公开(公告)号：US20170369430A1

公开(公告)日：2017-12-28

申请号：US15694303

申请日：2017-09-01

Applicant: GRI BIO, INC.

Inventor： Georg Schlechtingen ,  Hans-Joachim Knolker ,  Tim Friedrichson ,  Gary Jennings ,  Tobias Braxmeier

IPC: C07C309/14 ,  A61K31/205

Abstract: The present invention relates to oxygenated amino or ammonium-containing sulfonic acid, phosphoric acid and carboxylic acid derivatives, in particular the compounds of formula 1, 2, 3, 4, 5 or 6, and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dys-plastic disease or disorder.

公开(公告)号：US20170157070A1

公开(公告)日：2017-06-08

申请号：US15436678

申请日：2017-02-17

Applicant: GRI BIO, INC.

Inventor： Georg Schlechtingen ,  Hans-Joachim Knolker ,  Tim Friedrichson ,  Gary Jennings ,  Tobias Braxmeier

IPC: A61K31/164 ,  A61K45/06

CPC classification number: C07C237/08 ,  A61K31/164 ,  A61K45/06

Abstract: The present invention relates to hydroxy-substituted amino and ammonium derivatives, in particular the compounds of formula (1) or (2), and their medical use, including their use in the treatment, prevention or amelioration of an inflammatory, autoimmune and/or allergic disorder, or a proliferative, neoplastic or dysplastic disease or disorder.