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公开(公告)号：US10189829B2
公开(公告)日：2019-01-29
申请号：US16113455
申请日：2018-08-27
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US12240838B2
公开(公告)日：2025-03-04
申请号：US17610963
申请日：2020-05-15
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Jürgen Schulz , Marta Nevalainen
IPC: C07D413/12 , C07D401/12 , C07D413/14 , C07D417/12
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US20250034150A1
公开(公告)日：2025-01-30
申请号：US18709273
申请日：2022-11-10
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Jürgen Schulz , Marta Nevalainen , TeYu Chen , Robin Prince , Harold George Vandeveer , Isaac Marx , Simone Sciabola , Zain Yousaf
IPC: C07D487/04 , A61K31/437 , A61K31/4985 , A61K31/519 , A61K31/5377 , A61K31/55 , C07D471/04 , C07D519/00
Abstract: Provided are compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein the variables in Formula (I) are as defined herein; and methods for their use and production.
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公开(公告)号：US20240327380A1
公开(公告)日：2024-10-03
申请号：US18019540
申请日：2021-08-05
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Isaac Marx , Jürgen Schulz , Harold George Vandeveer , Robin Prince , Marta Nevalainen , TeYu Chen , Zain Yousaf , Martin Himmelbauer , Vatee Pattaropong , John Howard Jones , Rab Gilfillan , Edward Yin Shiang Lin , Felix Gonzalez Lopez de Turiso , Bin Ma
IPC: C07D401/14 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/553 , C07D401/12 , C07D403/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D471/08 , C07D487/10
CPC classification number: C07D401/14 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/506 , A61K31/5377 , A61K31/55 , A61K31/553 , C07D401/12 , C07D403/12 , C07D413/12 , C07D413/14 , C07D471/04 , C07D471/08 , C07D487/10
Abstract: Provided are compounds of Formula (I): or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R7, R8, R9, A1, A2, Q1, Q2, Q3, A, Z, m and n are as defined herein; pharmaceutical compositions comprising said compounds or pharmaceutically acceptable salts thereof, and pharmaceutically acceptable excipients; and methods of treating a disorder responsive to inhibition of Bruton's tyrosine kinase using said compounds, or pharmaceutically acceptable salts thereof, or said pharmaceutical compositions.
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公开(公告)号：US20230121818A1
公开(公告)日：2023-04-20
申请号：US17788127
申请日：2020-12-23
Applicant: BIOGEN MA INC.
Inventor： Bin Ma , Brian T. Hopkins , Isaac Marx , Jürgen Schulz , George Vandeveer , Robin Prince , Marta Nevalainen , TeYu Chen , Zain Yousaf , Andrew George Capacci
IPC: C07D401/14 , C07D413/12 , C07D471/04 , C07D403/12 , C07D403/10 , C07D495/04 , C07D401/12 , C07D413/14
Abstract: Provided are compounds of Formula (I′) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R8, R9, R11A, R11B, R12, Ri, Rii, A1, A2, Q1, Q2, Q3, X, W, and n are as defined herein; pharmaceutical compositions comprising said compounds or pharmaceutically acceptable salts thereof, and pharmaceutically acceptable excipients; and methods of treating a disorder responsive to inhibition of Bruton's tyrosine kinase using said compounds, or pharmaceutically acceptable salts thereof, or said pharmaceutical compositions.
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Patent Agency Ranking
公开(公告)号：US20230025892A1
公开(公告)日：2023-01-26
申请号：US17773418
申请日：2020-10-29
Applicant: BIOGEN MA INC.
Inventor： Isaac Marx , Jürgen Schulz , Brian T. Hopkins , Bin Ma , Robin Prince , Marta Nevalainen
IPC: C07D487/04 , C07D519/00
Abstract: Provided are compounds of Formula (I): Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4, R5, R6, A1, B1, B2, Q1 and Q2 are as defined herein; and methods for their use and production.
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公开(公告)号：US11427577B2
公开(公告)日：2022-08-30
申请号：US17183702
申请日：2021-02-24
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US20220259194A1
公开(公告)日：2022-08-18
申请号：US17610963
申请日：2020-05-15
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Jürgen Schulz , Marta Nevalainen
IPC: C07D413/12 , C07D413/14 , C07D401/12 , C07D417/12
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US20200239459A1
公开(公告)日：2020-07-30
申请号：US16534540
申请日：2019-08-07
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , A61P43/00 , C07D405/14 , C07D471/04 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号：US10227341B2
公开(公告)日：2019-03-12
申请号：US15952505
申请日：2018-04-13
Applicant: BIOGEN MA INC.
Inventor： Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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