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公开(公告)号:US11820760B2
公开(公告)日:2023-11-21
申请号:US17283301
申请日:2019-10-15
Applicant: BIOGEN MA INC.
Inventor: Fengmei Zheng , Anton Peterson , Kalyan Vasudevan , Chaomin Li , Daniel B. Patience , Yiqing Lin
IPC: C07D405/14
CPC classification number: C07D405/14 , C07B2200/13
Abstract: Provided are crystalline forms of (R)-1-(tert-butyl)-N-(8-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-2-(oxetan-3-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-yl)-1H-1,2,3-triazole-4-carboxamide, pharmaceutical compositions, methods of use and methods of making thereof.
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公开(公告)号:US20180297992A1
公开(公告)日:2018-10-18
申请号:US15952505
申请日:2018-04-13
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
CPC classification number: C07D417/14 , A61K31/44 , A61K31/443 , A61K31/506 , A61P43/00 , C07B2200/13 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US20210340135A1
公开(公告)日:2021-11-04
申请号:US17183702
申请日:2021-02-24
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , A61P43/00 , C07D405/14 , C07D471/04 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US20180362522A1
公开(公告)日:2018-12-20
申请号:US16113455
申请日:2018-08-27
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , A61P43/00 , C07D403/14 , C07D405/14 , C07D413/14
CPC classification number: C07D417/14 , A61K31/44 , A61K31/443 , A61K31/506 , A61P43/00 , C07B2200/13 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US10189829B2
公开(公告)日:2019-01-29
申请号:US16113455
申请日:2018-08-27
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D405/14 , C07D413/14 , A61P43/00
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US11427577B2
公开(公告)日:2022-08-30
申请号:US17183702
申请日:2021-02-24
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US20200239459A1
公开(公告)日:2020-07-30
申请号:US16534540
申请日:2019-08-07
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , A61P43/00 , C07D405/14 , C07D471/04 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US11858926B2
公开(公告)日:2024-01-02
申请号:US17871157
申请日:2022-07-22
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
CPC classification number: C07D417/14 , A61P1/16 , A61P43/00 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07B2200/13
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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公开(公告)号:US10961237B2
公开(公告)日:2021-03-30
申请号:US16534540
申请日:2019-08-07
Applicant: BIOGEN MA INC.
Inventor: Brian T. Hopkins , Bin Ma , Robin Prince , Isaac Marx , Joseph P. Lyssikatos , Fengmei Zheng , Matthew Peterson , Daniel B. Patience
IPC: C07D417/14 , C07D403/14 , C07D413/14 , C07D405/14 , C07D471/04 , A61P43/00 , A61P1/16
Abstract: Provided are compounds of Formula (I), or pharmaceutically acceptable salts thereof, and methods for their use and production.
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