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11.发明授权Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients 有权用于高剂量 - 高溶解度活性成分的剂型，可提供活性成分的即时释放和释放公开(公告)号：US08263125B2
公开(公告)日：2012-09-11
申请号：US11134633
申请日：2005-05-19
CPC分类号： A61K9/209 , A61K9/2077 , A61K9/2081 , A61K31/155 , A61K31/19 , A61K31/22 , A61K31/4025 , A61K31/455 , A61K31/53
摘要： A dosage form comprising of a high dose, high solubility active ingredient as modified release and a low dose active ingredient as immediate release where the weight ratio of immediate release active ingredient and modified release active ingredient is from 1:10 to 1:15000 and the weight of modified release active ingredient per unit is from 500 mg to 1500 mg; a process for preparing the dosage form.
摘要翻译： 一种剂型，其包含高剂量，高溶解度的活性成分作为调节释放剂和低剂量活性成分作为立即释放，其中速释活性成分和释放活性成分的重量比为1:10至1:15000， 每单位改性释放活性成分的重量为500mg至1500mg; 制备剂型的方法。
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公开(公告)号：US07976871B2
公开(公告)日：2011-07-12
申请号：US11134631
申请日：2005-05-19
CPC分类号： A61K31/455 , A61K9/2081 , A61K31/155 , A61K31/19
摘要： A novel modified release dosage form comprising of a high solubility active ingredient, which utilizes dual retard technique to effectively reduce the quantity of release controlling agents. Present invention can optionally comprise additionally another active ingredient as an immediate release form or modified release form. Present invention also relates to a process for preparing the said formulation.
摘要翻译： 一种新的改性释放剂型，其包含高溶解度活性成分，其利用双延迟技术来有效减少释放控制剂的量。 本发明可任选地另外包含作为立即释放形式或改变释放形式的另一活性成分。 本发明还涉及制备所述制剂的方法。
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公开(公告)号：US20060153916A1
公开(公告)日：2006-07-13
申请号：US10522989
申请日：2003-08-01
申请人： Navin Vaya , Rajesh Karan , Sunil Nadkarni , Vinod Qupta
发明人： Navin Vaya , Rajesh Karan , Sunil Nadkarni , Vinod Qupta
IPC分类号： A61K9/26
CPC分类号： A61K9/209 , A61K9/2077 , A61K9/2081 , A61K31/155 , A61K31/19 , A61K31/22 , A61K31/4025 , A61K31/455 , A61K31/53
摘要： A dosage form comprising of a high dose, high solubility active ingredient as modified release and a low dose active ingredient as immediate release where the weight ratio of immediate release active ingredient and modified release active ingredient is from 1:10 to 1:15000 and the weight of modified release active ingredient per unit is from 500 mg to 1500 mg; a process for preparing the dosage form.
摘要翻译： 一种剂型，其包含高剂量，高溶解度的活性成分作为调节释放剂和低剂量活性成分作为立即释放，其中速释活性成分和释放活性成分的重量比为1:10至1:15000， 每单位改性释放活性成分的重量为500mg至1500mg; 制备剂型的方法。
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