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公开(公告)号：US09561212B2
公开(公告)日：2017-02-07
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178 , C07D403/14
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20160338999A1
公开(公告)日：2016-11-24
申请号：US15227709
申请日：2016-08-03
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Jeffrey Lee Romine , Zhong Yang , Gan Wang , Van N. Nguyen , John A. Bender , Denis R. St. Laurent , Makonen Belema
IPC: A61K31/4178 , C07D403/14 , C07D405/14 , A61K45/06
CPC classification number: A61K31/4178 , A61K45/06 , C07D403/14 , C07D405/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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13.发明申请4,4'-BIPHENYLDIYL-BIS-(1 H-IMIDAZOLYL) DERIVATIVES AS HEPATITIS HCV INHIBITORS 审中-公开作为丙型肝炎病毒抑制剂的4,4'-联苯二甲酸二（B） - （1H-咪唑啉）衍生物公开(公告)号：US20160311806A1
公开(公告)日：2016-10-27
申请号：US15100681
申请日：2014-12-02
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： John A. Bender , Zhong Yang , Makonen Belema
IPC: C07D405/14 , A61K45/06 , A61K31/4178
CPC classification number: C07D405/14 , A61K31/4178 , A61K45/06
Abstract: The present disclosure relates to compounds of formula (I), pharmaceutical compositions and use thereof in treatment of hepatitis C virus (HCV) infection.
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公开(公告)号：US20150322048A1
公开(公告)日：2015-11-12
申请号：US14807084
申请日：2015-07-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D403/14 , A61K45/06 , A61K31/4178 , A61K31/4545 , C07D471/04 , A61K31/437 , C07D487/04 , A61K31/4985 , C07D405/14 , C07D401/14 , A61K31/4709 , A61K31/498 , A61K31/4375 , C07D413/14 , A61K31/5377 , A61K31/4184
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20140186299A1
公开(公告)日：2014-07-03
申请号：US14197343
申请日：2014-03-05
Applicant: Bristol-Myers Squibb Company
Inventor： John A. Bender , Min Ding , Robert G. Gentles , Piyasena Hewawasam
IPC: C07D487/08 , A61K31/55 , A61K45/06
CPC classification number: C07D487/08 , A61K31/55 , A61K45/06 , C07D471/08 , C07D487/04 , C07D519/00
Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
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Patent Agency Ranking
公开(公告)号：US20140045816A1
公开(公告)日：2014-02-13
申请号：US14048856
申请日：2013-10-08
Applicant: Bristol-Myers Squibb Company
Inventor： John A. Bender , Min Ding , Robert G. Gentles , Piyasena Hewawasam
IPC: C07D487/04 , C07D471/08
CPC classification number: C07D487/08 , A61K31/55 , A61K45/06 , C07D471/08 , C07D487/04 , C07D519/00
Abstract: The invention encompasses compounds of formula I as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and are useful in treating those infected with HCV.
Abstract translation: 本发明包括式I化合物以及使用该化合物的组合物和方法。 该化合物具有抗丙型肝炎病毒（HCV）的活性，可用于治疗HCV感染者。
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公开(公告)号：US09776981B2
公开(公告)日：2017-10-03
申请号：US14807084
申请日：2015-07-23
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D487/04 , C07D309/06 , C07D401/14 , C07D403/14 , C07D471/04 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D403/10 , C07D405/14 , C07D413/14
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US09340520B2
公开(公告)日：2016-05-17
申请号：US14017837
申请日：2013-09-04
Applicant: Bristol-Myers Squibb Company
Inventor： Omar D. Lopez , John A. Bender , Makonen Belema
IPC: C07D309/06 , C07D405/14 , A61K45/06 , A61K31/4178
CPC classification number: C07D309/06 , A61K31/4178 , A61K45/06 , C07D405/14 , A61K2300/00
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号：US20160052924A1
公开(公告)日：2016-02-25
申请号：US14779648
申请日：2014-03-25
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor： Tao Wang , Zhiwei Yin , Zhongxing Madison , John A. Bender , Barry L. Johnson , Jhon F. Kadow , Nicholas A. Meanwell
IPC: C07D471/04 , A61K31/4545 , A61K45/06 , C07D401/06 , A61K31/454 , A61K31/437 , A61K31/55
CPC classification number: C07D471/04 , A61K31/437 , A61K31/454 , A61K31/4545 , A61K31/55 , A61K45/06 , C07D401/06 , C07D519/00
Abstract: Compounds of Formula I, including pharmaceutically acceptable salts thereof: I useful as HIV attachment inhibitors.
Abstract translation: 式I的化合物，包括其药学上可接受的盐：可用作HIV附着抑制剂。
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公开(公告)号：US20150197499A1
公开(公告)日：2015-07-16
申请号：US14668090
申请日：2015-03-25
Applicant: Bristol-Myers Squibb Company
Inventor： Rico Lavoie , John A. Bender , Zhong Yang , Makonen Belema , Omar D. Lopez , Qi Chen , Gan Wang , Piyasena Hewawasam
IPC: C07D309/06
CPC classification number: C07D309/06 , A61K31/4178 , A61K31/4184 , A61K31/437 , A61K31/4375 , A61K31/4545 , A61K31/4709 , A61K31/498 , A61K31/4985 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D403/10 , C07D403/14 , C07D405/14 , C07D413/14 , C07D471/04 , C07D487/04
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of Hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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