公开(公告)号：US5869683A

公开(公告)日：1999-02-09

申请号：US962648

申请日：1997-11-03

申请人： Hisayoshi Jonishi ,  Tokiya Kimura ,  Fumio Kanamori ,  Shigehisa Kanbayashi ,  Tooru Wakabayashi ,  Fumihiro Fukui ,  Akimasa Takenaka ,  Noriyuki Horiuchi

发明人： Hisayoshi Jonishi ,  Tokiya Kimura ,  Fumio Kanamori ,  Shigehisa Kanbayashi ,  Tooru Wakabayashi ,  Fumihiro Fukui ,  Akimasa Takenaka ,  Noriyuki Horiuchi

IPC分类号： C07C45/63 ,  C07C251/48 ,  C07D233/54 ,  C07D233/90

CPC分类号： C07D233/54 ,  C07C251/48 ,  C07C45/63 ,  C07D233/90

摘要： A process for producing 1-substituted-2-cyanoimidazole compounds is described, which comprises (1) undergoing a reaction of a compound represented by formula (IV), hydroxylamine or a mineral acid salt thereof, and glyoxal or glyoxime to produce a compound represented by formula (III), (2) undergoing a reaction of the compound represented by formula (III) with thionyl chloride or thionyl bromide in the presence of N,N-dialkylamide to produce a reaction mixture, and then reacting the produced reaction mixture with sulfur chloride to produce a 2-cyanoimidazole compound represented by formula (II), and (3) undergoing a sulfamoylation reaction and an isomerization reaction of the 2-cyanoimidazole compound represented by formula (II) and a compound represented by formula (V) in the presence of at least one base selected from carbonates of alkali metals and bicarbonates of alkali metals and a polar solvent to produce a 1-substituted-2-cyanoimidazole compound represented by formula (I-b). The formulae and substituents formulae are specifically defined in the specification. ##STR1##

摘要翻译： 描述了一种制备1-取代-2-氰基咪唑化合物的方法，其包括（1）进行由式（Ⅳ）表示的化合物，羟胺或其无机酸盐与乙二醛或乙肟的反应，以制备代表 通过式（III），（2）在N，N-二烷基酰胺存在下，将由式（III）表示的化合物与亚硫酰氯或亚硫酰溴反应生成反应混合物，然后使所产生的反应混合物与 制备由式（II）表示的2-氰基咪唑化合物，和（3）进行氨基甲酰化反应和由式（II）表示的2-氰基咪唑化合物和式（V）表示的化合物的异构化反应在 存在选自碱金属和碱金属的碳酸氢盐的碳酸盐和极性溶剂的至少一种碱，以制备由式（Ib）表示的1-取代-2-氰基咪唑化合物。 式和取代基式在本说明书中具体定义。 （四）

公开(公告)号：US5583231A

公开(公告)日：1996-12-10

申请号：US412017

申请日：1995-03-28

申请人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

发明人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

IPC分类号： A01N47/36 ,  C07D213/75 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00 ,  C07D213/70 ,  C07D213/71

CPC分类号： C07D213/75 ,  A01N47/36 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00

摘要： A substituted pyridinesulfonamide compound or its salt represented by the following general formula (I): ##STR1## wherein A is CH or N; when A is CH, R.sub.1 and R.sub.2 may be either each independently a member selected from the group consisting of unsubstituted or substituted alkyl groups, unsubstituted or substituted alkenyl groups, unsubstituted or substituted cycloalkyl groups, and unsubstituted or substituted phenyl groups; when A is N, R.sub.1 is an unsubstituted or substituted alkyl group, R.sub.2 is an unsubstituted or substituted alkyl group, or an unsubstituted or substituted alkoxy group; and X and Y are each independently a member selected from the group consisting of alkyl groups and alkoxy groups, is disclosed. This compound is useful as the effective ingredient of a herbicide showing a wide weed-control spectrum even if used in a small amount.

摘要翻译： 由以下通式（I）表示的取代的吡啶磺酰胺化合物或其盐：其中A是CH或N; 当A是CH时，R 1和R 2可以各自独立地选自未取代或取代的烷基，未取代或取代的烯基，未取代或取代的环烷基和未取代或取代的苯基; 当A为N时，R 1为未取代或取代的烷基，R 2为未取代或取代的烷基，或未取代或取代的烷氧基; 并且X和Y各自独立地是选自烷基和烷氧基的成员。 即使少量使用，该化合物也可用作除草剂的有效成分，显示宽的杂草控制谱。

公开(公告)号：US5457084A

公开(公告)日：1995-10-10

申请号：US240896

申请日：1994-05-11

申请人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

发明人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

IPC分类号： A01N47/36 ,  C07D213/75 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00 ,  C07D239/42 ,  A01N43/54

CPC分类号： C07D213/75 ,  A01N47/36 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00

摘要： A substituted pyridinesulfonamide compound or its salt represented by the following formula (I): ##STR1## wherein A is CH; R.sub.1 and R.sub. 2 are each independently a member selected from the group consisting of unsubstituted or substituted alkyl groups, unsubstituted or substituted alkenyl groups, unsubstituted or substituted cycloalkyl groups, and unsubstituted or substituted phenyl groups; and X and Y are each independently a member selected from the group consisting of alkyl groups and alkoxy groups. This compound is an effective ingredient in a herbicide showing a wide weed-control spectrum even when used in a small amount.

摘要翻译： 由下式（I）表示的取代的吡啶磺酰胺化合物或其盐：其中A是CH; R1和R2各自独立地是选自未取代或取代的烷基，未取代或取代的烯基，未取代或取代的环烷基和未取代或取代的苯基的成员; X和Y各自独立地为选自烷基和烷氧基的成员。 即使在少量使用的情况下，该化合物也是除草剂中的有效成分，显示出宽的杂草控制谱。

公开(公告)号：US06806367B2

公开(公告)日：2004-10-19

申请号：US09983835

申请日：2001-10-26

申请人： Fumio Kanamori ,  Masamitsu Tsukamoto

发明人： Fumio Kanamori ,  Masamitsu Tsukamoto

IPC分类号： C07D4302

CPC分类号： C07D239/54 ,  C07D405/12

摘要： This invention relates to a method for producing compounds of the formula (I) or their salts: wherein each of R1 and R2 is hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, OR3, SR3, COR3, COOR3 or cyano; R1 and R2 may combine together with the adjacent carbon atom of ═CR1R2 to form an unsubstituted or substituted cyclic ring; each of R4 and R5 is hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted alkenyl, unsubstituted or substituted alkynyl, unsubstituted or substituted aryl, unsubstituted or substituted heteroaryl, NR6R7, OR8 or SR9; R4 and R5 may combine together with the adjacent skeleton of C/N bond to form a heterocyclic ring; which comprises rearranging compounds of the formula (II) or their salts: wherein R1, R2, R4 and R5 are as defined above.

摘要翻译： 本发明涉及制备式（I）化合物或其盐的方法：其中R1和R2各自为氢，未取代或取代的烷基，未取代或取代的烯基，未取代或取代的炔基，未取代或取代的芳基，未取代或未取代的 取代的杂芳基，OR 3，SR 3，COR 3，COOR 3或氰基; R 1和R 2可与CR 1 R 2的相邻碳原子一起形成未取代或取代的环; R 4和R 5各自为氢，未取代或取代的烷基， 或取代的烯基，未取代或取代的炔基，未取代或取代的芳基，未取代或取代的杂芳基，NR6R7，OR8或SR9; R4和R5可以与C / N键的相邻骨架结合形成杂环;其包括重排化合物 的式（II）或其盐：其中R 1，R 2，R 4和R 5如上所定义。

公开(公告)号：US5348933A

公开(公告)日：1994-09-20

申请号：US28165

申请日：1993-03-09

申请人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

发明人： Nobuyuki Sakashita ,  Toshio Nakajima ,  Shigeo Murai ,  Kazuyuki Maeda ,  Yuji Nakamura ,  Tsunezo Yoshida ,  Shooichi Honzawa ,  Fumio Kanamori

IPC分类号： A01N47/36 ,  C07D213/75 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00 ,  A01N43/66

CPC分类号： C07D213/75 ,  A01N47/36 ,  C07D213/76 ,  C07D401/12 ,  C07D521/00

摘要： A substituted pyridinesulfonamide compound or its salt represented by the following general formula (I): ##STR1## wherein A is CH or N; when A is CH, R.sub.1 and R.sub.2 may be either each independently a member selected from the group consisting of unsubstituted or substituted alkyl groups, unsubstituted or substituted alkenyl groups, unsubstituted or substituted cycloalkyl groups, and unsubstituted or substituted phenyl groups; when A is N, R.sub.1 is an unsubstituted or substituted alkyl group, R.sub.2 is an unsubstituted or substituted alkyl group, or an unsubstituted or substituted alkoxy group; and X and Y are each independently a member selected from the group consisting of alkyl groups and alkoxy groups, is disclosed. This compound is useful as the effective ingredient of a herbicide showing a wide weed-control spectrum even if used in a small amount.

摘要翻译： 由以下通式（I）表示的取代的吡啶磺酰胺化合物或其盐：其中A是CH或N; 当A是CH时，R 1和R 2可以各自独立地选自未取代或取代的烷基，未取代或取代的烯基，未取代或取代的环烷基和未取代或取代的苯基; 当A为N时，R 1为未取代或取代的烷基，R 2为未取代或取代的烷基，或未取代或取代的烷氧基; 并且X和Y各自独立地是选自烷基和烷氧基的成员。 即使少量使用，该化合物也可用作除草剂的有效成分，显示宽的杂草控制谱。

公开(公告)号：US08039633B2

公开(公告)日：2011-10-18

申请号：US11911725

申请日：2006-04-20

申请人： Shigeyuki Nishimura ,  Fumio Kanamori ,  Masashi Hisamoto

发明人： Shigeyuki Nishimura ,  Fumio Kanamori ,  Masashi Hisamoto

IPC分类号： C07D211/78 ,  C07D211/72

CPC分类号： C07D213/80 ,  C07D213/803

摘要： To provide a method for producing a specific nicotinic acid derivative or a salt thereof. A method for producing a nicotinic acid derivative represented by the formula (I): wherein each of X1 and X2 which are independent of each other, is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, a haloalkyl group or a haloalkoxy group; R is an alkyl group; and Hal is a chlorine atom or a bromine atom; or a salt thereof, is provided which comprises reacting a compound represented by the formula (II): is wherein X1, X2 and R are as defined above, or a salt thereof, with a halogenating agent.

摘要翻译： 提供生产特定烟酸衍生物或其盐的方法。 一种制备由式（I）表示的烟酸衍生物的方法：其中X1和X2彼此独立地为氢原子，卤素原子，烷基，烷氧基，卤代烷基或 卤代烷氧基; R是烷基; Hal是氯原子或溴原子; 或其盐，其包括使式（II）表示的化合物：其中X 1，X 2和R如上定义，或其盐与卤化剂反应。

公开(公告)号：US20090054656A1

公开(公告)日：2009-02-26

申请号：US11911725

申请日：2006-04-20

申请人： Shigeyuki Nishimura ,  Fumio Kanamori ,  Masashi Hisamoto

发明人： Shigeyuki Nishimura ,  Fumio Kanamori ,  Masashi Hisamoto

IPC分类号： C07D213/803

CPC分类号： C07D213/80 ,  C07D213/803

摘要： To provide a method for producing a specific nicotinic acid derivative or a salt thereof. A method for producing a nicotinic acid derivative represented by the formula (I): wherein each of X1 and X2 which are independent of each other, is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, a haloalkyl group or a haloalkoxy group; R is an alkyl group; and Hal is a chlorine atom or a bromine atom; or a salt thereof, is provided which comprises reacting a compound represented by the formula (II): is wherein X1, X2 and R are as defined above, or a salt thereof, with a halogenating agent.

摘要翻译： 提供生产特定烟酸衍生物或其盐的方法。 一种制备由式（I）表示的烟酸衍生物的方法：其中X1和X2彼此独立地为氢原子，卤素原子，烷基，烷氧基，卤代烷基或 卤代烷氧基; R是烷基; Hal是氯原子或溴原子; 或其盐，其包括使式（II）表示的化合物：其中X 1，X 2和R如上定义，或其盐与卤化剂反应。