公开(公告)号：US11858995B2

公开(公告)日：2024-01-02

申请号：US17559935

申请日：2021-12-22

Applicant: GENMAB A/S

Inventor： Brian Elliott ,  Jenny Jianlin Chen ,  Tahamtan Ahmadi ,  Christopher W. L. Chiu ,  Esther C. W. Breij ,  Ida Hiemstra ,  Maria N. Jure-Kunkel

IPC: A61K39/00 ,  C07K16/28

CPC classification number: C07K16/2809 ,  C07K16/2887 ,  A61K2039/507 ,  A61K2039/545 ,  C07K2317/24 ,  C07K2317/31

Abstract: Provided are methods of clinical treatment of chronic lymphoblastic leukemia (CLL) in human subjects using a bispecific antibody which binds to CD3 and CD20.