公开(公告)号：US10544198B2

公开(公告)日：2020-01-28

申请号：US15454662

申请日：2017-03-09

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Xiaoting Wang ,  Ganesh A. Kolumam ,  Wyne P. Lee

IPC: C07K14/54 ,  C07K16/28 ,  A61K38/20 ,  A61K47/38 ,  A61K38/00

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.

公开(公告)号：US09815880B2

公开(公告)日：2017-11-14

申请号：US15217790

申请日：2016-07-22

Applicant: Genentech, Inc.

Inventor： Justin Scheer ,  Wenjun Ouyang ,  Richard Vandlen ,  Philip E. Hass ,  Eric Gary Stefanich ,  Xiaoting Wang

IPC: A61K38/20 ,  C07K14/54 ,  C07K16/28 ,  A61K47/38 ,  A61K38/00

CPC classification number: C07K14/54 ,  A61K38/00 ,  A61K38/20 ,  A61K47/38 ,  C07K16/2866 ,  C07K2319/30

Abstract: The invention relates to IL-22 polypeptides, IL-22 Fc fusion proteins and IL-22 agonists, composition comprising the same, methods of making and methods of using the composition for the treatment of diseases. The invention also relates to IL-22 receptor associated reagents and methods of use thereof.