公开(公告)号：US12102417B2

公开(公告)日：2024-10-01

申请号：US17673995

申请日：2022-02-17

Applicant: Acutus Medical, Inc.

Inventor： Christoph Scharf ,  Gunter Scharf ,  Randell L. Werneth

IPC: A61B5/00 ,  A61B5/0205 ,  A61B5/287 ,  A61B5/367 ,  A61B8/00 ,  A61B8/08 ,  A61B8/12 ,  A61B18/14 ,  A61B5/06

CPC classification number: A61B5/0205 ,  A61B5/0036 ,  A61B5/287 ,  A61B5/367 ,  A61B5/6858 ,  A61B8/0841 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/445 ,  A61B8/4483 ,  A61B8/5207 ,  A61B18/1492 ,  A61B5/065 ,  A61B5/6869 ,  A61B2562/0204 ,  A61B2562/0209 ,  A61B2576/023

Abstract: Disclosed are devices, systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various located within the associated chamber of the heart. To create a database of dipole densities, mapping information recorded by multiple electrodes located on one or more catheters and anatomical information is used. In addition, skin electrodes may be implemented. Additionally, one or more ultrasound elements are provided, such as on a clamp assembly or integral to a mapping electrode, to produce real time images of device components and surrounding structures.

公开(公告)号：US20240315770A1

公开(公告)日：2024-09-26

申请号：US18674533

申请日：2024-05-24

Applicant: Boston Scientific Scimed, Inc.

Inventor： Steven R. Mickelsen

IPC: A61B18/14 ,  A61B5/0538 ,  A61B17/00 ,  A61B18/00 ,  A61B18/12 ,  A61B18/18 ,  A61N1/04 ,  A61N1/32 ,  A61N7/02

CPC classification number: A61B18/1492 ,  A61B5/0538 ,  A61N1/327 ,  A61N7/022 ,  A61B2017/00026 ,  A61B2017/00154 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00654 ,  A61B2018/00827 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00994 ,  A61B2018/124 ,  A61B2018/1467 ,  A61B18/1815 ,  A61B2218/002 ,  A61B2576/023 ,  A61N1/0412

Abstract: Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

公开(公告)号：US20240307116A1

公开(公告)日：2024-09-19

申请号：US18674607

申请日：2024-05-24

Applicant: Boston Scientific Scimed, Inc.

Inventor： Steven R. Mickelsen

IPC: A61B18/14 ,  A61B5/0538 ,  A61B17/00 ,  A61B18/00 ,  A61B18/12 ,  A61B18/18 ,  A61N1/04 ,  A61N1/32 ,  A61N7/02

CPC classification number: A61B18/1492 ,  A61B5/0538 ,  A61N1/327 ,  A61N7/022 ,  A61B2017/00026 ,  A61B2017/00154 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00654 ,  A61B2018/00827 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00994 ,  A61B2018/124 ,  A61B2018/1467 ,  A61B18/1815 ,  A61B2218/002 ,  A61B2576/023 ,  A61N1/0412

Abstract: Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

公开(公告)号：US20240299089A1

公开(公告)日：2024-09-12

申请号：US18664163

申请日：2024-05-14

Applicant: Boston Scientific Scimed, Inc.

Inventor： Steven R. Mickelsen

IPC: A61B18/14 ,  A61B5/0538 ,  A61B17/00 ,  A61B18/00 ,  A61B18/12 ,  A61B18/18 ,  A61N1/04 ,  A61N1/32 ,  A61N7/02

CPC classification number: A61B18/1492 ,  A61B5/0538 ,  A61N1/327 ,  A61N7/022 ,  A61B2017/00026 ,  A61B2017/00154 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00351 ,  A61B2018/00404 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61B2018/00654 ,  A61B2018/00827 ,  A61B2018/00839 ,  A61B2018/00875 ,  A61B2018/00892 ,  A61B2018/00994 ,  A61B2018/124 ,  A61B2018/1467 ,  A61B18/1815 ,  A61B2218/002 ,  A61B2576/023 ,  A61N1/0412

Abstract: Catheter systems and methods for the selective and rapid application of DC voltage to drive irreversible electroporation are disclosed herein. In some embodiments, an apparatus includes a voltage pulse generator and an electrode controller. The voltage pulse generator is configured to produce a pulsed voltage waveform. The electrode controller is configured to be operably coupled to the voltage pulse generator and a medical device including a series of electrodes. The electrode controller includes a selection module and a pulse delivery module. The selection module is configured to select a subset of electrodes from the series of electrodes. The selection module is configured identify at least one electrode as an anode and at least one electrode as a cathode. The pulse delivery module is configured to deliver an output signal associated with the pulsed voltage waveform to the subset of electrodes.

公开(公告)号：US12064251B2

公开(公告)日：2024-08-20

申请号：US17013003

申请日：2020-09-04

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： Bin He ,  Zhaoye Zhou

IPC: A61B5/316 ,  A61B5/333 ,  A61B5/361 ,  A61B5/00 ,  A61B5/055 ,  A61B6/03 ,  A61B6/50

CPC classification number: A61B5/316 ,  A61B5/333 ,  A61B5/361 ,  A61B5/0037 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/7278 ,  A61B5/7289 ,  A61B6/032 ,  A61B6/507 ,  A61B2576/023

Abstract: A system and method for non-invasively generating a report of cardiac electrical activities of a subject includes determining, using cardiac electrical activation information, equivalent current densities (ECDs). The ECDs are assembled into time-course ECD information and a spectrum of the time-course ECD information is analyzed to determine peaks for spectral characteristics of atrial fibrillation (AF). The spectral characteristics of AF are correlated with potential electrical sources of the AF and a report is generated indicating the potential electrical sources of the AF spatially registered with the medical imaging data.

公开(公告)号：US12053258B2

公开(公告)日：2024-08-06

申请号：US16849045

申请日：2020-04-15

Applicant: Acutus Medical, Inc.

Inventor： Daniel J. Welsh ,  Marcus F. Julian ,  Graydon E. Beatty ,  Xinwei Shi ,  Derrick R. Chou ,  Randell L. Werneth ,  J. Christopher Flaherty ,  Mark MacGregor

IPC: A61B5/06 ,  A61B5/00 ,  A61B5/283 ,  A61B5/287 ,  A61B5/308 ,  A61B5/343 ,  A61B8/08 ,  A61B8/12 ,  A61N1/37 ,  A61B5/316 ,  A61B8/00 ,  A61B34/20

CPC classification number: A61B5/004 ,  A61B5/0035 ,  A61B5/0044 ,  A61B5/061 ,  A61B5/063 ,  A61B5/283 ,  A61B5/287 ,  A61B5/308 ,  A61B5/343 ,  A61B5/6852 ,  A61N1/3702 ,  A61B5/316 ,  A61B5/6853 ,  A61B5/6857 ,  A61B5/6858 ,  A61B5/6859 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/4416 ,  A61B34/20 ,  A61B2034/2051 ,  A61B2034/2063 ,  A61B2034/2065 ,  A61B2562/0204 ,  A61B2562/0209 ,  A61B2576/023

Abstract: Provided are a localization system and method useful in the acquisition and analysis of cardiac information. The localization system and method can be used with systems that perform cardiac mapping, diagnosis and treatment of cardiac abnormalities, as examples, and in the retrieval, processing, and interpretation of such types of information. The localization system and method use high impedance inputs, improved isolation, and relatively high drive currents for pairs of electrodes used to establish a multi-axis coordinate system. The axes can be rotated and scaled to improve localization.

公开(公告)号：US12016635B2

公开(公告)日：2024-06-25

申请号：US17330521

申请日：2021-05-26

Applicant: HeartFlow, Inc.

Inventor： Charles A. Taylor

IPC: G06T7/00 ,  A61B5/00 ,  A61B5/02 ,  A61B5/021 ,  A61B5/024 ,  A61B5/026 ,  A61B5/029 ,  A61B5/055 ,  A61B5/107 ,  A61B5/11 ,  A61B5/22 ,  A61B6/00 ,  A61B6/03 ,  A61B6/50 ,  A61B8/02 ,  A61B8/04 ,  A61B8/06 ,  A61B8/08 ,  A61B34/00 ,  A61B34/10 ,  A61M5/00 ,  G01R33/56 ,  G01R33/563 ,  G06F17/10 ,  G06F18/10 ,  G06F18/22 ,  G06F18/24 ,  G06F30/20 ,  G06F30/23 ,  G06F30/28 ,  G06G7/60 ,  G06T7/11 ,  G06T7/12 ,  G06T7/13 ,  G06T7/149 ,  G06T7/20 ,  G06T7/60 ,  G06T7/62 ,  G06T7/70 ,  G06T7/73 ,  G06T11/00 ,  G06T11/20 ,  G06T11/60 ,  G06T15/10 ,  G06T17/00 ,  G06T17/20 ,  G06V10/40 ,  G06V10/42 ,  G06V10/44 ,  G06V20/69 ,  G16B5/00 ,  G16B45/00 ,  G16H10/40 ,  G16H10/60 ,  G16H30/20 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50 ,  G16H50/70 ,  G16H70/00 ,  A61B90/00 ,  G06T7/10 ,  G06V10/46

CPC classification number: A61B34/10 ,  A61B5/0035 ,  A61B5/004 ,  A61B5/0044 ,  A61B5/02 ,  A61B5/02007 ,  A61B5/02028 ,  A61B5/021 ,  A61B5/024 ,  A61B5/026 ,  A61B5/0263 ,  A61B5/029 ,  A61B5/055 ,  A61B5/1075 ,  A61B5/1118 ,  A61B5/22 ,  A61B5/4848 ,  A61B5/6852 ,  A61B5/7246 ,  A61B5/7275 ,  A61B5/7278 ,  A61B5/745 ,  A61B6/03 ,  A61B6/032 ,  A61B6/481 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5205 ,  A61B6/5217 ,  A61B6/5229 ,  A61B8/02 ,  A61B8/04 ,  A61B8/06 ,  A61B8/065 ,  A61B8/481 ,  A61B8/5223 ,  A61B8/5261 ,  A61B34/25 ,  A61M5/007 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56366 ,  G06F17/10 ,  G06F18/10 ,  G06F18/22 ,  G06F18/24 ,  G06F30/20 ,  G06F30/23 ,  G06F30/28 ,  G06G7/60 ,  G06T7/0012 ,  G06T7/0014 ,  G06T7/11 ,  G06T7/12 ,  G06T7/13 ,  G06T7/149 ,  G06T7/20 ,  G06T7/60 ,  G06T7/62 ,  G06T7/70 ,  G06T7/73 ,  G06T7/74 ,  G06T11/00 ,  G06T11/001 ,  G06T11/008 ,  G06T11/20 ,  G06T11/60 ,  G06T15/10 ,  G06T17/00 ,  G06T17/005 ,  G06T17/20 ,  G06V10/40 ,  G06V10/42 ,  G06V10/44 ,  G06V20/698 ,  G16B5/00 ,  G16B45/00 ,  G16H10/40 ,  G16H10/60 ,  G16H30/20 ,  G16H30/40 ,  G16H50/30 ,  G16H50/50 ,  G16H50/70 ,  G16H70/00 ,  A61B5/6868 ,  A61B2034/104 ,  A61B2034/105 ,  A61B2034/107 ,  A61B2034/108 ,  A61B2090/374 ,  A61B2090/3762 ,  A61B2090/3764 ,  A61B2576/00 ,  A61B2576/023 ,  G06T7/10 ,  G06T2200/04 ,  G06T2207/10012 ,  G06T2207/10072 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10104 ,  G06T2207/10108 ,  G06T2207/20036 ,  G06T2207/20124 ,  G06T2207/30016 ,  G06T2207/30048 ,  G06T2207/30104 ,  G06T2210/41 ,  G06T2211/404 ,  G06V10/467 ,  Y02A90/10 ,  G06T7/0012 ,  G06T2207/30048

Abstract: Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

公开(公告)号：US12004882B2

公开(公告)日：2024-06-11

申请号：US15522098

申请日：2015-10-27

Applicant: The Trustees of The University of Pennsylvania

Inventor： Walter R. T. Witschey ,  Francisco Contijoch ,  Mark A. Elliott ,  Eugene E. Gualtieri

IPC: A61B5/00 ,  A61B5/055 ,  A61B5/33 ,  G01R33/48 ,  G01R33/563 ,  G01R33/567

CPC classification number: A61B5/7289 ,  A61B5/0044 ,  A61B5/055 ,  A61B5/33 ,  G01R33/5673 ,  A61B2576/023 ,  G01R33/4824 ,  G01R33/56325

Abstract: An adaptive real-time radial k-space sampling trajectory (ARKS) can respond to a physiologic feedback signal to reduce motion effects and ensure sampling uniformity. In this adaptive k-space sampling strategy, the most recent signals from an ECG waveform can be continuously matched to the previous signal history, new radial k-space locations were determined, and these MR signals combined using multi-shot or single-shot radial acquisition schemes. The disclosed methods allow for improved MRI imaging.

公开(公告)号：US11990225B2

公开(公告)日：2024-05-21

申请号：US17256024

申请日：2019-07-01

Applicant: Navix International Limited

Inventor： Haim Rodriguez

IPC: G16H30/40 ,  A61B5/06 ,  G06T17/20

CPC classification number: G16H30/40 ,  A61B5/065 ,  G06T17/20 ,  A61B2576/023 ,  G06T2210/41

Abstract: There is provided a computer implemented method of reconstructing an image of a body cavity shape of a subject based on a plurality of location indications, indicating locations of at least one sensor disposed on an intrabody probe within the body cavity, the method comprising: receiving data indicative of the plurality of location indications, identifying based on the data at least a first group and a second group of location indications, and reconstructing the body cavity from the data, using a first reconstruction method for the first group of location indications, and a second reconstruction method for the second group of location indications.

公开(公告)号：US11969279B2

公开(公告)日：2024-04-30

申请号：US15823031

申请日：2017-11-27

Applicant: Medtronic Navigation, Inc.

Inventor： Patrick A. Helm ,  Shuanghe Shi

IPC: A61B6/00 ,  A61B6/02 ,  A61B6/46 ,  A61B6/50 ,  A61B34/20 ,  A61M5/00 ,  G06T11/00 ,  A61B6/40

CPC classification number: A61B6/481 ,  A61B6/02 ,  A61B6/4405 ,  A61B6/4476 ,  A61B6/469 ,  A61B6/482 ,  A61B6/486 ,  A61B6/503 ,  A61B6/504 ,  A61B6/507 ,  A61B6/5288 ,  A61B6/545 ,  A61M5/007 ,  G06T11/005 ,  A61B6/4085 ,  A61B34/20 ,  A61B2576/023 ,  G01N2223/419 ,  G06T2207/10081 ,  G06T2207/30048 ,  G06T2211/404 ,  G06T2211/412

Abstract: A method and system is disclosed for acquiring image data of a subject. The image data can be collected with an imaging system having a detector able to move relative to the subject. A contrast agent can be injected into the subject and image data can be acquired with the contrast agent in various phases of the subject. A volumetric model of multiple phases can be reconstructed selected reconstruction techniques.