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公开(公告)号：US10968280B2
公开(公告)日：2021-04-06
申请号：US16779011
申请日：2020-01-31
Applicant: GENMAB A/S , BIONTECH SE
Inventor： Isil Altintas , David Satijn , Rik Rademaker , Paul Parren , Ugur Sahin , Friederike Gieseke , Alexander Muik , Christian Grunwitz
IPC: C07K16/28
Abstract: The present invention relates to novel binding agents and their use in medicine. In particular, the invention relates to binding agents such as bispecific antibodies binding human PD-L1 and binding human CD137. The invention furthermore relates to uses of the antibodies of the invention and to methods, nucleic acid constructs and host cells for producing antibodies of the invention.
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公开(公告)号：US20200079866A1
公开(公告)日：2020-03-12
申请号：US16582534
申请日：2019-09-25
Applicant: BIONTECH SE , GENMAB A/S
Inventor： Ugur Sahin , Friederike Gieseke , Isil Altintas , David Satijn , Paul Parren
IPC: C07K16/28
Abstract: The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.
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公开(公告)号：US10544220B2
公开(公告)日：2020-01-28
申请号：US15541594
申请日：2016-01-08
Applicant: GENMAB A/S
Inventor： Patrick Engelberts , Esther Breij , Rik Rademaker , Isil Altintas , David Satijn , Sandra Verploegen , Riemke Van Dijkhuizen Radersma , Edward Van Den Brink , Janine Schuurman , Paul Parren
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K39/00
Abstract: Bispecific antibodies directed to CD3 and CD20 and uses of such bispecific antibodies, in particular use thereof in the treatment of diseases in which specific targeting and T cell-mediated killing of cells that express CD20 is desired.
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公开(公告)号：US12077596B2
公开(公告)日：2024-09-03
申请号：US17360438
申请日：2021-06-28
Applicant: GENMAB A/S , BioNTech SE
Inventor： Isil Altintas , David Satijn , Rik Rademaker , Paul Parren , Friederike Gieseke , Ugur Sahin
IPC: C07K16/28 , A61K39/395 , G01N33/569
CPC classification number: C07K16/2878 , A61K39/3955 , G01N33/56972 , C07K2317/24 , C07K2317/31 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/565 , C07K2317/92
Abstract: Multispecific antibodies binding to human CD40 and human CD137, methods for preparing such multispecific antibodies, and methods of using such multispecific antibodies for therapeutic or other purposes.
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公开(公告)号：US11939388B2
公开(公告)日：2024-03-26
申请号：US17360437
申请日：2021-06-28
Applicant: GENMAB A/S , BioNTech SE
Inventor： Isil Altintas , David Satijn , Rik Rademaker , Paul Parren , Friederike Gieseke , Ugur Sahin
IPC: C07K16/28 , A61K39/395 , G01N33/569
CPC classification number: C07K16/2878 , A61K39/3955 , G01N33/56972 , C07K2317/24 , C07K2317/31 , C07K2317/524 , C07K2317/526 , C07K2317/53 , C07K2317/565 , C07K2317/92
Abstract: Multispecific antibodies binding to human CD40 and human CD137, methods for preparing such multispecific antibodies, and methods of using such multispecific antibodies for therapeutic or other purposes.
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Patent Agency Ranking
公开(公告)号：US20230027394A1
公开(公告)日：2023-01-26
申请号：US17739934
申请日：2022-05-09
Applicant: GENMAB A/S
Inventor： Rik RADEMAKER , Isil Altintas , Patrick Engelberts , Janine Schuurman , Paul Parren
Abstract: The present invention relates to humanized or chimeric antibodies binding CD3. It furthermore relates to bispecific antibodies, compositions, pharmaceutical compositions, use of said antibodies in the treatment of a disease, and method of treatment.
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公开(公告)号：US11440966B2
公开(公告)日：2022-09-13
申请号：US17345628
申请日：2021-06-11
Applicant: GENMAB A/S , BioNTech SE
Inventor： Isil Altintas , David Satijn , Rik Rademaker , Paul Parren , Friederike Gieseke , Ugur Sahin
IPC: C07K16/28 , A61K39/395 , G01N33/569
Abstract: Multispecific antibodies binding to human CD40 and human CD137, methods for preparing such multispecific antibodies, and methods of using such multispecific antibodies for therapeutic or other purposes.
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公开(公告)号：US11091557B2
公开(公告)日：2021-08-17
申请号：US16316534
申请日：2017-07-14
Applicant: GENMAB A/S , BioNTech SE
Inventor： Isil Altintas , David Satijn , Rik Rademaker , Paul Parren , Friederike Gieseke , Ugur Sahin
IPC: A61K39/395 , C07K16/28 , G01N33/569
Abstract: Multispecific antibodies binding to human CD40 and human CD137, methods for preparing such multispecific antibodies, and methods of using such multispecific antibodies for therapeutic or other purposes.
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公开(公告)号：US10927181B2
公开(公告)日：2021-02-23
申请号：US16582534
申请日：2019-09-25
Applicant: BIONTECH SE , GENMAB A/S
Inventor： Ugur Sahin , Friederike Gieseke , Isil Altintas , David Satijn , Paul Parren
IPC: C07K16/28
Abstract: The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.
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公开(公告)号：US20180194849A1
公开(公告)日：2018-07-12
申请号：US15538419
申请日：2016-01-08
Applicant: BIONTECH AG , GENMAB A/S
Inventor： Ugur Sahin , Friederike Gieseke , Isil Altintas , David Satijn , Paul Parren
IPC: C07K16/28
Abstract: The present invention relates to binding agents binding to receptors of the TNF superfamily, in particular binding agents binding to at least two different receptors of the TNF superfamily, as well as to their use in medicine. The present invention further relates to nucleic acid molecules encoding such binding agents, to cells comprising such nucleic acid molecules and to pharmaceutical compositions and kits.
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