公开(公告)号：US20150051260A1

公开(公告)日：2015-02-19

申请号：US14388671

申请日：2013-04-11

Applicant: GEORGETOWN UNIVERSITY

Inventor： Jeffrey A. Toretsky ,  Milton Lang Brown ,  Perrer N. Tosso ,  Aykut Uren ,  Yali Kong

IPC: C07D209/38 ,  C07D209/34

CPC classification number: C07D209/38 ,  C07D209/34

Abstract: Compounds, compositions and methods relating to EWS-FLI1 protein inhibitors are provided. The compounds have utility in the treatment of cancers including the Ewing's sarcoma family of tumors.

Abstract translation: 提供了与EWS-FLI1蛋白抑制剂有关的化合物，组合物和方法。 该化合物可用于治疗包括尤文氏肉瘤肿瘤家族在内的癌症。