公开(公告)号：US4009212A

公开(公告)日：1977-02-22

申请号：US602767

申请日：1975-08-07

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/04 ,  C07C39/06

CPC classification number: C07C37/04

Abstract: A process for the preparation of dihydroxybenzenes whereby there are obtained primarily meta isomers of the dihydroxybenzenes includes the steps of: preparing a mixture of sulfonic acid isomers by sulfonation-isomerization of an hydroxybenzene having the formula: ##STR1## in which R and R' are selected from the group consisting of hydrogen and an alkyl radical having at most 4 carbon atoms per molecule, the total carbon atoms in radicals R and R' being at most 4; subjecting the so-produced sulfonic acids to selective hydrolyzation in aqueous medium at a temperature between about 100.degree. and 150.degree. C., the monohydroxy benzene being recovered by the said selective hydrolyzation in an enriched concentration that makes it readily recoverable by recycle in the process or other separation methods, and unhydrolyzed sulfonic acid remaining in the said aqueous medium; caustically fusing the said unhydrolyzed sulfonic acid, and liberating by acidification the desired dihydroxybenzene.

公开(公告)号：US4469900A

公开(公告)日：1984-09-04

申请号：US567957

申请日：1984-01-04

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C39/26 ,  C07C39/24

CPC classification number: C07C37/86 ,  C07C39/44

Abstract: A process is disclosed for separating closely-boiling chlorinated phenolic compounds from other chlorinated and unchlorinated phenolics by treating a mixture of the phenolics with a metal halide salt. The metal halide salt preferentially forms a complex with one of the phenolics over other related closely-boiling phenolics in the mixture. The preferentially-formed complex of one of the phenolics may then be isolated from the mixture and the complex decomposed to provide a product substantially enriched in, or substantially entirely composed of, one phenolic. The process is particularly suitable for resolving a mixture comprising phenol or cresol from their closely-boiling ortho-chlorinated derivatives, or a mixture of two isomeric chlorinated phenols or cresols or a mixture of closely-boiling mono- and dichlorinated phenols or cresols.

Abstract translation: 公开了通过将酚类与金属卤化物盐的混合物进行处理来分离紧密沸腾的氯化酚类化合物与其它氯化和未氯化酚类物质的方法。 与混合物中其它相关的紧密沸腾的酚类物质相比，金属卤化物盐优先与酚类之一形成络合物。 然后可以从混合物中分离一种酚类的优先形成的络合物，并且复合物被分解以提供基本上富含或完全由一种酚类组成的产物。 该方法特别适用于从其接近沸腾的邻氯离子衍生物或两种异构氯化酚或甲酚的混合物或紧密沸腾的单氯和二氯酚或甲酚的混合物中分离出包含苯酚或甲酚的混合物。

公开(公告)号：US4431846A

公开(公告)日：1984-02-14

申请号：US381159

申请日：1982-05-24

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C37/68

CPC classification number: C07C37/86

Abstract: A process is disclosed for reducing the concentration of o-ethylphenol in m,p-cresol by partially t-butylating a mixture of the above and equilibrating the resultant mixture to convert o-ethylphenol and its 6-t-butyl derivative to the thermodynamically most stable 4-t-butyl-o-ethylphenol. The resultant mixture may then be separated by fractional distillation to isolate m,p-cresol low in o-ethylphenol, optionally, the mono-t-butylated derivatives of m,p-cresol and leave behind the 4-t-butyl-o-ethylphenol, along with di-t-butylated derivatives of all the phenols.

Abstract translation: 公开了一种通过部分叔丁基化上述混合物并平衡所得混合物以将邻乙基苯酚及其6-叔丁基衍生物转化为热力学最大的方法，以减少m，对甲酚中的邻乙基苯酚的浓度的方法 稳定的4-叔丁基邻乙基苯酚。 然后可通过分馏分离得到的混合物，以将邻甲基苯酚中的间甲酚，对甲酚低，任选地，m，对甲酚的单叔丁基化衍生物，并留在4-叔丁基邻 - 乙基苯酚，以及所有酚类的二叔丁基化衍生物。

公开(公告)号：US4267389A

公开(公告)日：1981-05-12

申请号：US53438

申请日：1979-06-29

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C37/68

CPC classification number: C07C37/86 ,  C07C37/685 ,  C07C37/84

Abstract: Para-cresol is separated from a mixture comprising meta-cresol and various other methylated and ethylated phenols by preferentially complexing the para-cresol with one or more anhydrous or dehydrated inorganic salts selected from the group consisting of calcium bromide, lithium bromide, manganese bromide and magnesium chloride. The anhydrous inorganic salt is added to the phenolic mixture in an amount to give a mole ratio of salt to para-cresol in the mixture in the range of about 0.5 mole to one to about 1.5 mole to one. The para-cresol and salt form a complex and the complex is removed from the mixture of methylated and ethylated phenols. Then the complex is decomposed to recover the para-cresol and salt; the recovered salt may be recycled to complex with more para-cresol.

Abstract translation: 通过优选地将对甲酚与一种或多种选自溴化钙，溴化锂，溴化锰的无水或脱水的无机盐优先络合，将对甲酚与包含间甲酚和各种其它甲基化和乙基化酚的混合物分离， 氯化镁。 将无水无机盐加入到酚类混合物中，其量使混合物中盐与对甲酚的摩尔比在约0.5摩尔至1至约1.5摩尔的范围内。 对甲酚和盐形成络合物，并从甲基化和乙基化酚的混合物中除去络合物。 然后将复合物分解以回收对甲酚和盐; 回收的盐可以被再循环以与更多的对甲酚复合。

公开(公告)号：US4158101A

公开(公告)日：1979-06-12

申请号：US787891

申请日：1977-04-15

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/11 ,  C07C37/12 ,  C07C39/06

CPC classification number: C07C37/11

Abstract: Phenolic compounds are methylated with methane in the presence of a metallic catalyst selected from nickel or cobalt or mixtures thereof at a temperature in the range of about 300.degree. C. to around 475.degree. C.

Abstract translation: 在约300℃至约475℃的温度范围内，在选自镍或钴的金属催化剂或其混合物的存在下，将甲苯化甲烷化为甲烷。

公开(公告)号：US4046818A

公开(公告)日：1977-09-06

申请号：US590458

申请日：1975-06-26

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C37/22 ,  C07C39/06

CPC classification number: C07C37/86 ,  C07C2101/14

Abstract: A 3,5-dialkylphenol having alkyl groups that are primary or secondary and that have a sum total of carbon atoms greater than two is separated from a mixture which also contains other dialkylphenols and mono-alkylphenols. The mixture is subjected to a selective sulfonation in order that all the compounds in the mixture, except the 3,5-dialkylphenol, are sulfonated. Then, the unsulfonated 3,5-dialkylphenol and the sulfonated compounds are separated, and the purified 3,5-dialkylphenol is recovered.

Abstract translation: 具有伯或仲二级并具有大于2的碳原子总和的3,5-二烷基苯酚与还含有其它二烷基酚和单烷基酚的混合物分离。 将混合物进行选择性磺化，以使除3,5-二烷基苯酚以外的混合物中的所有化合物都被磺化。 然后，分离未磺化的3,5-二烷基苯酚和磺化化合物，回收纯化的3,5-二烷基苯酚。

公开(公告)号：US4480140A

公开(公告)日：1984-10-30

申请号：US475719

申请日：1983-03-16

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/00 ,  C07C37/62 ,  C07C39/06

CPC classification number: C07C37/62 ,  C07C37/00 ,  C07C37/50

Abstract: Phenols alkylated in the ortho and/or para positions are produced in good yields and in the absence of isomers from phenolic compounds having at least two alkylateable ortho-ortho or ortho-para positions open. The phenolic compound is first partially chlorinated or brominated and the desired halogenated phenol having at least one open position ortho or para is reacted with an aldehyde having one to four carbon atoms and a secondary non-aromatic amine. The reaction is conducted in the liquid phase with a stoichiometric amount of the phenolic compound and stoichiometric or excess of stoichiometric amounts of the aldehyde and the amine. The reaction is performed at a temperature of from about 0.degree. C. to about 100.degree. C. to produce an aminoalkylated halogenated phenolic compound. This aminoalkylated halogenated phenolic compound is contacted with hydrogen in the presence of a metal catalyst at a temperature of about 100.degree. C. to about 175.degree. C. and at a hydrogen pressure of less than 500 psig to produce the desired phenol having at least one alkyl group ortho or para and at least one open position ortho or para.

Abstract translation: 在邻位和/或对位烷基化的酚以良好的产率生产，并且在不存在具有至少两个可烷基化的邻位或邻位对位的酚类化合物的情况下不存在异构体。 酚类化合物首先被部分氯化或溴化，并且具有至少一个开放位置邻位或对位的所需卤代苯酚与具有1-4个碳原子的醛和仲非芳族胺反应。 反应在液相中以化学计量的酚类化合物和化学计量或过量的化学计量的醛和胺进行。 反应在约0℃至约100℃的温度下进行，以产生氨基烷基化的卤化酚类化合物。 该氨基烷基化的卤化酚类化合物在金属催化剂存在下，在约100℃至约175℃的温度和小于500psig的氢气压力下与氢气接触，以产生具有至少一个 烷基邻位或对位和至少一个开放位置邻位或对位。

公开(公告)号：US4469901A

公开(公告)日：1984-09-04

申请号：US567791

申请日：1984-01-03

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C39/06 ,  C07C201/16 ,  C07C205/22

CPC classification number: C07C37/86 ,  C07C37/84 ,  C07C39/235

Abstract: A process is disclosed for separating 5-isopropyl-m-cresol from other isopropylated m-cresols by treating a mixture of the isopropylated m-cresols with a metal halide salt. The metal halide salt preferentially forms a complex with 5-isopropyl-m-cresol over other related closely-boiling isopropylated m-cresols in the mixture. The preferentially-formed complex of 5-isopropyl-m-cresol may then be isolated from the mixture and the complex decomposed to provide a product substantially enriched in, or substantially entirely composed of, 5-isopropyl-m-cresol. The process is particularly suitable for isolating 5-isopropyl-m-cresol from closely-boiling isomers, and di-isopropylated m-cresols.

Abstract translation: 公开了通过将异丙基化间甲酚与金属卤化物盐的混合物进行处理从其它异丙基化间甲酚中分离5-异丙基间甲酚的方法。 与其他相关的沸点相近的异丙基化间甲酚相比，金属卤化物盐与5-异丙基间甲酚优先形成络合物。 然后可以从混合物中分离出优先形成的5-异丙基间甲酚的复合物，并将络合物分解，得到基本上富含或完全由5-异丙基间甲酚组成的产物。 该方法特别适用于从紧密沸腾的异构体和二异丙基化的间甲酚中分离出5-异丙基间甲酚。

公开(公告)号：US4429168A

公开(公告)日：1984-01-31

申请号：US372060

申请日：1982-04-26

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C37/68

CPC classification number: C07C37/86 ,  C07C37/685 ,  C07C37/84

Abstract: A process is disclosed for separating closely-boiling chlorinated phenolic compounds from other chlorinated and unchlorinated phenolics by treating a mixture of the phenolics with a metal halide salt. The metal halide salt preferentially forms a complex with one of the phenolics over other related closely-boiling phenolics in the mixture. The preferentially-formed complex of one of the phenolics may then be isolated from the mixture and the complex decomposed to provide a product substantially enriched in, or substantially entirely composed of, one phenolic. The process is particularly suitable for resolving a mixture comprising phenol or cresol from their closely-boiling ortho-chlorinated derivatives, or a mixture of two isomeric chlorinated phenols or cresols or a mixture of closely-boiling mono- and dichlorinated phenols or cresols.

Abstract translation: 公开了通过将酚类与金属卤化物盐的混合物进行处理来分离紧密沸腾的氯化酚类化合物与其它氯化和未氯化酚类物质的方法。 与混合物中其它相关的紧密沸腾的酚类物质相比，金属卤化物盐优先与酚类之一形成络合物。 然后可以从混合物中分离一种酚类的优先形成的络合物，并且复合物被分解以提供基本上富含或完全由一种酚类组成的产物。 该方法特别适用于从其接近沸腾的邻氯离子衍生物或两种异构氯化酚或甲酚的混合物或紧密沸腾的单氯和二氯酚或甲酚的混合物中分离出包含苯酚或甲酚的混合物。

公开(公告)号：US4423253A

公开(公告)日：1983-12-27

申请号：US372056

申请日：1982-04-26

Applicant: Gerd Leston

Inventor： Gerd Leston

IPC: C07C37/86 ,  C07C37/68

CPC classification number: C07C37/86 ,  C07C37/685 ,  C07C37/84

Abstract: A process is disclosed for separating t-butylated phenolic compounds from other t-butylated and unbutylated phenolics by treating a mixture of the phenolics with a metal halide salt. The metal halide salt preferentially forms a complex with one of the phenolics over other related phenolics in the mixture. The preferentially-formed complex of one of the phenolics may then be isolated from the mixture and the complex decomposed to provide a product substantially enriched in, or substantially entirely composed of, one phenolic. The process is particularly suitable for resolving a mixture comprising phenol or cresol from their ortho-t-butylated derivatives, or a mixture of two isomeric t-butylated phenols or cresols or a mixture of mono- and di-t-butylated phenols or cresols.

Abstract translation: 公开了通过将酚类与金属卤化物盐的混合物进行处理来分离叔丁基化酚类化合物与其它叔丁基化和未丁基化酚类的方法。 与混合物中的其它相关酚类物质相比，金属卤化物盐优先与酚类之一形成络合物。 然后可以从混合物中分离一种酚类的优先形成的络合物，并且复合物被分解以提供基本上富含或完全由一种酚类组成的产物。 该方法特别适用于从其叔丁基化衍生物或两种异构叔丁基化酚或甲酚的混合物或单 - 和二 - 叔丁基化酚或甲酚的混合物中分离出包含苯酚或甲酚的混合物。