公开(公告)号：US07689022B2

公开(公告)日：2010-03-30

申请号：US10389194

申请日：2003-03-14

Applicant: Nathan K. Weiner ,  Patrick J. Odoy ,  Erik Schultz ,  Mark Jones ,  James Overbeck ,  Herman Deweerd ,  David A. Stura ,  Albert Bukys ,  Tim Woolaver ,  Thomas P. Regan ,  David Bradbury ,  Eric Earl McKenzie ,  Roger DiPaolo ,  Christopher Miles ,  Joel Katz ,  Ksenia Oleink-Ovod

Inventor： Nathan K. Weiner ,  Patrick J. Odoy ,  Erik Schultz ,  Mark Jones ,  James Overbeck ,  Herman Deweerd ,  David A. Stura ,  Albert Bukys ,  Tim Woolaver ,  Thomas P. Regan ,  David Bradbury ,  Eric Earl McKenzie ,  Roger DiPaolo ,  Christopher Miles ,  Joel Katz ,  Ksenia Oleink-Ovod

IPC: G06K9/00

CPC classification number: G01N21/6428 ,  G01N21/253 ,  G01N21/6452 ,  G01N2021/6471

Abstract: An embodiment of a scanning system is described including optical elements that direct an excitation beam at a probe array, detectors that receive reflected intensity data responsive to the excitation beam, where the reflected intensity data is responsive to a focusing distance between an optical element and the probe array, a transport frame that adjusts the focusing distance in a direction with respect to the probe array, an auto-focuser that determines a best plane of focus based upon characteristics of the reflected intensity data of at least two focusing distances where the detectors further receive pixel intensity values based upon detected emissions from a plurality of probe features disposed on the probe array at the best plane of focus, and an image generator that associates each of the pixel intensity values with at least one image pixel position of a probe array based upon one or more position correction values.

公开(公告)号：US07406391B2

公开(公告)日：2008-07-29

申请号：US11231266

申请日：2005-09-20

Applicant: Christopher Miles

Inventor： Christopher Miles

IPC: G06F19/00 ,  G01B11/14

CPC classification number: G01N21/274 ,  G01N21/6428 ,  G01N21/6452

Abstract: In one embodiment, a method of determining a drift value is described that includes performing one or more X-axis translations of an excitation beam over a probe array; measuring light responsive to the excitation beam from at least two positional reference elements associated with the probe array for the X-axis translations; calculating a distance value for the X-axis translation using a positional relationship of a known location associated with each of the positional reference elements and positions of the positional reference elements from the measured light; and determining a drift value using a difference between the calculated distance value and an expected distance value.

Abstract translation: 在一个实施例中，描述了确定漂移值的方法，其包括在探针阵列上执行激发束的一个或多个X轴平移; 测量响应于来自与用于X轴平移的探针阵列相关联的至少两个位置参考元件的激发光束的光; 使用与所述位置参考元素中的每一个相关联的已知位置和所述位置参考元素与所测量的光的位置的位置关系来计算所述X轴平移的距离值; 以及使用所计算的距离值和预期距离值之间的差来确定漂移值。