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    SAFETY CONSTRAINTS FOR A CONTROL ALGORITHM BASED DRUG DELIVERY SYSTEM
    11.
    发明申请
    SAFETY CONSTRAINTS FOR A CONTROL ALGORITHM BASED DRUG DELIVERY SYSTEM 审中-公开

    公开(公告)号：US20190336684A1

    公开(公告)日：2019-11-07

    申请号：US16404456

    申请日：2019-05-06

    Applicant: Insulet Corporation

    Inventor： Jason O'CONNOR ,  Joon Bok LEE ,  Trang LY ,  Yibin ZHENG ,  Thomas Arnold PEYSER ,  Jennifer Lena SCHNEIDER

    IPC: A61M5/172 ,  A61M5/142 ,  A61M5/145 ,  A61B5/145

    Abstract: Disclosed are a system, methods and computer-readable medium products that provide safety constraints for an insulin-delivery management program. Various examples provide safety constraints for a control algorithm-based drug delivery system that provides automatic delivery of a drug based on sensor input. Glucose measurement values may be received at regular time intervals from a sensor. A processor may predict future glucose values based on prior glucose measurement values. The safety constraints assist in safe operation of the drug delivery system during various operational scenarios. In some examples, predicted future glucose values may be used to implement safety constraints that mitigate under-delivery or over-delivery of the drug while not overly burdening the user of the drug delivery system and without sacrificing performance of the drug delivery system. Other safety constraints are also disclosed.

    FLUID FLOW REGULATION ARRANGEMENTS FOR DRUG DELIVERY DEVICES
    12.
    发明申请
    FLUID FLOW REGULATION ARRANGEMENTS FOR DRUG DELIVERY DEVICES 审中-公开

    公开(公告)号：US20190038835A1

    公开(公告)日：2019-02-07

    申请号：US16049388

    申请日：2018-07-30

    Applicant: Insulet Corporation

    Inventor： David NAZZARO ,  Ian MCLAUGHLIN ,  Daniel ALLIS ,  Jason O'CONNOR

    IPC: A61M5/168 ,  A61M5/28 ,  A61M5/32 ,  A61M5/315

    Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.

    PROGRAMMATIC MEDICAMENT TITRATION WITH A MEDICAMENT DELIVERY DEVICE
    14.
    发明公开
    PROGRAMMATIC MEDICAMENT TITRATION WITH A MEDICAMENT DELIVERY DEVICE 审中-公开

    公开(公告)号：US20240148971A1

    公开(公告)日：2024-05-09

    申请号：US18386647

    申请日：2023-11-03

    Applicant: INSULET CORPORATION

    Inventor： Matthew ALLES ,  Yibin ZHENG ,  Joon Bok LEE ,  James CAUSEY ,  Jason O'CONNOR

    IPC: A61M5/172 ,  A61M5/142

    CPC classification number: A61M5/1723 ,  A61M5/14248 ,  A61M2202/0486

    Abstract: Exemplary embodiments may provide an on-body medicament delivery system that provides basal delivery of a medicament to a type 2 diabetes patient and that automatically performs medicament titration for the patient. The medicament delivery system performs medicament titration based on glucose level readings for the patient. These glucose levels may be provided wirelessly from a glucose sensor, such as a continuous glucose monitor, or may be entered manually by the patient into a management device, such as a smartphone running an application that provides a user interface for the patient to enter the glucose level readings. The medicament delivery system adjusts the basal medicament delivery rate/dose based on the glucose level readings for the patient. The adjustments may be performed by a programmatic mechanism, such as by computer programming instructions executing on a processor.

    TECHNIQUES ENABLING ADAPTATION OF PARAMETERS IN AID SYSTEMS BY USER INPUT
    16.
    发明公开
    TECHNIQUES ENABLING ADAPTATION OF PARAMETERS IN AID SYSTEMS BY USER INPUT 审中-公开

    公开(公告)号：US20230355874A1

    公开(公告)日：2023-11-09

    申请号：US18353523

    申请日：2023-07-17

    Applicant: INSULET CORPORATION

    Inventor： Joon Bok LEE ,  Bonnie DUMAIS ,  Jason O'CONNOR ,  Yibin ZHENG

    IPC: A61M5/172 ,  A61M5/142

    CPC classification number: A61M5/1723 ,  A61M5/14244 ,  A61M2230/201

    Abstract: Disclosed are techniques and devices that are operable to receive one or a number of generalized parameters of an automated insulin delivery algorithm. An input of at least one generalized parameter corresponding to a user may be used to set one or more of the number of specific parameters of the automated insulin delivery algorithm based on the inputted at least one generalized parameter. Physiological condition data related to the user may be collected. The automated insulin delivery algorithm may determine a dosage of insulin to be delivered based on the collected physiological condition. Signals may be output to cause a liquid drug to be delivered to the user based on an output of the automated insulin delivery algorithm related to the determined dosage of insulin.

    TECHNIQUES FOR DETERMINING MEDICATION CORRECTION FACTORS IN AUTOMATIC MEDICATION DELIVERY SYSTEMS
    18.
    发明公开
    TECHNIQUES FOR DETERMINING MEDICATION CORRECTION FACTORS IN AUTOMATIC MEDICATION DELIVERY SYSTEMS 审中-公开

    公开(公告)号：US20230248909A1

    公开(公告)日：2023-08-10

    申请号：US18164669

    申请日：2023-02-06

    Applicant: INSULET CORPORATION

    Inventor： Joon Bok LEE ,  James GRAHAM ,  Jason O'CONNOR ,  Yibin ZHENG

    IPC: A61M5/172 ,  G16H20/17

    CPC classification number: A61M5/1723 ,  G16H20/17 ,  A61M2202/0486 ,  A61M2205/52

    Abstract: Disclosed are processes and techniques for a correction factor determination process for determining a correction factor for delivering a drug to a patient via a drug delivery device. For example, for an insulin delivery device, the disclosed techniques enable adjustment of the patient’s correction factor in real time based on the deviation of the patient’s glucose concentrations against clinically recommended targets. For example, a method for determining a correction factor may include determining an insulin action (Iaction) for a patient over a duration, the insulin action representing a total insulin metabolized, determining glucose information for the patient over the duration, the glucose information representing glucose activity, and determining an estimated correction factor (CFest) based on (glucose information) / (insulin action) for the duration. Other embodiments are described.

    USER INTERFACE DISPLAYS FOR ASSISTING IN MEDICAMENT BOLUS CALCULATION
    19.
    发明公开
    USER INTERFACE DISPLAYS FOR ASSISTING IN MEDICAMENT BOLUS CALCULATION 审中-公开

    公开(公告)号：US20230233762A1

    公开(公告)日：2023-07-27

    申请号：US18156497

    申请日：2023-01-19

    Applicant: INSULET CORPORATION

    Inventor： Joon Bok LEE ,  Yibin ZHENG ,  Jason O'CONNOR ,  Kerrie GALLAGHER ,  Lindsay PHILBRICK ,  Alex NGUYEN ,  Joshua WILLIAMS

    IPC: A61M5/172 ,  A61B5/145

    CPC classification number: A61M5/172 ,  A61B5/14532 ,  A61M2230/201

    Abstract: Exemplary embodiments may provide a user interface and logic for assisting a user in calculating a proper medicament bolus dosage. The user interface may be simple and easy to understand. The user interface may clearly specify needed inputs, such as a carbohydrates amount for a meal that is about to be ingested and the current glucose level reading for the user. Entered inputs may be displayed on the user interface. The user interface may depict key calculated values resulting from calculations that involve the inputs, including the total bolus dosage calculation. The user interface also may depict the values that contribute to the total bolus dosage calculation. Some of the input values, such as carbohydrates amount, may be prepopulated by the management device or medicament delivery device. The user interface may permit overriding of prepopulated input values.

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