公开(公告)号：US20080214945A1

公开(公告)日：2008-09-04

申请号：US11832153

申请日：2007-08-01

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Harold Wade ,  Myrtis Randolph ,  Lori Palmquist

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Harold Wade ,  Myrtis Randolph ,  Lori Palmquist

IPC分类号： A61B5/0402

CPC分类号： A61B5/046 ,  A61B5/7264 ,  A61B5/7425 ,  A61B2576/023

摘要： A method and system for atrial fibrillation analysis, characterization, and mapping is disclosed. A finite element model (FEM) representing a physical structure of a heart is generated. Electrogram data can be sensed at various locations in the heart using an electrophysiology catheter, and the electrogram data is mapped to the elements of the FEM. Function parameters, which measure some characteristics of AF arrhythmia, are then simultaneously calculated for all of the elements of the FEM based on the electrogram data mapped to the elements of the FEM. An artificial neural network (ANN) can be used to calculate the function parameters.

摘要翻译： 公开了一种用于心房颤动分析，表征和作图的方法和系统。 生成表示心脏物理结构的有限元模型（FEM）。 可以使用电生理学导管在心脏的各个位置感测电图数据，并将电描记图数据映射到FEM的元件。 然后，基于映射到有限元法的元素的电描绘图数据，同时计算所有元素的功能参数，测量AF心律失常的某些特征。 人工神经网络（ANN）可用于计算功能参数。

公开(公告)号：US08086303B2

公开(公告)日：2011-12-27

申请号：US11956795

申请日：2007-12-14

申请人： Hongxuan Zhang ,  Detlef W. Koertge

发明人： Hongxuan Zhang ,  Detlef W. Koertge

IPC分类号： A61B5/0428 ,  A61B5/0452

CPC分类号： A61B5/04012 ,  A61B5/0452 ,  A61B5/7275

摘要： The disclosed method analyzes cardiac electrophysiological signals, including ECG and internal cardiac electrograms, based on multi-level symbolic complexity calculation and multi-dimensional mapping. The results may be used to objectively identify cardiac disorders, differentiate cardiac arrhythmias, characterize pathological severities, and predict life-threatening events. Multi-level symbolization and calculation of the electrophysiological signal is used provide better reliability and analysis resolution for identifying and characterizing cardiac disorders. Adaptive analysis of the cardiac signal complexity enables calculation efficiency and reliability with high SNR, and with low calculation volume and power consumption. One dimension (time or frequency domain) and multi-dimension symbolic analysis is used to provide more information of cardiac pathology and high risk rhythm transition to doctors.

摘要翻译： 所公开的方法基于多级符号复杂度计算和多维映射分析心电生理信号，包括ECG和内心电图。 结果可用于客观地识别心脏疾病，区分心律失常，表征病理严重程度，并预测危及生命的事件。 使用多电平符号化和计算电生理信号提供更好的可靠性和分析解决方案，用于识别和表征心脏疾病。 心脏信号复杂度的自适应分析使得具有高SNR的计算效率和可靠性，并且具有较低的计算量和功耗。 使用一维（时间或频域）和多维符号分析来提供更多的心脏病理学信息和高风险节律过渡到医生。

公开(公告)号：US07715907B2

公开(公告)日：2010-05-11

申请号：US11832153

申请日：2007-08-01

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Harold Wade ,  Myrtis Randolph ,  Lori Palmquist

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Harold Wade ,  Myrtis Randolph ,  Lori Palmquist

IPC分类号： A61B5/0402

CPC分类号： A61B5/046 ,  A61B5/7264 ,  A61B5/7425 ,  A61B2576/023

摘要： A method and system for atrial fibrillation analysis, characterization, and mapping is disclosed. A finite element model (FEM) representing a physical structure of a heart is generated. Electrogram data can be sensed at various locations in the heart using an electrophysiology catheter, and the electrogram data is mapped to the elements of the FEM. Function parameters, which measure some characteristics of AF arrhythmia, are then simultaneously calculated for all of the elements of the FEM based on the electrogram data mapped to the elements of the FEM. An artificial neural network (ANN) can be used to calculate the function parameters.

摘要翻译： 公开了一种用于心房颤动分析，表征和作图的方法和系统。 生成表示心脏物理结构的有限元模型（FEM）。 可以使用电生理学导管在心脏的各个位置感测电图数据，并将电描记图数据映射到FEM的元件。 然后，基于映射到有限元法的元素的电描绘图数据，同时计算所有元素的功能参数，测量AF心律失常的某些特征。 人工神经网络（ANN）可用于计算功能参数。

公开(公告)号：US20110015532A1

公开(公告)日：2011-01-20

申请号：US12891831

申请日：2010-09-28

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

IPC分类号： A61B5/0402

CPC分类号： A61B5/0402 ,  A61B5/0428 ,  A61B5/7207

摘要： A system denoises and rejects artifacts from cardiac signals, by accepting a cardiac signal from a patient, processing the cardiac signal from the patient using a frequency band width controllable choke to separate the cardiac signal into predefined frequencies, filtering each of the predefined frequencies to remove dynamic common noise, joining each of the predefined frequencies into a cardiac signal without the dynamic common noise, and providing feedback control of the filtering of each of the predefined frequencies.

摘要翻译： 系统通过接受来自患者的心脏信号来去除和拒绝来自心脏信号的人造物，使用频带可控扼流圈处理来自患者的心脏信号，以将心脏信号分离成预定义的频率，过滤每个预定频率以去除 动态公共噪声，将每个预定义的频率连接到没有动态公共噪声的心脏信号中，以及提供对每个预定频率的滤波的反馈控制。

公开(公告)号：US20080281216A1

公开(公告)日：2008-11-13

申请号：US11956795

申请日：2007-12-14

申请人： Hongxuan Zhang ,  Detlef W. Koertge

发明人： Hongxuan Zhang ,  Detlef W. Koertge

IPC分类号： A61B5/0402 ,  A61B5/0432

CPC分类号： A61B5/04012 ,  A61B5/0452 ,  A61B5/7275

摘要： The disclosed method analyzes cardiac electrophysiological signals, including ECG and internal cardiac electrograms, based on multi-level symbolic complexity calculation and multi-dimensional mapping. The results may be used to objectively identify cardiac disorders, differentiate cardiac arrhythmias, characterize pathological severities, and predict life-threatening events. Multi-level symbolization and calculation of the electrophysiological signal is used provide better reliability and analysis resolution for identifying and characterizing cardiac disorders. Adaptive analysis of the cardiac signal complexity enables calculation efficiency and reliability with high SNR, and with low calculation volume and power consumption. One dimension (time or frequency domain) and multi-dimension symbolic analysis is used to provide more information of cardiac pathology and high risk rhythm transition to doctors.

摘要翻译： 所公开的方法基于多级符号复杂度计算和多维映射分析心电生理信号，包括ECG和内心电图。 结果可用于客观地识别心脏疾病，区分心律失常，表征病理严重程度，并预测危及生命的事件。 使用多电平符号化和计算电生理信号提供更好的可靠性和分析解决方案，用于识别和表征心脏疾病。 心脏信号复杂度的自适应分析使得具有高SNR的计算效率和可靠性，并且具有较低的计算量和功耗。 使用一维（时间或频域）和多维符号分析来提供更多的心脏病理学信息和高风险节律过渡到医生。

公开(公告)号：US20080269628A1

公开(公告)日：2008-10-30

申请号：US11831143

申请日：2007-07-31

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

IPC分类号： A61B5/0402

CPC分类号： A61B5/0428 ,  A61B5/0402 ,  A61B5/7207 ,  A61B5/7217

摘要： A method and apparatus for denoising and rejecting artifacts from cardiac signals, having the steps of accepting a cardiac signal from a patient, subjecting the cardiac signal from the patient to a frequency band width controllable choke to separate the cardiac signal into predefined frequencies, filtering each of the predefined frequencies to remove dynamic common noise, joining each of the predefined frequencies into a cardiac signal without the dynamic common noise, and providing a feedback control to the filtering of each of the predefined frequencies.

摘要翻译： 一种用于从心脏信号中去噪和排除伪影的方法和装置，具有接受来自患者的心脏信号的步骤，使来自患者的心脏信号经受频带可控扼流圈以将心脏信号分离成预定频率， 的预定频率以去除动态公共噪声，将每个预定义的频率连接到没有动态公共噪声的心脏信号中，并且提供对每个预定频率的滤波的反馈控制。

公开(公告)号：US20080191850A1

公开(公告)日：2008-08-14

申请号：US11832106

申请日：2007-08-01

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

IPC分类号： G05B11/01

CPC分类号： H04B5/0075 ,  H04L5/06 ,  H04L25/0268

摘要： An apparatus and method for signal transmission with isolation in medical devices. Data signals, such as patient measurement data and medical instrumentation control signals are converted to dynamic signals which are transmitted on power lines through an isolation module, such as a transformer. The dynamic signals are then converted to data signals having a voltage based on the frequency of the dynamic signals.

摘要翻译： 一种医疗设备隔离信号传输的装置和方法。 诸如患者测量数据和医疗仪器控制信号的数据信号被转换成通过诸如变压器的隔离模块在电力线路上传输的动态信号。 然后将动态信号转换成具有基于动态信号的频率的电压的数据信号。

公开(公告)号：US07942817B2

公开(公告)日：2011-05-17

申请号：US12330948

申请日：2008-12-09

申请人： Hongxuan Zhang ,  Detlef W. Koertge

发明人： Hongxuan Zhang ,  Detlef W. Koertge

IPC分类号： A61B5/00 ,  A61B5/04 ,  A61N1/37

CPC分类号： A61B5/0002 ,  A61B2560/0271 ,  Y10S128/903 ,  Y10S128/904

摘要： A medical signal interface device bidirectionally conveys signals between a patient and patient monitoring devices. The device comprises a bidirectional electrical signal interface that receives and buffers patient parameter monitoring signals received from a patient via patient attached leads and outputs treatment related signals used in applying invasive or non-invasive treatment to a patient. A bidirectional electrical signal processor operates in response to commands received from a control processor and is coupled to the electrical signal interface, for processing received patient parameter monitoring signals using filtering and amplification to provide processed patient monitoring signals for output to at least one patient monitoring device. The bidirectional electrical signal processor processes the treatment related signals for output by buffering the treatment related signals for output to a patient. A control processor provides data representing the commands in response to at least one of, (a) predetermined configuration data and (b) deriving data representing the commands from data entered by a user via a displayed user interface image.

摘要翻译： 医疗信号接口设备在患者和患者监视设备之间双向传送信号。 该装置包括双向电信号接口，其接收并缓冲患者通过患者附着的引线接收的患者参数监测信号，并输出用于向患者施加侵入性或非侵入性治疗的治疗相关信号。 双向电信号处理器响应于从控制处理器接收到的命令而操作并耦合到电信号接口，用于使用滤波和放大来处理接收到的患者参数监视信号，以提供处理的患者监视信号以输出至少一个患者监视装置 。 双向电信号处理器通过缓冲处理相关信号来处理与治疗相关的信号以输出以输出给患者。 控制处理器响应于（a）预定配置数据和（b）通过显示的用户界面图像从用户输入的数据导出表示命令的数据，提供表示命令的数据。

公开(公告)号：US07839011B2

公开(公告)日：2010-11-23

申请号：US11832106

申请日：2007-08-01

申请人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

发明人： Detlef W. Koertge ,  Hongxuan Zhang ,  Bryon Pelzek

IPC分类号： H02J3/00

CPC分类号： H04B5/0075 ,  H04L5/06 ,  H04L25/0268

摘要： An apparatus and method for signal transmission with isolation in medical devices. Data signals, such as patient measurement data and medical instrumentation control signals are converted to dynamic signals which are transmitted on power lines through an isolation module, such as a transformer. The dynamic signals are then converted to data signals having a voltage based on the frequency of the dynamic signals.

摘要翻译： 一种医疗设备隔离信号传输的装置和方法。 诸如患者测量数据和医疗仪器控制信号的数据信号被转换成通过诸如变压器的隔离模块在电力线路上传输的动态信号。 然后将动态信号转换成具有基于动态信号的频率的电压的数据信号。

公开(公告)号：US20090177046A1

公开(公告)日：2009-07-09

申请号：US12330948

申请日：2008-12-09

申请人： Hongxuan Zhang ,  Detlef W. Koertge

发明人： Hongxuan Zhang ,  Detlef W. Koertge

IPC分类号： A61B5/00

CPC分类号： A61B5/0002 ,  A61B2560/0271 ,  Y10S128/903 ,  Y10S128/904

摘要： A medical signal interface device bidirectionally conveys signals between a patient and patient monitoring devices. The device comprises a bidirectional electrical signal interface that receives and buffers patient parameter monitoring signals received from a patient via patient attached leads and outputs treatment related signals used in applying invasive or non-invasive treatment to a patient. A bidirectional electrical signal processor operates in response to commands received from a control processor and is coupled to the electrical signal interface, for processing received patient parameter monitoring signals using filtering and amplification to provide processed patient monitoring signals for output to at least one patient monitoring device. The bidirectional electrical signal processor processes the treatment related signals for output by buffering the treatment related signals for output to a patient. A control processor provides data representing the commands in response to at least one of, (a) predetermined configuration data and (b) deriving data representing the commands from data entered by a user via a displayed user interface image.

摘要翻译： 医疗信号接口设备在患者和患者监视设备之间双向传送信号。 该装置包括双向电信号接口，其接收并缓冲患者通过患者附着的引线接收的患者参数监测信号，并输出用于向患者施加侵入性或非侵入性治疗的治疗相关信号。 双向电信号处理器响应于从控制处理器接收到的命令而操作并耦合到电信号接口，用于使用滤波和放大来处理接收到的患者参数监视信号，以提供处理的患者监视信号以输出至少一个患者监视装置 。 双向电信号处理器通过缓冲处理相关信号来处理与治疗相关的信号以输出以输出给患者。 控制处理器响应于（a）预定配置数据和（b）通过显示的用户界面图像从用户输入的数据导出表示命令的数据，提供表示命令的数据。