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11.发明授权Pyridin-3-yl acetic acid derivatives as inhibitors of human immunodeficiency virus replication 有权吡啶-3-基乙酸衍生物作为人免疫缺陷病毒复制的抑制剂公开(公告)号：US09193720B2
公开(公告)日：2015-11-24
申请号：US14619438
申请日：2015-02-11
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： B. Narasimhulu Naidu , Manoj Patel , Jeffrey Lee Romine , Denis R. St. Laurent , Tao Wang , Zhongxing Zhang , John F. Kadow
IPC: C07D213/24 , A61K31/00 , C07D417/14 , C07D401/04 , C07D401/14 , C07D409/14 , C07D413/14
CPC classification number: C07D417/14 , C07D213/61 , C07D401/04 , C07D401/14 , C07D409/14 , C07D413/14
Abstract: The disclosure generally relates to compounds of formula I, II, III and IV, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
Abstract translation: 本公开一般涉及式I，II，III和IV的化合物，包括用于治疗人类免疫缺陷病毒（HIV）感染的组合物和方法。 本公开提供了HIV的新型抑制剂，含有这些化合物的药物组合物，以及使用这些化合物治疗HIV感染的方法。
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公开(公告)号：US08846023B2
公开(公告)日：2014-09-30
申请号：US14021686
申请日：2013-09-09
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: C07D403/14 , C07D405/14 , C07D417/14 , A61K31/506 , A61K31/4178 , A61K31/427 , A61K31/13 , A61K31/7105 , A61K31/4745 , A61K31/7056 , A61K38/20 , A61K38/21 , C07D401/14
CPC classification number: A61K31/506 , A61K31/13 , A61K31/4178 , A61K31/427 , A61K31/4745 , A61K31/7056 , A61K31/7105 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US11046675B2
公开(公告)日：2021-06-29
申请号：US16499009
申请日：2018-03-26
Applicant: Bristol-Myers Squibb Company
Inventor： Kap-Sun Yeung , Denis R. St. Laurent , Jeffrey Lee Romine , Paul Michael Scola
IPC: C07D405/14 , C07D401/12 , C07D401/14 , C07D405/12 , A61K45/06
Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various pp diseases, including cancer and infectious diseases. (I)
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公开(公告)号：US09561212B2
公开(公告)日：2017-02-07
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178 , C07D403/14
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20160338999A1
公开(公告)日：2016-11-24
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: A61K31/4178 , C07D403/14 , C07D405/14 , A61K45/06
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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Patent Agency Ranking
公开(公告)号：US20160311778A1
公开(公告)日：2016-10-27
申请号：US15194980
申请日：2016-06-28
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: C07D233/64 , C07D405/14 , C07D413/14 , C07D409/14 , C07D417/14 , C07D403/14 , C07D401/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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17.发明申请PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION 有权作为人免疫缺陷病毒复制的抑制剂的吡啶-3-乙酸衍生物公开(公告)号：US20150232463A1
公开(公告)日：2015-08-20
申请号：US14619438
申请日：2015-02-11
Applicant: Bristol-Myers Squibb Company
Inventor： B. Narasimhulu Naidu , Manoj Patel , Jeffrey Lee Romine , Denis R. St. Laurent , Tao Wang , Zhongxing Zhang , John F. Kadow
IPC: C07D417/14 , C07D413/14 , C07D409/14 , C07D401/04 , C07D401/14
CPC classification number: C07D417/14 , C07D213/61 , C07D401/04 , C07D401/14 , C07D409/14 , C07D413/14
Abstract: The disclosure generally relates to compounds of formula I, II, III and IV, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
Abstract translation: 本公开一般涉及式I，II，III和IV的化合物，包括用于治疗人类免疫缺陷病毒（HIV）感染的组合物和方法。 本公开提供了HIV的新型抑制剂，含有这些化合物的药物组合物，以及使用这些化合物治疗HIV感染的方法。
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公开(公告)号：US09018390B2
公开(公告)日：2015-04-28
申请号：US13919027
申请日：2013-06-17
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D233/00 , C07D233/02 , A01N43/50 , A61K31/415 , C07D403/14 , A61K31/4178 , A61K31/4545 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07F7/10
CPC classification number: C07D403/14 , A61K31/4178 , A61K31/4545 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07F7/10
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Abstract translation: 本公开涉及用于治疗丙型肝炎病毒（HCV）感染的化合物，组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号：US20150011754A1
公开(公告)日：2015-01-08
申请号：US14488990
申请日：2014-09-17
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D413/14 , C07D401/14 , C07D233/64 , C07D403/14 , C07D405/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20140017195A1
公开(公告)日：2014-01-16
申请号：US14021686
申请日：2013-09-09
Applicant: Bristol-Myers Squibb Company
Inventor： Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavole , Omar D. Lopez , Alain Martel , Nicolas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K31/506 , A61K31/4178 , C07D417/14 , A61K31/427 , A61K31/13 , A61K38/20 , A61K38/21 , A61K31/7105 , A61K31/4745 , A61K31/7056 , C07D403/14 , C07D405/14
CPC classification number: A61K31/506 , A61K31/13 , A61K31/4178 , A61K31/427 , A61K31/4745 , A61K31/7056 , A61K31/7105 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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