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公开(公告)号:US20210347896A1
公开(公告)日:2021-11-11
申请号:US17325792
申请日:2021-05-20
IPC分类号: C07K16/28
摘要: The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Compositions and methods of using anti-VISTA antibodies in combination with one or more antibodies that bind to immune checkpoint proteins are also provided.
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公开(公告)号:US10273301B2
公开(公告)日:2019-04-30
申请号:US15107784
申请日:2014-12-22
发明人: Linda Snyder , Gordon Powers
IPC分类号: C07K16/28 , A61K39/395 , G01N33/574 , A61K45/06 , A61K39/00
摘要: The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of making and using same. Methods of use include methods of treatment of cancer, including leukemias, lymphomas, solid tumors and melanomas.
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公开(公告)号:US20170233479A1
公开(公告)日:2017-08-17
申请号:US15430264
申请日:2017-02-10
IPC分类号: C07K16/28 , G01N33/574 , G01N33/68
CPC分类号: C07K16/2827 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/3015 , C07K16/3023 , C07K16/3038 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/57423 , G01N33/6854 , G01N2800/7028
摘要: The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Methods of identifying anti-VISTA antibodies capable of eliciting certain biological responses are also included.
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公开(公告)号:US11014987B2
公开(公告)日:2021-05-25
申请号:US15481410
申请日:2017-04-06
IPC分类号: C07K16/28 , A61K39/395 , A61K39/00
摘要: The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Compositions and methods of using anti-VISTA antibodies in combination with one or more antibodies that bind to immune checkpoint proteins are also provided.
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公开(公告)号:US20170051061A1
公开(公告)日:2017-02-23
申请号:US15107784
申请日:2014-12-22
发明人: Linda Snyder , Gordon Powers
IPC分类号: C07K16/28 , A61K39/395 , A61K45/06 , C07K16/30
CPC分类号: C07K16/2827 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K16/3015 , C07K16/3023 , C07K16/3038 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/732 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N33/57426 , G01N33/5743 , G01N33/57492
摘要: The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of making and using same. Methods of use include methods of treatment of cancer, including leukemias, lymphomas, solid tumors and melanomas.
摘要翻译: 本发明涉及结合V细胞Ig抑制剂T细胞活化(VISTA)的新抗体和片段,以及制备和使用它们的方法。 使用方法包括治疗癌症的方法,包括白血病,淋巴瘤,实体瘤和黑素瘤。
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公开(公告)号:US11987630B2
公开(公告)日:2024-05-21
申请号:US17104287
申请日:2020-11-25
IPC分类号: G01N33/68 , A61K39/395 , A61K45/06 , C07K16/28 , C07K16/30 , G01N33/574 , A61K39/00
CPC分类号: C07K16/2827 , A61K39/39558 , A61K45/06 , C07K16/3015 , C07K16/3023 , C07K16/3038 , G01N33/57423 , G01N33/6854 , A61K2039/505 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/74 , C07K2317/75 , C07K2317/76 , C07K2317/92 , G01N2800/7028
摘要: The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Methods of identifying anti-VISTA antibodies capable of eliciting certain biological responses are also included.
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公开(公告)号:US20220144954A1
公开(公告)日:2022-05-12
申请号:US17529711
申请日:2021-11-18
发明人: Linda Snyder , Gordon Powers
摘要: The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of making and using same. Methods of use include methods of treatment of cancer, including leukemias, lymphomas, solid tumors and melanomas.
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公开(公告)号:US20210171640A1
公开(公告)日:2021-06-10
申请号:US17104287
申请日:2020-11-25
IPC分类号: C07K16/28 , A61K39/395 , A61K45/06 , C07K16/30 , G01N33/574 , G01N33/68
摘要: The present invention relates to antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of eliciting certain biological responses using the antibodies. Methods of identifying anti-VISTA antibodies capable of eliciting certain biological responses are also included.
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公开(公告)号:US11242392B2
公开(公告)日:2022-02-08
申请号:US16395585
申请日:2019-04-26
发明人: Linda Snyder , Gordon Powers
IPC分类号: C07K16/28 , A61K39/395 , G01N33/574 , A61K45/06 , C07K16/30 , A61K39/00
摘要: The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of making and using same. Methods of use include methods of treatment of cancer, including leukemias, lymphomas, solid tumors and melanomas.
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公开(公告)号:US20210318322A1
公开(公告)日:2021-10-14
申请号:US17205193
申请日:2021-03-18
IPC分类号: G01N33/574 , C07K16/28
摘要: The present invention relates to novel antibodies and fragments that bind to a V-domain Ig Suppressor of T cell Activation (VISTA), and methods of detecting VISTA.
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