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公开(公告)号：US11009509B2
公开(公告)日：2021-05-18
申请号：US15738013
申请日：2016-06-23
IPC分类号： C07K16/28 , G01N33/53 , G01N33/574 , A61K39/00
摘要： The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of detecting VISTA.
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公开(公告)号：US10899836B2
公开(公告)日：2021-01-26
申请号：US15430264
申请日：2017-02-10
IPC分类号： G01N33/53 , C07K16/28 , A61K39/395 , A61K45/06 , C07K16/30 , G01N33/574 , G01N33/68 , A61K39/00
摘要： The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Methods of identifying anti-VISTA antibodies capable of eliciting certain biological responses are also included.
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公开(公告)号：US20180306799A1
公开(公告)日：2018-10-25
申请号：US15738013
申请日：2016-06-23
IPC分类号： G01N33/574 , C07K16/28
CPC分类号： G01N33/57492 , A61K2039/505 , C07K16/2827 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/732 , C07K2317/74 , C07K2317/76 , C07K2317/92 , G01N2333/70532
摘要： The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of detecting VISTA.
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公开(公告)号：US20170320950A1
公开(公告)日：2017-11-09
申请号：US15481410
申请日：2017-04-06
CPC分类号： C07K16/2827 , A61K2039/507 , C07K16/2803 , C07K16/2818 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Compositions and methods of using anti-VISTA antibodies in combination with one or more antibodies that bind to immune checkpoint proteins are also provided.
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