公开(公告)号：US07742567B2

公开(公告)日：2010-06-22

申请号：US11786759

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： One aspect relates to locating an at least one scattering event at least partially within an at least some matter of an at least a portion of an individual at least partially by directing an at least one pulse-type applied X-ray at the at least some matter of the at least the portion of the individual to create an at least one corresponding pulse-type Compton scattered X-ray, wherein the locating the at least one scattering event is based at least in part on an at least one time of flight computation derived at least in part from a combination of an at least one applied duration and an at least one scattered duration, wherein the at least one applied duration corresponds to a time for the at least one pulse-type applied X-ray to reach the at least one scattering event within the at least some matter of the at least the portion of the individual, and further wherein the at least one scattered duration corresponds to a time for the at least one corresponding pulse-type Compton scattered X-ray to thereupon travel from the at least one scattering event within the at least some matter of the at least the portion of the individual to be detected.

摘要翻译： 一个方面涉及至少部分地至少部分地至少部分地位于个体的至少一部分内的至少一个散射事件，至少部分地通过将至少一个脉冲型施加的X射线引导到至少一些 该个体的至少一部分的物质以产生至少一个对应的脉冲型康普顿散射X射线，其中定位该至少一个散射事件至少部分地基于至少一次飞行时间计算 至少部分地来自至少一个施加持续时间和至少一个散射持续时间的组合，其中所述至少一个施加的持续时间对应于所述至少一个脉冲型施加的X射线到达所述时间的时间 在所述个体的至少一部分的至少一些物质内的至少一个散射事件，并且其中所述至少一个散射持续时间对应于所述至少一个对应的脉冲型康普顿散射的时间 X射线随后从至少一个待检测个体的该部分的至少一些物质内的至少一个散射事件行进。

公开(公告)号：US07738627B2

公开(公告)日：2010-06-15

申请号：US11906156

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to determining a location of an at least one X-ray fluorescing event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the at least one X-ray fluorescing event is based at least in part on determining a relative angle at which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a relative position from which an at least one applied high energy photon and/or particle is being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one induced fluorescing X-ray photon fluoresced during the at least one X-ray fluorescing event, and a received angle at which the at least one induced fluorescing X-ray photon is received.

摘要翻译： 一个方面涉及确定发生在个体至少一部分的至少一部分内的至少一个X射线荧光事件的位置，其中确定至少一个X射线发荧光事件的位置是基于 至少部分地基于确定至少一个所施加的高能量光子和/或颗粒被施加到所述至少所述个体的所述部分中的所述至少一些物质的相对角度，相对位置至少一个 一个应用的高能量光子和/或粒子被施加到个体的至少一部分的至少一些物质，在至少一个X射线照射期间发现荧光的至少一个感应的荧光X射线光子的检测位置， 射线荧光事件和接收至少一个感应的荧光X射线光子的接收角度。

公开(公告)号：US07734012B2

公开(公告)日：2010-06-08

申请号：US11786758

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： One aspect relates to capturing one or more tomographic-type Compton scattering based visualizations, images, or provided information of an at least some matter of at least a portion of an individual based at least partially on Compton scattering of an at least one X-ray being applied to the at least some matter of the at least the portion of the individual. Another aspect relates to deriving an at least one material characteristic distribution function that substantially fits at least some data obtained at least partially by scattering of an at least one applied X-ray within at least some matter of at least a portion of an individual to form at least one Compton scattered X-ray.

摘要翻译： 一个方面涉及至少部分地至少部分地基于至少一个X射线的康普顿散射捕获一个或多个层析摄影类型的基于康普顿散射的可视化，图像或至少部分个体的提供的信息 被应用于个人的至少一部分的至少一些事物。 另一方面涉及导出至少一种材料特征分布函数，其基本上适合于至少部分地通过在个体的至少一部分的至少一部分内的至少一部分内散射至少一个施加的X射线而获得的至少一些数据，以形成 至少有一个康普顿分散的X光片。

公开(公告)号：US07724871B2

公开(公告)日：2010-05-25

申请号：US11786775

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： A61B6/483 ,  A61B6/12 ,  A61B6/145 ,  A61B6/482 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B6/548 ,  A61B18/12 ,  A61B18/20 ,  A61N7/02

摘要： A system, method, or apparatus provides information relating to at least some tissue-based matter or bone-based matter of an individual responsive to an X-ray applied to the at least some tissue-based matter or bone-based matter. In one approach, the system, method or apparatus determines information at least in part from Compton scattering principles. In one approach, the information can correspond to a range of depths or can indicate depth of features or scattering events. In one approach, the information is responsive to a determined change in direction and/or energy state of photons undergoing Compton scattering.

摘要翻译： 系统，方法或装置提供与至少一些基于组织的物质或基于骨的物质有关的信息，所述物质对应用于至少一些基于组织的物质或基于骨的物质的X射线是有反应的。 在一种方法中，系统，方法或装置至少部分地根据康普顿散射原理确定信息。 在一种方法中，信息可以对应于深度范围，或者可以指示特征或散射事件的深度。 在一种方法中，信息响应于经历康普顿散射的光子的方向和/或能量状态的确定变化。

公开(公告)号：US07702066B2

公开(公告)日：2010-04-20

申请号：US11906144

申请日：2007-09-28

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223 ,  G01N23/225

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to inducing at least one induced X-ray fluorescing photon at a X-ray fluorescence event within an at least some matter of an at least a portion of an at least one individual responsive to an at least some input energy being applied to the at least some matter of the at least the portion of the at least one individual. The aspect can include detecting the at least one induced X-ray fluorescing photon, wherein the inducing at least one induced X-ray fluorescing photon and the detecting the at least one induced X-ray fluorescing photon is configured to be transported portably as a self-contained and self-powered unit.

摘要翻译： 一个方面涉及在至少一个个体的至少一部分的至少一部分内的X射线荧光事件处诱导至少一个诱导的X射线荧光光子，所述至少一个个体响应至少一些输入能量被施加到 所述至少一个个体的至少一部分的至少一些物质。 该方面可以包括检测至少一个诱导的X射线荧光光子，其中诱导至少一个诱导的X射线荧光光子和检测至少一个诱导的X射线荧光光子被配置为作为自身移动地传输 包含和自供电单元。

公开(公告)号：US07825376B2

公开(公告)日：2010-11-02

申请号：US11906154

申请日：2007-09-28

申请人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Glenn B. Foster ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： H01J40/00 ,  H01J47/00

CPC分类号： G01N23/223 ,  G01N2223/076

摘要： One aspect relates to optically detecting an at least one scintillated viewable and/or visible photon that has been converted from the at least one induced X-ray fluorescing photon. The aspect can also relate to optically detecting an at least one scintillated viewable and/or visible photon that has been converted from the at least one induced X-ray fluorescing photon.

摘要翻译： 一个方面涉及光学检测已经从至少一个诱导的X射线荧光光子转换的至少一个闪烁的可见和/或可见光子。 该方面还可以涉及光学检测已经从至少一个诱导的X射线荧光光子转换的至少一个闪烁的可见和/或可见光子。

公开(公告)号：US07649975B2

公开(公告)日：2010-01-19

申请号：US11906151

申请日：2007-09-28

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/223

CPC分类号： G01N23/223 ,  A61B5/415 ,  A61B5/418 ,  A61B5/489 ,  A61B6/12 ,  A61B6/14 ,  A61B6/4021 ,  A61B6/4291 ,  A61B6/482 ,  A61B6/485 ,  A61B6/50 ,  A61B6/501 ,  A61B6/502 ,  A61B6/503 ,  A61B6/504 ,  A61B6/505 ,  A61B6/506 ,  A61B6/507 ,  A61B6/508 ,  A61B2503/40 ,  G01N2223/076

摘要： One aspect can relate to detecting a presence of an at least one chemical, compound, or biological material contained in an at least some matter of an at least a portion of an at least one individual based at least partially on addition of an at least one chemical identifying additive to the at least some matter of the at least the portion of the at least one individual based at least partially on a generation of an at least one induced X-ray fluorescing photon within the at least one chemical identifying additive responsive to a single input energy event in which an at least some input energy is being applied proximal to the at least one chemical, compound, or biological material contained in the at least some matter of the at least the portion of the at least one individual.

公开(公告)号：US07623625B2

公开(公告)日：2009-11-24

申请号：US11786741

申请日：2007-04-11

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Robert W. Lord ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G01N23/201

CPC分类号： G01N23/201

摘要： One aspect relates to determining a location of an at least one scattering event occurring within an at least some matter of at least a portion of an individual, wherein the determining the location of the at least one scattering event is based at least in part on a combination of: a relative position and/or angle at which an at least one applied X-ray being applied to the at least some matter of the at least the portion of the individual, an applied energy level of the at least one applied X-ray being applied to the at least some matter of the at least the portion of the individual, a detected location of an at least one scattered X-ray resulting from scattering of the at least one applied X-ray scattering during the at least one scattering event, and a scattered energy level of the at least one scattered X-ray.

摘要翻译： 一个方面涉及确定发生在个体的至少一部分的至少一部分内的至少一个散射事件的位置，其中确定至少一个散射事件的位置至少部分地基于 组合：将至少一个所施加的X射线施加到所述个体的至少一部分的至少一些物质的相对位置和/或角度，所述至少一个施加的X射线的施加能量水平， 射线被施加到个体的至少一部分的至少一些物质，在至少一个散射期间由所述至少一个施加的X射线散射的散射产生的至少一个散射X射线的检测位置 事件和至少一个散射X射线的散射能级。

公开(公告)号：US07873234B2

公开(公告)日：2011-01-18

申请号：US11598214

申请日：2006-11-09

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G01R33/565

摘要： Certain aspects can relate to obtaining at least some input compensating information at least partially based on the distortion characterizing imaging information that when applied to an imaging modality used to obtain the at least one image information can limit distortions to the at least the portion of the at least one image information resulting from at least a portion of at least one distorting feature, wherein the at least some input compensating information is characterized based at least in part on the at least one relative orientation of the at least the portion of the at least one distorting feature relative to the at least one image information.

摘要翻译： 至少部分地基于失真表征成像信息来获得至少一些输入补偿信息的某些方面可以涉及当应用于用于获得所述至少一个图像信息的成像模态时可以限制到at的至少一部分的失真 至少一个图像信息由至少一个失真特征的至少一部分产生，其中所述至少一些输入补偿信息至少部分地基于至少一个至少一个失真特征的至少一个部分的至少一个相对取向来表征 相对于至少一个图像信息的扭曲特征。

公开(公告)号：US08285073B2

公开(公告)日：2012-10-09

申请号：US13199546

申请日：2011-08-31

申请人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

发明人： Edward S. Boyden ,  Roderick A. Hyde ,  Muriel Y. Ishikawa ,  Edward K. Y. Jung ,  Eric C. Leuthardt ,  Nathan P. Myhrvold ,  Dennis J. Rivet ,  Michael A. Smith ,  Clarence T. Tegreene ,  Thomas A. Weaver ,  Charles Whitmer ,  Lowell L. Wood, Jr. ,  Victoria Y. H. Wood

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G06T5/006 ,  G06T2207/30012

摘要： Certain aspects can relate to responsive to the at least some input compensating information, imaging the at least the portion of the individual in a manner to limit at least some distorting effects of the at least the portion of the at least one distorting feature associated with the at least the portion of the individual at least partially by modifying a non-optical electromagnetic output from an imaging modality as applied to the at least the portion of the at least one distorting feature associated with the at least the portion of the individual. Certain aspects can relate to creating at least one conformal absence of a non-optical electromagnetic output to limit distortion to an imaging of an at least a portion of an individual resulting at least partially from at least one distorting feature associated with the at least the portion of the individual.

摘要翻译： 某些方面可以涉及响应于至少一些输入补偿信息，以至少限制与至少一个失真特征相关联的至少一个失真特征的至少一部分的至少一些失真效应的方式成像该个体的至少一部分 所述个体的至少一部分至少部分地通过当应用于与所述个体的至少一部分相关联的所述至少一个失真特征的所述至少一部分时，从成像模态修改非光学电磁输出。 某些方面可以涉及产生非光学电磁输出的至少一个共形缺失，以将失真限制到个体的至少一部分的成像，至少部分地由至少一个与至少部分相关联的变形特征 的个人。