公开(公告)号：US10087232B2

公开(公告)日：2018-10-02

申请号：US14773349

申请日：2014-03-06

Applicant: Protalix Ltd. ,  Hadasit Medical Research Services and Development Ltd.

Inventor： Yaron Ilan ,  Yoseph Shaaltiel ,  Uri Hanania ,  Tali Kizhner ,  Tami Ariel ,  Svetlana Gingis-Velitski

IPC: A61K39/00 ,  A61K38/00 ,  A61K38/16 ,  C07K14/705 ,  C07K14/525 ,  C12N15/82 ,  A61K9/00 ,  A61K36/81 ,  C07K16/24

Abstract: A method of treating a TNF Alpha associated medical condition selected from the group consisting of obesity, metabolic syndrome, diabetes and a liver disease or disorder is provided. The method comprising enterally administering to a subject in need thereof a therapeutically effective amount of plant cells expressing a TNF Alpha polypeptide inhibitor, thereby treating the TNF Alpha associated medical condition.

公开(公告)号：US09603820B2

公开(公告)日：2017-03-28

申请号：US14936153

申请日：2015-11-09

Applicant: Northwestern University ,  Hadasit Medical Research Services and Development Ltd.

Inventor： Richard B. Silverman ,  Yaron Ilan

IPC: A61K31/19 ,  A61K31/196

CPC classification number: A61K31/196

Abstract: Therapeutic methods relating to the use of GABA-AT inhibitor compounds for the treatment of hepatocellular carcinoma.