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公开(公告)号：US08221748B2
公开(公告)日：2012-07-17
申请号：US12578332
申请日：2009-10-13
IPC分类号： A61K39/395 , A61K38/20 , C07K14/545 , C07K14/715
CPC分类号： A61K38/2006 , A61K38/1709 , C07K14/545 , C07K16/245 , G01N33/6869 , Y10S514/825
摘要： The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.
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公开(公告)号：US08148346B2
公开(公告)日：2012-04-03
申请号：US12568933
申请日：2009-09-29
CPC分类号： A61K38/2006 , A61K38/1709 , C07K14/545 , C07K16/245 , G01N33/6869 , Y10S514/825
摘要： The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.
摘要翻译： 本发明包括用于治疗患有自身炎症的患者的关节炎关节的组合物和方法，例如全身性发作的幼年特发性关节炎，通过在炎症部位施用治疗有效量的至少一种降低或阻断白介素 - 1＆bgr
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公开(公告)号：US20100068201A1
公开(公告)日：2010-03-18
申请号：US12578332
申请日：2009-10-13
IPC分类号： A61K39/395 , A61P19/02 , A61K31/485
CPC分类号： A61K38/2006 , A61K38/1709 , C07K14/545 , C07K16/245 , G01N33/6869 , Y10S514/825
摘要： The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.
摘要翻译： 本发明包括用于治疗患有自身炎症的患者的关节炎关节的组合物和方法，例如全身性发作的幼年特发性关节炎，通过在炎症部位施用治疗有效量的至少一种降低或阻断白介素 - 1＆bgr
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公开(公告)号：US07615212B2
公开(公告)日：2009-11-10
申请号：US11067335
申请日：2005-02-25
IPC分类号： A61K39/395 , A61K38/20
CPC分类号： A61K38/2006 , A61K38/1709 , C07K14/545 , C07K16/245 , G01N33/6869 , Y10S514/825
摘要： The present invention includes compositions and methods for treating arthritic joints found in patients with autoinflammation, e.g., systemic onset juvenile idiopathic arthritis, by administering at the site of inflammation a therapeutically effective amount of at least one agent that reduces or blocks the bioavailability of interleukin-1β.
摘要翻译： 本发明包括用于治疗患有自身炎症的患者的关节炎关节的组合物和方法，例如全身性发作的幼年特发性关节炎，通过在炎症部位施用治疗有效量的至少一种降低或阻断白介素 - 1beta。
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