公开(公告)号：US5350763A

公开(公告)日：1994-09-27

申请号：US75253

申请日：1993-06-11

申请人： Scott D. Feighner ,  Gino M. Salituro ,  Jack L. Smith ,  Nancy N. Tsou

发明人： Scott D. Feighner ,  Gino M. Salituro ,  Jack L. Smith ,  Nancy N. Tsou

IPC分类号： A61K31/335 ,  A61K31/365 ,  C07D321/10

CPC分类号： A61K31/335 ,  A61K31/365 ,  C07D321/10

摘要： Unguinol is a well-known metabolite of the fungi Aspergillus unguis and Aspergillus nidulans. Unguinol has been found to be an active growth permittant and promotant in animals, in particular, monogastric animals such as chickens. In addition, the fermentation broth also produced the additional known unguinol derivatives of folipastatin and 2-chloro unguinol as well as the novel 4-methyl derivative. All of these compounds are active animal growth permittants. Compositions containing such unguinol derivatives for use as growth permittants and promotants are also disclosed.

摘要翻译： Unguinol是真菌Aspergillus unguis和构巢曲霉的着名代谢物。 已经发现乌尼诺醇是动物中的活性生长促进剂和促进剂，特别是单胃动物例如鸡。 此外，发酵液还产生了另外已知的叶酸酯和2-氯壬基酚的非诺醇衍生物以及新的4-甲基衍生物。 所有这些化合物都是活性动物生长容许剂。 还公开了含有用作生长剂和促进剂的非诺醇衍生物的组合物。