公开(公告)号：US20230060660A1

公开(公告)日：2023-03-02

申请号：US17957551

申请日：2022-09-30

Applicant: Avanpore LLC

Inventor： Benjamin Bikson

IPC: B01J20/28 ,  B01D69/02 ,  B01J20/32 ,  B01D63/02 ,  B01D67/00 ,  B01J20/30 ,  B01J20/26 ,  C07C7/11 ,  B01D61/24 ,  C07C7/12 ,  B01D69/08 ,  B01D71/52

Abstract: A process for the efficient transfer of molecules between phases employing mesoporous poly (aryl ether ketone) hollow fiber membranes is provided. The method addresses the controlled transfer of reactants into and removal of reaction products from a reaction media and the removal and separation of target molecules from process streams by membrane-assisted liquid-liquid extraction. A number of possible modes of liquid-liquid extraction are possible according to the invention by utilizing porous poly (aryl ether ketone) hollow fiber membranes of Janus-like structure that exhibit a combination of hydrophilic and hydrophobic surface characteristics. The method of the present invention can address the continuous manufacture of chemicals in membrane reactors and is useful for a broad range of separation applications, including separation and recovery of active pharmaceutical ingredients.

公开(公告)号：US11511238B1

公开(公告)日：2022-11-29

申请号：US17862810

申请日：2022-07-12

Applicant: Avanpore LLC

Inventor： Benjamin Bikson

IPC: B01D71/52 ,  B01D67/00 ,  B01D69/12

Abstract: Disclosed is the preparation of composite fluid separation membranes based on poly (aryl ether ketone) (PAEK) polymers with the separation layer formed by a layer-by-layer reticular synthesis. The porous PAEK substrate is semicrystalline, exhibits a mesoporous surface structure, and is surface functionalized. The separation layer formed by the hierarchical layer-by-layer process is in the form of a covalent organic network integrally linked via covalent bonds to the functional groups of the substrate. The composite separation layer may be synthesized in situ in a preformed separation device on the surface of the PAEK substrate. Device configurations include flat sheet, spiral wound, monolith, and hollow fiber configurations with the hollow fiber configuration being preferred. Hollow fibers are formed from PAEK polymers with poly (ether ether ketone) and poly (ether ketone) particularly preferred. Composite PAEK membranes of the present invention are useful for a broad range of fluid separation applications.