公开(公告)号：US08509379B2

公开(公告)日：2013-08-13

申请号：US13360964

申请日：2012-01-30

申请人： Ute Feuerlein ,  Ernst Klotz ,  Rainer Raupach ,  Bernhard Schmidt

发明人： Ute Feuerlein ,  Ernst Klotz ,  Rainer Raupach ,  Bernhard Schmidt

IPC分类号： A61B6/00 ,  G06K9/00

CPC分类号： A61B6/032 ,  A61B6/405 ,  A61B6/481 ,  A61B6/5258 ,  A61B6/545 ,  A61B6/583 ,  G06T5/009 ,  H05G1/32

摘要： In a method and x-ray device to adapt the width and the position of a central value of a greyscale windowing for imaging with the x-ray device based on CT values determined with said x-ray device, the adaptation takes place within the scope of a determination and adjustment of an acquisition tube voltage of an x-ray tube of the x-ray device for an examination of a defined tissue of a patient, assuming a reference tube voltage for the examination of the defined tissue of the patient, and in which a width and position of a central value of the greyscale windowing that are associated with the reference tube voltage are automatically adapted to the acquisition tube voltage.

摘要翻译： 在一种方法和x射线装置中，根据由所述X射线装置确定的CT值，使用x射线装置进行成像的灰度窗口的中心值的宽度和位置调整，适应范围在 确定和调整x射线装置的X射线管的采集管电压，用于检查患者的确定的组织，假设用于检查患者的确定的组织的参考管电压，以及 其中与参考管电压相关联的灰度窗口的中心值的宽度和位置自动适应于采集管电压。

公开(公告)号：US08467587B2

公开(公告)日：2013-06-18

申请号：US12641452

申请日：2009-12-18

申请人： Corinna Bürger ,  Ernst Klotz ,  Jochen Schleu ,  Grzegorz Soza

发明人： Corinna Bürger ,  Ernst Klotz ,  Jochen Schleu ,  Grzegorz Soza

IPC分类号： G06K9/00

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/4014 ,  A61B6/4266 ,  A61B6/481 ,  A61B6/507 ,  G06T7/11 ,  G06T7/136 ,  G06T7/174 ,  G06T2207/10081 ,  G06T2207/30016

摘要： A method for distinguishing between gray matter and white matter starting from a time-dependent computed tomography image data record from a perfusion CT examination is disclosed. In at least one embodiment, a plurality of time-independent images are calculated from the time-dependent image data record, a plurality of threshold histogram analyses are performed in order to determine regions of the brain which can be assigned to one or more types of cerebral matter, and subsequently the region of gray matter is determined from the information obtained in respect of type and region of the cerebral matter using at least one logical combination and at least one exclusion method. A control and computational unit is also disclosed with a storage medium in which a computer program or program module is stored, which executes the described method during operation.

摘要翻译： 公开了从灌注CT检查的时间依赖性计算机断层摄影图像数据记录开始的区分灰质和白质的方法。 在至少一个实施例中，从时间相关图像数据记录中计算多个时间独立图像，执行多个阈值直方图分析，以便确定可分配给一个或多个类型的脑的区域 脑部物质，随后使用至少一种逻辑组合和至少一种排除方法，从关于脑物质的类型和区域获得的信息确定灰质区域。 还公开了一种其中存储有计算机程序或程序模块的存储介质的控制和计算单元，其在操作期间执行所描述的方法。

公开(公告)号：US07400756B2

公开(公告)日：2008-07-15

申请号：US10910628

申请日：2004-08-04

申请人： Ernst Klotz

发明人： Ernst Klotz

IPC分类号： G06K9/00

CPC分类号： A61B6/481 ,  A61B6/504 ,  A61B6/507 ,  G01R33/56341

摘要： A method is for calibration of perfusion parameter images. The image data from tomographic imaging measurements are analyzed using a perfusion model, and perfusion parameter values obtained from the analysis are calibrated with a calibration factor to a physiological normal value. To perform the calibration, an image area which contains several different tissue compositions, and in which approximately normal perfusion conditions can be assumed, is selected from the obtained perfusion parameter image. A frequency analysis of the perfusion parameter values contained in this image area is then performed, and at least one frequency interval is selected which corresponds at least approximately to a frequency interval of the occurrence of perfusion parameter values of a known tissue composition. A mean value is calculated from the perfusion parameter values in the frequency interval, and a comparison with the physiological normal value for this tissue composition is made in order to determine the calibration factor or a calibration value included in the calibration factor. The method permits automatic or substantially automatic calibration of perfusion parameter images.

摘要翻译： 一种用于校准灌注参数图像的方法。 使用灌注模型分析来自断层成像测量的图像数据，并且用校准因子校准从分析获得的灌注参数值至生理正常值。 为了执行校准，从所获得的灌注参数图像中选择包含几种不同组织组成并且其中可以假定近似正常灌注条件的图像区域。 然后执行包含在该图像区域中的灌注参数值的频率分析，并且选择至少一个对应于至少近似于已知组织组合物的灌注参数值的发生频率间隔的至少一个频率间隔。 根据频率间隔中的灌注参数值计算平均值，并且与该组织成分的生理正常值进行比较，以便确定校准因子或包括在校准因子中的校准值。 该方法允许灌注参数图像的自动或基本自动校准。

公开(公告)号：US20050058331A1

公开(公告)日：2005-03-17

申请号：US10910628

申请日：2004-08-04

申请人： Ernst Klotz

发明人： Ernst Klotz

IPC分类号： A61B6/03 ,  A61B6/00 ,  G01R33/563 ,  G06T1/00 ,  G06K9/00

CPC分类号： A61B6/481 ,  A61B6/504 ,  A61B6/507 ,  G01R33/56341

摘要： A method is for calibration of perfusion parameter images. The image data from tomographic imaging measurements are analyzed using a perfusion model, and perfusion parameter values obtained from the analysis are calibrated with a calibration factor to a physiological normal value. To perform the calibration, an image area which contains several different tissue compositions, and in which approximately normal perfusion conditions can be assumed, is selected from the obtained perfusion parameter image. A frequency analysis of the perfusion parameter values contained in this image area is then performed, and at least one frequency interval is selected which corresponds at least approximately to a frequency interval of the occurrence of perfusion parameter values of a known tissue composition. A mean value is calculated from the perfusion parameter values in the frequency interval, and a comparison with the physiological normal value for this tissue composition is made in order to determine the calibration factor or a calibration value included in the calibration factor. The method permits automatic or substantially automatic calibration of perfusion parameter images.

摘要翻译： 一种用于校准灌注参数图像的方法。 使用灌注模型分析来自断层成像测量的图像数据，并且用校准因子校准从分析获得的灌注参数值至生理正常值。 为了执行校准，从所获得的灌注参数图像中选择包含几种不同组织组成并且其中可以假定近似正常灌注条件的图像区域。 然后执行包含在该图像区域中的灌注参数值的频率分析，并且选择至少一个对应于至少近似于已知组织组合物的灌注参数值的发生频率间隔的至少一个频率间隔。 根据频率间隔中的灌注参数值计算平均值，并且与该组织成分的生理正常值进行比较，以便确定校准因子或包括在校准因子中的校准值。 该方法允许灌注参数图像的自动或基本自动校准。

公开(公告)号：US06647283B2

公开(公告)日：2003-11-11

申请号：US10027030

申请日：2001-12-20

申请人： Ernst Klotz

发明人： Ernst Klotz

IPC分类号： A61B505

CPC分类号： A61B6/481

摘要： In a method for examining a living subject with an imaging method making use of the concentration of a contrast agent having a physical property that is identifiable with the imaging method in a region of interest (ROI) of the subject presented in time-successive images acquired with the imaging method representing quantitative values of the physical property, a histogram of the quantitative values of the physical property in the ROI is produced for each of the individual images, and the contrast agent concentration in the ROI is determined on the basis of the frequency of occurrence of the quantitative values of the physical property in the ROI.