专利检索 ap:("President AND Fellows of Harvard College" OR "TRUSTEES OF BOSTON UNIVERSITY" OR "THE BRIGHAM AND WOMEN'S HOSPITAL, INC." OR "Tufts University") AND inv:"Junying Yuan" 第 2 页

11.

发明授权
Inhibitors of cellular necrosis and related methods 有权

公开(公告)号：US10508102B2

公开(公告)日：2019-12-17

申请号：US15897787

申请日：2018-02-15

申请人： President and Fellows of Harvard College , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

发明人： Junying Yuan , Yijun Zhou , Shan Qian , Dawei Ma

IPC分类号： C07D403/06 , C07D233/78 , A61P29/00 , A61P9/10

摘要： A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.

12.

发明申请
INHIBITORS OF CELLULAR NECROSIS AND RELATED METHODS 审中-公开

公开(公告)号：US20190023690A1

公开(公告)日：2019-01-24

申请号：US15897787

申请日：2018-02-15

申请人： President and Fellows of Harvard College , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

发明人： Junying Yuan , Yijun Zhou , Shan Qian , Dawei Ma

IPC分类号： C07D403/06 , A61P29/00 , C07D233/78 , A61P9/10

CPC分类号： C07D403/06 , A61P9/10 , A61P29/00 , C07D233/78

摘要： A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.

13.

发明授权
Inhibitors of cellular necrosis and related methods 有权

公开(公告)号：US09944628B2

公开(公告)日：2018-04-17

申请号：US14966968

申请日：2015-12-11

申请人： President and Fellows of Harvard College , Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences

发明人： Junying Yuan , Yijun Zhou , Shan Qian , Dawei Ma

IPC分类号： C07D233/78 , C07D403/06

CPC分类号： C07D403/06 , A61P9/10 , A61P29/00 , C07D233/78

摘要： A compound having the following structure (I): or a pharmaceutically acceptable salt, prodrug, stereoisomer or tautomer thereof, is provided. Related compounds, methods for preparation of the same and uses of the compounds for treatment of various indications, including treatment of necrotic cell diseases and/or inflammation, are also provided.