公开(公告)号：US20190133903A1

公开(公告)日：2019-05-09

申请号：US16178788

申请日：2018-11-02

Applicant: Colgate-Palmolive Company

Inventor： Kavita VEMISHETTI ,  Linh FRUGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/24 ,  A61K8/21 ,  A61K8/365 ,  A61Q11/00 ,  A61K8/19

Abstract: An oral care composition containing a source of stannous ions, a source of fluoride ions and an insoluble source of zinc ions, such as zinc oxide. The composition contains an amount of citric acid sufficient to increase the level of soluble zinc ions.

公开(公告)号：US20170348206A1

公开(公告)日：2017-12-07

申请号：US15538285

申请日：2014-12-26

Applicant: Colgate-Palmolive Company

Inventor： Kavita VEMISHETTI ,  Linh FRUGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/21 ,  A61K8/24 ,  A61Q11/00

Abstract: The present disclosure provides low water dentifrice compositions comprising an effective amount of a zinc ion source, a tin ion source, a polyphosphate and an acid. The acid lowers the pH of the composition to enable stabilization of the metal ions and extend shelf-life of the composition.

公开(公告)号：US20170319447A1

公开(公告)日：2017-11-09

申请号：US15319636

申请日：2014-06-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Kavita VEMISHETTI ,  Linh FRUGE ,  Michael PRENCIPE

IPC: A61K8/27 ,  A61K8/365 ,  A61K8/24 ,  A61Q11/00 ,  A61K8/21

CPC classification number: A61K8/27 ,  A61K8/19 ,  A61K8/21 ,  A61K8/24 ,  A61K8/365 ,  A61Q11/00

Abstract: An oral care composition containing a source of stannous ions, a source of fluoride ions and an insoluble source of zinc ions, such as zinc oxide. The composition contains an amount of citric acid sufficient to increase the level of soluble zinc ions.