公开(公告)号：US20240361412A1

公开(公告)日：2024-10-31

申请号：US18643685

申请日：2024-04-23

Applicant: Case Western Reserve University

Inventor： Dan Ma ,  Zhilang Qiu

IPC: G01R33/56 ,  A61B5/055 ,  G01R33/563 ,  G01R33/565 ,  G06T3/40 ,  G06T11/00

CPC classification number: G01R33/5608 ,  A61B5/055 ,  G01R33/56341 ,  G01R33/565 ,  G06T3/40 ,  G06T11/005 ,  G06T2210/41

Abstract: A method for reconstructing images using a self-calibrated subspace reconstruction includes receiving data acquired from a subject using a magnetic resonance imaging (MRI) system, generating aliasing-free low resolution images from at least a portion of the received data using temporally local low-rank matrix completion, estimating a temporally global subspace using the aliasing-free low resolution images, and generating aliasing-free high resolution images from the received data using temporally global subspace reconstruction that utilizes the estimated temporally global subspace. In some embodiments, a customized outlier detection algorithm can then be used to detect measurement errors in the aliasing-free high resolution images and to correct the aliasing-free high resolution images. Aliasing-free T1, T2, and ADC maps may be generated after comparing the corrected aliasing free high resolution images with a dictionary.

公开(公告)号：US20240331157A1

公开(公告)日：2024-10-03

申请号：US18744328

申请日：2024-06-14

Applicant: Omniscient Neurotechnology Pty Limited

Inventor： Michael Edward Sughrue ,  Stephane Philippe Doyen ,  Charles Teo

IPC: G06T7/00 ,  G01R33/56 ,  G01R33/563 ,  G06T7/30

CPC classification number: G06T7/0014 ,  G01R33/5608 ,  G01R33/56341 ,  G06T7/30 ,  G06T2207/10088 ,  G06T2207/20076 ,  G06T2207/20081 ,  G06T2207/30016

Abstract: A method (400) including: determining (702) a registration function [705, Niirf(T1)] for the particular brain in a coordinate space, determining (706) a registered atlas [708, Ard(T1)] from the registration function and an HCP-MMP1 Atlas (102) containing a standard parcellation scheme, performing (310, 619) diffusion tractography to determine a set [621, DTIp(DTI)] of brain tractography images of the particular brain, for a voxel in a particular parcellation in the registered atlas, determining (1105, 1120) voxel level tractography vectors [1123, Vje, Vjn] showing connectivity of the voxel with voxels in other parcellations, classifying (1124) the voxel based on the probability of the voxel being part of the particular parcellation, and repeating (413) the determining of the voxel level tractography vectors and the classifying of the voxels for parcellations of the HCP-MMP1 Atlas to form a personalised brain atlas [1131, PBs Atlas] containing an adjusted parcellation scheme reflecting the particular brain (Bbp).

公开(公告)号：US20240295620A1

公开(公告)日：2024-09-05

申请号：US18573518

申请日：2022-06-27

Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS

Inventor： Xiaohong Joe Zhou ,  Kaibao Sun

IPC: G01R33/483 ,  G01R33/48 ,  G01R33/561 ,  G01R33/563

CPC classification number: G01R33/4835 ,  G01R33/4806 ,  G01R33/4822 ,  G01R33/4836 ,  G01R33/5611 ,  G01R33/5616 ,  G01R33/56341

Abstract: The present disclosure provides technologies that allow reduced field of view or fast imaging with reduced image distortion. The first technique capitalizes on the benefit of reduced field of view imaging for full field of view coverage. The second technique allows achieves high resolution 3D images in a focused region. These techniques are expected to have applications for cancer imaging, neuro imaging, and other biomedical imaging areas.

公开(公告)号：US12048553B2

公开(公告)日：2024-07-30

申请号：US16848244

申请日：2020-04-14

Applicant: The Government of the United States of America, as represented by the Secretary of the Navy

Inventor： Anthony J Romano ,  William G. Szymczak

IPC: A61B5/00 ,  A61B5/055 ,  G01R33/30 ,  G01R33/50 ,  G01R33/56 ,  G01R33/563

CPC classification number: A61B5/4064 ,  A61B5/0042 ,  A61B5/055 ,  G01R33/30 ,  G01R33/50 ,  G01R33/5608 ,  G01R33/56341

Abstract: Systems and methods are provided for medical diagnosis and analysis using mixed model inversions. For example, a medical analyzer using mixed model inversions according to an embodiment of the present disclosure can be used to diagnose traumatic brain injury (TBI), which allows for isotropic and anisotropic inversions to be performed, enabling more accurate information about brain stiffness to be obtained.

公开(公告)号：US20240241104A1

公开(公告)日：2024-07-18

申请号：US18622012

申请日：2024-03-29

Applicant: Axogen Corporation

Inventor： Curt DEISTER

IPC: G01N33/483 ,  G01N33/50 ,  G01N33/569 ,  G01R33/56 ,  G01R33/563

CPC classification number: G01N33/4833 ,  G01N33/5026 ,  G01N33/56966 ,  G01R33/5608 ,  G01R33/56341

Abstract: Techniques and systems are disclosed for a bioassay that is an in vitro mimic of peripheral nerve generation using the sensory neurons that innervate the peripheral nervous system. In some embodiments, the techniques may assist in detecting the bioactivity or potency of nerve grafts (e.g., processed, acellular human allografts) for fostering or supporting peripheral nerve regeneration. In various embodiments, techniques comprise affixing a harvested sensory neuron (e.g., a DRG) to a nerve graft segment to form a test construct; culturing the test construct in a medium; analyzing the test construct to indicate the amount of outgrowing peripheral nerve structure; and determining the potency of the nerve graft from a metric derived from the analysis. In some embodiments, techniques and materials may be used to test the effect of a varied test condition on peripheral nerve growth.

公开(公告)号：US20240192299A1

公开(公告)日：2024-06-13

申请号：US18079147

申请日：2022-12-12

Applicant: GE Precision Healthcare LLC

Inventor： Hua Li ,  Lei Gao ,  Gaohong Wu

IPC: G01R33/565 ,  G01R33/48 ,  G01R33/563

CPC classification number: G01R33/56518 ,  G01R33/4818 ,  G01R33/56341

Abstract: A method for correcting diffusion-weighted echo-planar imaging data (DW-EPI) includes obtaining a first reference scan with no diffusion gradients applied, a second reference scan with a diffusion gradient applied only along a frequency direction, a third reference scan with the diffusion gradient applied only along a phase direction, and a fourth reference scan with the diffusion gradient applied only along a slice direction acquired utilizing an MRI scanner, wherein the reference scans lack phase encoding. The method includes obtaining DW-EPI data acquired utilizing the MRI scanner, wherein the DW-EPI data includes phase errors due to oscillatory eddy currents causing time-varying Bo shift. The method includes generating a phase correction factor based on the reference scans and correcting the phase errors due to the oscillatory eddy currents in the DW-EPI data independent of diffusion gradient direction utilizing the phase correction factor to generate corrected DW-EPI data.

公开(公告)号：US20240175957A1

公开(公告)日：2024-05-30

申请号：US18462487

申请日：2023-09-07

Applicant: Mint Labs Inc.

Inventor： Vesna Prchkovska ,  Paulo Reis Rodrigues ,  Matthew Rowe

IPC: G01R33/563 ,  A61B5/00 ,  A61B5/055 ,  G01R33/56 ,  G06T7/00 ,  G06T7/11 ,  G06T7/143 ,  G16H30/40 ,  G16H40/63

CPC classification number: G01R33/56341 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0042 ,  A61B5/055 ,  G01R33/5608 ,  G06T7/0012 ,  G06T7/11 ,  G06T7/143 ,  G16H30/40 ,  A61B2576/026 ,  G06T2207/10092 ,  G06T2207/30016 ,  G16H40/63

Abstract: The present solution can segment tracts by performing two-pass tractography. The system can first perform deterministic tractography and then probabilistic tractography. The system can use the result from the deterministic tractography to update and refine initial identified regions of interest. The refined regions of interest can be used to filter and select streamlines identified through the probabilistic tractography.

公开(公告)号：US11963752B2

公开(公告)日：2024-04-23

申请号：US16798265

申请日：2020-02-21

Applicant: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.

Inventor： Jingyuan Lyu ,  Qi Liu ,  Zhongqi Zhang ,  Jian Xu

IPC: A61B5/055 ,  A61B6/00 ,  A61B6/03 ,  G01R33/24 ,  G01R33/46 ,  G01R33/48 ,  G01R33/483 ,  G01R33/561 ,  G01R33/563 ,  G01R33/565 ,  G06T3/00 ,  G06T7/00 ,  G06T7/215 ,  G06T7/262 ,  G06T7/269 ,  G06T9/00 ,  G06T11/00

CPC classification number: A61B5/055 ,  G01R33/4616 ,  G01R33/4818 ,  G01R33/561 ,  G01R33/56316 ,  G01R33/56563 ,  G01R33/5659 ,  G06T7/0016 ,  G06T9/008 ,  G06T11/003 ,  G06T11/005 ,  G06T11/008 ,  A61B6/032 ,  A61B6/5205 ,  G01R33/243 ,  G01R33/4833 ,  G01R33/5611 ,  G01R33/5617 ,  G01R33/5618 ,  G01R33/5619 ,  G01R33/56341 ,  G06T3/0087 ,  G06T7/0012 ,  G06T7/215 ,  G06T7/262 ,  G06T7/269 ,  G06T2207/10072 ,  G06T2207/10084 ,  G06T2207/10088 ,  G06T2207/10092 ,  G06T2207/10096 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/10132 ,  G06T2207/10136 ,  G06T2207/20182 ,  G06T2207/30004 ,  G06T2207/30048 ,  G06T2210/41 ,  G06T2210/52 ,  G06T2211/40 ,  G06T2211/416

Abstract: An imaging method may include obtaining imaging data associated with a region of interest (ROI) of an object. The imaging data may correspond to a plurality of time-series images of the ROI. The imaging method may also include determining, based on the imaging data, a data set including a spatial basis and one or more temporal bases. The spatial basis may include spatial information of the imaging data. The one or more temporal bases may include temporal information of the imaging data. The imaging method may also include storing, in a storage medium, the spatial basis and the one or more temporal bases.

公开(公告)号：US11874360B2

公开(公告)日：2024-01-16

申请号：US17698899

申请日：2022-03-18

Applicant: Stephan Ernst Maier ,  Stefan Kuczera

Inventor： Stephan Ernst Maier ,  Stefan Kuczera

IPC: G01R33/563 ,  G01R33/56

CPC classification number: G01R33/56341 ,  G01R33/5602 ,  G01R33/5608

Abstract: The present invention relates to parameter quantification for reproducible characterization of measured magnetic resonance signal variations in biological tissues due to variation in contrast-weighting levels. The method uses comprehensive sampling and higher-order model analysis to attain a more complete description of the signal variation at high signal-to-noise ratio. The signal variation described by the higher-order model fit is subsequently used for retrospective fit analysis based on a more basic model and a flexible sampling pattern. This approach greatly facilitates reproducibility of parameter quantification, since sampling inconsistencies can readily be accounted for.

公开(公告)号：US20230393224A1

公开(公告)日：2023-12-07

申请号：US18206664

申请日：2023-06-07

Applicant: Siemens Healthcare GmbH

Inventor： Stefan Popescu

IPC: G01R33/563 ,  G01R33/383 ,  G01R33/54 ,  G01R33/385 ,  G01R33/34

CPC classification number: G01R33/56341 ,  G01R33/383 ,  G01R33/34084 ,  G01R33/385 ,  G01R33/543

Abstract: A magnetic resonance system configured to acquire magnetic resonance data of an object in an field-of-view, wherein the magnetic resonance system includes a magnet that is configured such that it creates a gradient field at the field-of-view; a controller configured to cause the magnetic resonance system to utilize the magnet's gradient field for diffusion weighted imaging or mixed contrast imaging; and a unit of one or several RF coils, wherein the RF coils are configured to acquire magnetic resonance data from the object and to support or flexibly attach to the patient body.