摘要:
A computer-implemented system and method are disclosed that are capable of refining the order and/or content of a list of items. In one embodiment, user activity associated with each item displayed to users in a given context is monitored, and is used together with item exposure data to generate context-specific item weights. The weights for the same item in different contexts may be different. The selection of items included in a list presented to users, and/or the order in which the items in the list are displayed, may be adjusted over time based upon the relative weights associated with the items.
摘要:
The present invention provides kinase inhibitors of Formula I: wherein W represents inter alia imidazol, oxazol, pyrazol, thiazol as triazol, which are substituted by phenyl or thienyl. The disclosed compounds inhibit p-38 kinase and are useful in the treatment of metastasis or rheumatoid arthritis.