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    BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING
    12.
    发明申请
    BENZOXAZINE DERIVATIVES AND USE IN HAIR DYEING 审中-公开

    公开(公告)号：US20180141922A1

    公开(公告)日：2018-05-24

    申请号：US15502590

    申请日：2015-08-06

    Applicant: L'OREAL

    Inventor： Aziz FADLI

    IPC: C07D265/36 ,  C07D401/06 ,  C07D413/06 ,  A61K8/49 ,  A61Q5/10

    CPC classification number: C07D265/36 ,  A61K8/49 ,  A61Q5/10 ,  C07D401/06 ,  C07D413/06

    Abstract: The invention relates to the use of a compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomers thereof and/or solvates thereof: Formula (I) in which: • R represents a hydrogen atom or a C1-C4 alkyl or C1-C4 hydroxyalkyl radical, preferably a hydrogen atom, • R2, R3, R4 and R5 independently represent: —a hydrogen atom, —a linear C1-C4 or branched C3-C4 alkyl radical, optionally substituted with a hydroxyl radical, • R1 represents a linear C2-C10 or branched C3-C10 alkyl radical, optionally interrupted with one or more heteroatoms chosen from O or S or with one or more groups —NR′, said alkyl radical ending with a group —NX1X2 or —OX3 or a radical chosen from: Formula (II) —X1 and X2 independently denote ◯ a hydrogen atom ◯ a linear C1-C6 alkyl radical or a branched C3-C6 alkyl radical ◯ a linear C1-C6 hydroxyalkyl radical or a branched C3-C6 hydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; said heterocycle possibly being substituted with one or more linear or branched C1-C4 alkyl, C1-C4 hydroxyalkyl or dimethylamino radicals, —X3 denotes a hydrogen atom or a linear C1-C6 or branched C3-C6 alkyl radical, —R′ denotes a hydrogen atom or a linear C1-C4 or branched C3-C4 alkyl radical, for dyeing keratin fibres, especially human keratin fibres such as the hair.

    DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND
    14.
    发明申请
    DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND 有权
    包含1,2,3,4-四氢吡啶并[2,3-B]吡嗪-7-胺化合物的染料组合物

    公开(公告)号：US20160303018A1

    公开(公告)日：2016-10-20

    申请号：US15106083

    申请日：2014-12-19

    Applicant: L'OREAL

    Inventor： Aziz FADLI ,  Stéphane BLAIS

    IPC: A61K8/49 ,  A61Q5/06 ,  C07D471/04

    CPC classification number: A61K8/494 ,  A61K2800/4324 ,  A61Q5/065 ,  A61Q5/10 ,  C07D471/04

    Abstract: The invention relates to a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound of formula (I) below, addition salts thereof, optical isomers, geometrical isomers and tautomers thereof and/or solvates thereof: in which: .R2, R3, R4, R5, and R7 independently represent: a hydrogen or halogen atom; a C1-C4 alkyl radical; a C1-C4 hydroxyalkyl radical; a carboxyl radical; a (C1-C4)alkoxycarbonyl radical; .R1 and R6, which may be identical or different, represent: hydrogen atom; C1-C10 and preferably Ci-C6 alkyl radical, —optionally interrupted with one or more heteroatoms chosen from O and S or with one or more groups —NR and/or —optionally terminating with at least one group —NX1X2 or at least one group —OX3, .X1 and X2 independently denote—a hydrogen atom, a linear C1-C6 alkyl radical, a branched C3-C6 alkyl radical, a linear C1-C6 hydroxyalkyl radical or a branched C3-C6 hydroxyalkyl radical, X1 and X2 may form, with the nitrogen atom that bears them, a saturated or unsaturated 5- to 8-membered heterocycle, in which one of the ring members may be a heteroatom chosen from O, S and N; the said heterocycle possibly being substituted with one or more linear or branched C1-C4 alkyl or C1-C4 hydroxyalkyl radicals, .X3 denotes—a hydrogen atom—a linear C1-C4 or branched C3-C4 alkyl radical, and .R denotes—a hydrogen atom—a linear C1-C4 alkyl radical.

    Abstract translation: 本发明涉及下式（I）的1,2,3,4-四氢吡啶并[2,3-b]吡嗪-7-胺化合物，其加成盐，旋光异构体，几何异构体和其互变异构体和/或溶剂合物 ：其中：R 2，R 3，R 4，R 5和R 7独立地表示：氢或卤素原子; C1-C4烷基; C1-C4羟基烷基; 羧基; （C1-C4）烷氧基羰基; •R 1和R 6可以相同或不同，表示：氢原子; C1-C10和优选C 1 -C 6烷基 - 任选被一个或多个选自O和S的杂原子或与一个或多个基团-NR和/或 - 任选地与至少一个基团-NX 1 X 2或至少一个基团 -O X 3，X 1和X 2独立地表示 - 氢原子，直链C 1 -C 6烷基，支链C 3 -C 6烷基，直链C 1 -C 6羟烷基或支链C 3 -C 6羟烷基，X 1和X 2可以 与带有它们的氮原子一起形成饱和或不饱和的5-至8-元杂环，其中一个环成员可以是选自O，S和N的杂原子; 所述杂环可能被一个或多个直链或支链C 1 -C 4烷基或C 1 -C 4羟基烷基取代，•X3表示 - 氢原子 - 直链C 1 -C 4或支链C 3 -C 4烷基，R表示 - 氢原子 - 直链C 1 -C 4烷基。

    DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE
    16.
    发明申请
    DYE COMPOSITION COMPRISING A PARA-PHENYLENEDIAMINE OXIDATION BASE AND A HETEROCYCLIC OXIDATION BASE 审中-公开

    公开(公告)号：US20190117540A1

    公开(公告)日：2019-04-25

    申请号：US16220343

    申请日：2018-12-14

    Applicant: L'OREAL

    Inventor： Valerie NICOU ,  Isabelle ROLLAT ,  Aziz FADLI

    IPC: A61K8/41 ,  A61Q5/10 ,  A61K8/49

    Abstract: The present invention relates to a composition for dyeing keratin fibres, in particular keratin fibres such as the hair, comprising: a) at least one oxidation base 3-(2,5-diaminophenyl)-1-propanol acid salts thereof or solvates thereof such as hydrates; b) at least one heterocyclic oxidation base; c) at least one coupler; d) optionally at least one fatty substance; e) optionally at least one basifying agent; and f) optionally at least one chemical oxidizing agent. The invention also relates to a process for dyeing keratin fibres such as the hair using the composition of the invention, and to a multi-compartment device for using the composition of the invention.

    USE OF SUBSTITUTED DIHYDROISOQUINOLINIUM SALTS FOR TREATING KERATIN MATERIALS, COMPOSITIONS AND IMPLEMENTATION PROCESSES
    17.
    发明申请
    USE OF SUBSTITUTED DIHYDROISOQUINOLINIUM SALTS FOR TREATING KERATIN MATERIALS, COMPOSITIONS AND IMPLEMENTATION PROCESSES 审中-公开

    公开(公告)号：US20190008742A1

    公开(公告)日：2019-01-10

    申请号：US16064291

    申请日：2016-12-23

    Applicant: L'OREAL

    Inventor： Stéphane SABELLE ,  Aziz FADLI ,  Alexandra CHARRIER

    IPC: A61K8/49 ,  C07D217/10 ,  A61K8/22 ,  C07D217/14 ,  A61Q5/08

    Abstract: The present invention relates to the use of one or more particular dihydroisoquinolinium salts of formula (I) for treating keratin materials, in particular keratin fibres, especially human keratin fibres such as the hair. The invention also relates to a process for treating keratin materials using said salts and optionally one or more chemical oxidizing agents. A subject of the invention is also a composition for lightening keratin materials, comprising one or more dihydroisoquinolinium salts and one or more chemical oxidizing agents. The present invention also relates to one or more particular dihydroisoquinolinium salts and also to compositions containing them, in particular compositions comprising a physiologically acceptable medium.

    DYE COMPOSITION COMPRISING A CATIONIC PARA-AMINOPHENOL OXIDATION BASE
    20.
    发明申请
    DYE COMPOSITION COMPRISING A CATIONIC PARA-AMINOPHENOL OXIDATION BASE 审中-公开
    包含阳离子氨基酚氧化酶基团的染料组合物

    公开(公告)号：US20160374913A1

    公开(公告)日：2016-12-29

    申请号：US15054634

    申请日：2016-02-26

    Applicant: L'OREAL

    Inventor： Aziz FADLI

    IPC: A61K8/41 ,  C07D295/088 ,  C09B69/00 ,  C07C217/84 ,  A61Q5/10 ,  A61K8/49

    CPC classification number: A61K8/415 ,  A61K8/41 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/4926 ,  A61K8/494 ,  A61K8/4946 ,  A61K2800/10 ,  A61K2800/4324 ,  A61K2800/88 ,  A61Q5/10 ,  C07C215/80 ,  C07C217/08 ,  C07C217/84 ,  C07D295/088 ,  C07D295/135 ,  C09B69/001

    Abstract: The present invention relates to a para-aminophenol compound of formula (I), the addition salts thereof with an acid and the solvates thereof: in which: R represents a hydrogen or halogen atom; a C1-C4 alkyl radical; a carboxyl radical or a (C1-C4)alkoxycarbonyl radical; Z1 is an oxygen atom or a group NR2; R2 is a hydrogen atom or a linear or branched C1-C4 alkyl radical, a benzyl radical or an acetyl radical; R1 is a saturated, linear or branched C1-C10 alkyl radical, which is substituted with or interrupted by a cationic radical, optionally interrupted by one or more oxygen atoms and/or by one or more groups NR2, optionally substituted with one or more radicals chosen from hydroxyl, alkoxy or C1-C4 hydroxyalkyl radicals; or R1 is a saturated, unsaturated or aromatic cationic 5- to 8-membered heterocycle optionally substituted with one or more radicals chosen from C1-C4 alkyl, hydroxyl, C1-C4 alkoxy, amino, (C1-C4)alkylamino, di(C1-C4)alkylamino, thio, (C1-C4)alkylthio, carboxyl, (C1-C4)alkylcarbonyl, sulfonyl, amido or C1-C4 hydroxyalkyl radicals; and when Z1 represents NR2 then R1 and R2 may form, together with the nitrogen atom to which they are attached, a saturated or unsaturated cationic 5- to 8-membered heterocycle optionally substituted with one or more radicals chosen from C1-C10 alkyl radicals and hydroxyl, C1-C4 alkoxy, amino, (C1-C4)alkylamino, di(C1-C4)alkylamino, thio, (C1-C4)alkylthio, carboxyl, (C1-C4)alkylcarbonyl, sulfonyl, amido and C1-C4 hydroxyalkyl radicals, it being possible for this heterocycle to contain one or more heteroatoms chosen from N or O, preferably N; or R1 and R2 may form, together with the nitrogen atom to which they are attached, a saturated or unsaturated noncationic 5- to 8-membered heterocycle substituted with a cationic radical and optionally substituted with one or more radicals chosen from C1-C10 alkyl radicals and hydroxyl, C1-C4 alkoxy, amino, (C1-C4)alkylamino, di(C1-C4)alkylamino, thio, (C1-C4)alkylthio, carboxyl, (C1-C4)alkylcarbonyl, sulfonyl, amido and C1-C4 hydroxyalkyl radicals; An− represents an anion or a mixture of anions which are organic or inorganic and are cosmetically acceptable.

    Abstract translation: 本发明涉及式（I）的对氨基苯酚化合物，其与酸及其溶剂化物的加成盐，包含其的染料组合物和染色方法。

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