A24B13/00 ,  C12N15/8218 ,  C12N15/8243 ,  C12N15/8261

Abstract: The present disclosure includes methods and compositions for improving leaf quality in low-alkaloid tobacco plants, e.g., by combining inducible promoters and non-coding RNAs for suppression of an ornithine decarboxylase (ODC) gene. Also provided are low alkaloid tobacco plants with normal, suppressed, or otherwise altered polyamine levels. Further provided are tobacco plants with altered total alkaloid, nicotine levels, commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants.

公开(公告)号：US20240018534A1

公开(公告)日：2024-01-18

申请号：US18450522

申请日：2023-08-16

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Jaemo YANG ,  Yanxin SHEN ,  Dongmei XU ,  Ujwala WAREK ,  James Strickland ,  Jesse FREDERICK

IPC: C12N15/82

CPC classification number: C12N15/8205 ,  C12N15/8229

Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20230363344A1

公开(公告)日：2023-11-16

申请号：US18321594

申请日：2023-05-22

Applicant: Altria Client Services LLC

Inventor： Andrew C. ADAMS ,  Marcos F. de GODOY LUSSO ,  Sreepriya PRAMOD ,  Dongmei XU

IPC: A01H6/82 ,  A01H5/12

CPC classification number: A01H6/823 ,  A01H5/12

Abstract: The present application provides tobacco inbred plants dS1746, dS1746MS, dS1564 and dS1564MS. The present application also provides parts of such plants and products made from those parts. The present application also includes progeny of the provided plants including hybrids.

公开(公告)号：US20230247961A1

公开(公告)日：2023-08-10

申请号：US17892461

申请日：2022-08-22

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Jesse FREDERICK ,  Yanxin SHEN ,  Dongmei XU ,  Ujwala WAREK ,  James Arthur STRICKLAND

IPC: A01H6/82 ,  C07K14/415 ,  C12N15/82 ,  A01H5/12 ,  A01H1/02 ,  A01H1/06 ,  A24B15/20 ,  C12Q1/6895 ,  G01N33/00

CPC classification number: A01H6/823 ,  C07K14/415 ,  C12N15/8243 ,  A01H5/12 ,  A01H1/02 ,  A01H1/06 ,  A24B15/20 ,  C12Q1/6895 ,  G01N33/0098 ,  C12Q2600/13 ,  C12Q2600/156 ,  C12Q2600/16

Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.

公开(公告)号：US20220395014A1

公开(公告)日：2022-12-15

申请号：US17892239

申请日：2022-08-22

Applicant: Altria Client Services LLC

Inventor： Yahya KARGA ,  James POWELL ,  Dongmei XU ,  James A. STRICKLAND ,  Ujwala WAREK

IPC: A24B15/22 ,  A24B15/18 ,  A24B13/00

Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.

公开(公告)号：US20220010324A1

公开(公告)日：2022-01-13

申请号：US17337161

申请日：2021-06-02

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Sreepriya PRAMOD ,  Marcos Fernando de GODOY LUSSO ,  Jesse FREDERICK ,  Andrew ADAMS ,  Dongmei XU

IPC: C12N15/82

Abstract: The present disclosure provides tobacco having genetic modification(s) in a group of ERF genes. Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.

公开(公告)号：US20210230627A1

公开(公告)日：2021-07-29

申请号：US17150704

申请日：2021-01-15

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Jesse FREDERICK ,  Andrew Carl ADAMS ,  Dongmei XU

IPC: C12N15/82

Abstract: The present disclosure provides products, compositions, and methods for improving nitrogen use efficiency in tobacco plants, including e.g., Burley tobacco. This disclosure further provides genetic markers for tracking enhanced nitrogen use efficiency phenotypes in tobacco plants and for introgressing enhanced nitrogen use efficiency phenotypes into tobacco plants. The disclosure also provides tobacco plants comprising enhanced nitrogen use efficiency and methods to the creation of tobacco plants comprising enhanced nitrogen use efficiency.

公开(公告)号：US20200037656A1

公开(公告)日：2020-02-06

申请号：US16441972

申请日：2019-06-14

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Elisabeth MILLER ,  Ujwala WAREK ,  Dongmei XU

IPC: A24B15/30 ,  A24B15/20 ,  C07K14/005 ,  C12N7/00 ,  C12N9/80 ,  A24B15/24 ,  A01N63/00 ,  A24B15/18

Abstract: Bacteriophage against Geobacillus are provided, and methods of making and using the bacteriophage also are provided.

公开(公告)号：US20240376488A1

公开(公告)日：2024-11-14

申请号：US18782700

申请日：2024-07-24

Applicant: Altria Client Services LLC

Inventor： Chengalrayan KUDITHIPUDI ,  Dongmei XU ,  James A. STRICKLAND ,  Marcos Fernando de Godoy Lusso

IPC: C12N15/82

Abstract: The present disclosure provides approaches for reducing nicotine. Also provided are tobacco plants with decreased tobacco-specific nitrosamines (TSNAs). The present disclosure further provides modified tobacco plants with low nicotine and increased antioxidant capacity. Further provided are tobacco plants or material with low nicotine and low TSNAs. Also provided is cured tobacco material of the tobacco plants provided herein and tobacco products comprising this cured tobacco material.