公开(公告)号：US6103265A

公开(公告)日：2000-08-15

申请号：US401610

申请日：1999-09-22

申请人： Patrick S.-L. Wong ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Miriam A. Martin ,  Nathan Roth ,  Christopher M. G. Ohms ,  Andrew I. Poutiatine ,  James Horvath

发明人： Patrick S.-L. Wong ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Miriam A. Martin ,  Nathan Roth ,  Christopher M. G. Ohms ,  Andrew I. Poutiatine ,  James Horvath

IPC分类号： A47G21/18 ,  A61J7/00 ,  A61K9/00 ,  A61K9/24

CPC分类号： A61J7/0038 ,  A47G21/183 ,  A61K9/0092

摘要： The present invention is directed to an oral active agent delivery system comprising improved flow controllers. A hollow tubular member (10) containing the active agent formulation and having a fluid passing controller (14) is placed at one end (16) into a fluid and at a second end (18) into a patient's mouth. The active agent is delivered when the patient sips on the end of the chamber. The improved controllers prevent leakage of the active agent formulation.

摘要翻译： 本发明涉及包含改进的流量控制器的口服活性剂递送系统。 含有活性剂制剂并具有流体通过控制器（14）的中空管状构件（10）在一端（16）处放置成流体，并在第二端（18）放置到患者口中。 当患者唾液在腔室的末端时，递送活性剂。 改进的控制器防止活性剂制剂的泄漏。

公开(公告)号：US6096003A

公开(公告)日：2000-08-01

申请号：US950016

申请日：1997-10-14

申请人： Patrick S.-L. Wong ,  James Horvath ,  Radomir N. M. Vukadin ,  Joyce C. Anthony ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Christopher M. G. Ohms

发明人： Patrick S.-L. Wong ,  James Horvath ,  Radomir N. M. Vukadin ,  Joyce C. Anthony ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Christopher M. G. Ohms

IPC分类号： A47G21/18 ,  A61J7/00 ,  A61K9/00 ,  A61M37/00

CPC分类号： A61J7/0038 ,  A47G21/183 ,  A61K9/0092

摘要： The present invention is directed to a closure system for an oral active agent delivery device. The device comprises an elongate tubular member having first and second ends. The closure system includes a deformable closure means adapted to allow delivery of the active agent upon deformation. The closure system prevents spillage and maintains the integrity of the dose within the device. In use, the closure system is deformed and separated from the second end of the tubular member, liquid is drawn up into the first end of the member, and the liquid and active agent are drawn out of the second end of the member and into the patient's mouth.

摘要翻译： 本发明涉及用于口服活性剂递送装置的封闭系统。 该装置包括具有第一端和第二端的细长管状构件。 闭合系统包括适于允许活化剂在变形时输送的可变形闭合装置。 闭合系统防止溢出并维持装置内剂量的完整性。 在使用中，封闭系统变形并与管状构件的第二端分离，液体被拉入构件的第一端，并且液体和活性剂从构件的第二端被拉出并进入 病人的嘴。

公开(公告)号：US5985324A

公开(公告)日：1999-11-16

申请号：US73982

申请日：1998-05-07

申请人： Patrick S.-L. Wong ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Miriam A. Martin ,  Nathan Roth ,  Christopher M. G. Ohms ,  Andrew I. Poutiatine ,  James Horvath

发明人： Patrick S.-L. Wong ,  Vincent J. Ferrari ,  Jeffrey W. Etter ,  Miriam A. Martin ,  Nathan Roth ,  Christopher M. G. Ohms ,  Andrew I. Poutiatine ,  James Horvath

IPC分类号： A47G21/18 ,  A61J7/00 ,  A61K9/00 ,  A61K9/24

CPC分类号： A61J7/0038 ,  A47G21/183 ,  A61K9/0092

摘要： The present invention is directed to an oral active agent delivery system comprising improved flow controllers. A hollow tubular member (10) containing the active agent formulation and having a fluid passing controller (14) is placed at one end (16) into a fluid and at a second end (18) into a patient's mouth. The active agent is delivered when the patient sips on the end of the chamber. The improved controllers prevent leakage of the active agent formulation.

公开(公告)号：US5910321A

公开(公告)日：1999-06-08

申请号：US949753

申请日：1997-10-14

申请人： Patrick S.-L. Wong ,  Nathan Roth ,  Vincent J. Ferrari

发明人： Patrick S.-L. Wong ,  Nathan Roth ,  Vincent J. Ferrari

IPC分类号： A47G21/18 ,  A61J7/00 ,  A61K9/00 ,  A61K9/24

CPC分类号： A61J7/0038 ,  A47G21/183 ,  A61K9/0004

摘要： The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent to a patient. An elongate tubular member having first and second ends comprises first and second flow paths. Either or both of said flow paths contains an active agent. Liquid is drawn up into the first end of the member, and the liquid and active agent is drawn out of the second end of the member and into the patient's mouth.

摘要翻译： 本发明涉及一种口服活性剂递送系统和用于将活性剂的离散单元递送给患者的方法。 具有第一和第二端的细长管状构件包括第一和第二流动路径。 所述流路中的任一个或两者包含活性剂。 液体被吸入构件的第一端，液体和活性剂被从构件的第二端引出并进入患者的口中。

公开(公告)号：US06235111B1

公开(公告)日：2001-05-22

申请号：US09200221

申请日：1998-11-25

申请人： Scott A. Comiso ,  Vincent J. Ferrari ,  Neil J. Bailer ,  Michael D. Damron ,  Nhan Nguyen Thanh Lam

发明人： Scott A. Comiso ,  Vincent J. Ferrari ,  Neil J. Bailer ,  Michael D. Damron ,  Nhan Nguyen Thanh Lam

IPC分类号： B05B700

CPC分类号： C23C22/76 ,  C23C22/00 ,  C23C22/73

摘要： A phosphatizing system for phosphatizing an object including a closed-loop phosphatizing assembly is provided configured to pass a phosphatizing reagent solution over an object during a phosphatizing procedure. The phosphatizing assembly includes a collection compartment in fluid communication with a run-off portion of a subfloor assembly supporting the object for receipt of substantially all the reagent run-off fluids from the subfloor assembly. A storage assembly is configured to pass a rinsing solution over the object to wash the reagent solution therefrom during a finishing rinse procedure performed after the phosphatizing procedure. This storage assembly includes a storage compartment in fluid communication with the run-off portion for receipt of substantially all the rinsing/reagent run-off fluids from the subfloor assembly. A fill pump, in fluid communication between the collection compartment and the storage compartment, is provided to transfer rinsing/reagent run-off fluids collected in the storage compartment to the collection compartment when the reagent solution contained therein drops below a predetermined operational fluid level.

摘要翻译： 提供用于磷化包括闭环磷酸化组件的物体的磷酸化系统，其被配置成在磷酸化过程期间使磷酸化试剂溶液通过物体。 磷酸化组件包括收集室，其与支撑物体的底层地板组件的径流部分流体连通，用于从底层地板组件接收基本上所有的试剂流出液。 存储组件被配置为在磷化过程之后执行的最终漂洗过程中将漂洗溶液通过物体以从其上洗涤试剂溶液。 这种存储组件包括与流出部分流体连通的储存室，用于从底层地板组件接收基本上所有的漂洗/试剂流出液。 提供在收集室和储藏室之间流体连通的填充泵，当收集在其中的试剂溶液低于预定操作液位时，将收集在储存室中的冲洗/试剂流出物流转移到收集室。