公开(公告)号：US20160199346A1

公开(公告)日：2016-07-14

申请号：US14965062

申请日：2015-12-10

Applicant: EpicentRx, Inc. ,  Orbital ATK, Inc.

Inventor： MARK D. BEDNARSKI ,  Susan Knox ,  Louis Cannizzo ,  Kirstin Warner ,  Robert Wardle ,  Stephen Velarde ,  Shoucheng Ning

IPC: A61K31/397 ,  A61N5/10 ,  A61K9/00

CPC classification number: A61K31/397 ,  A61K9/0019 ,  A61N5/10 ,  C07D205/04

Abstract: The present invention provides cyclic nitro compound, pharmaceutical compositions of cyclic nitro compounds and methods of using cyclic nitro compounds and/or pharmaceutical compositions thereof to treat or prevent diseases or disorders characterized by abnormal cell proliferation, such as cancer, inflammation, cardiovascular disease and autoimmune disease.