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11.
公开(公告)号:US09193725B2
公开(公告)日:2015-11-24
申请号:US14384410
申请日:2013-03-13
Applicant: BRISTOL-MYERS SQUIBB COMPANY
Inventor: Tao Wang , John F. Kadow , Nicholas A. Meanwell , Lawrence G. Hamann
IPC: C07D487/00 , C07D401/00 , C07D471/04 , C07D519/00 , A61K31/501 , A61K31/519 , A61K45/06
CPC classification number: C07D471/04 , A61K31/501 , A61K31/519 , A61K45/06 , C07D519/00
Abstract: Compounds of Formula I are provided, including pharmaceutically acceptable salts thereof: wherein A is selected from the group consisting of: wherein Z is selected from the group consisting of: which are useful as HIV attachment inhibitors.
Abstract translation: 提供了式I化合物,包括其药学上可接受的盐:其中A选自:其中Z选自:其可用作HIV附着抑制剂。
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公开(公告)号:US09018390B2
公开(公告)日:2015-04-28
申请号:US13919027
申请日:2013-06-17
Applicant: Bristol-Myers Squibb Company
Inventor: Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D233/00 , C07D233/02 , A01N43/50 , A61K31/415 , C07D403/14 , A61K31/4178 , A61K31/4545 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07F7/10
CPC classification number: C07D403/14 , A61K31/4178 , A61K31/4545 , A61K31/5377 , A61K31/695 , A61K45/06 , C07D401/14 , C07F7/10
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
Abstract translation: 本公开涉及用于治疗丙型肝炎病毒(HCV)感染的化合物,组合物和方法。 还公开了含有这些化合物的药物组合物和使用这些化合物治疗HCV感染的方法。
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公开(公告)号:US20150011754A1
公开(公告)日:2015-01-08
申请号:US14488990
申请日:2014-09-17
Applicant: Bristol-Myers Squibb Company
Inventor: Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavoie , Omar D. Lopez , Alain Martel , Nicholas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Lawrence G. Hamann
IPC: C07D413/14 , C07D401/14 , C07D233/64 , C07D403/14 , C07D405/14
CPC classification number: C07D233/64 , A61K31/4178 , A61K45/06 , C07D207/16 , C07D401/14 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F5/025 , C07F7/0812
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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公开(公告)号:US20140017195A1
公开(公告)日:2014-01-16
申请号:US14021686
申请日:2013-09-09
Applicant: Bristol-Myers Squibb Company
Inventor: Carol Bachand , Makonen Belema , Daniel H. Deon , Andrew C. Good , Jason Goodrich , Clint A. James , Rico Lavole , Omar D. Lopez , Alain Martel , Nicolas A. Meanwell , Van N. Nguyen , Jeffrey Lee Romine , Edward H. Ruediger , Lawrence B. Snyder , Denis R. St. Laurent , Fukang Yang , David R. Langley , Gan Wang , Lawrence G. Hamann
IPC: A61K31/506 , A61K31/4178 , C07D417/14 , A61K31/427 , A61K31/13 , A61K38/20 , A61K38/21 , A61K31/7105 , A61K31/4745 , A61K31/7056 , C07D403/14 , C07D405/14
CPC classification number: A61K31/506 , A61K31/13 , A61K31/4178 , A61K31/427 , A61K31/4745 , A61K31/7056 , A61K31/7105 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/14 , C07D403/14 , C07D405/14 , C07D417/14
Abstract: The present disclosure relates to compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
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