公开(公告)号：US20210147947A1

公开(公告)日：2021-05-20

申请号：US17103544

申请日：2020-11-24

Applicant: Quest Diagnostics Investments LLC

Inventor： Kevin Qu ,  Anthony Sferruzza ,  Ke Zhang ,  Yan Liu ,  Renius Owen

IPC: C12Q1/6886

Abstract: Provided herein are methods for miRNA profiling for the diagnosis, prognosis, and management of melanoma and differentiation of melanoma from nevi.

公开(公告)号：US10851424B2

公开(公告)日：2020-12-01

申请号：US15999033

申请日：2018-08-20

Applicant: Quest Diagnostics Investments LLC

Inventor： Kevin Qu ,  Anthony Sferruzza ,  Ke Zhang ,  Yan Liu ,  Renius Owen

IPC: C12Q1/6886

Abstract: Provided herein are methods for miRNA profiling for the diagnosis, prognosis, and management of melanoma and differentiation of melanoma from nevi.

公开(公告)号：US20190177805A1

公开(公告)日：2019-06-13

申请号：US16324365

申请日：2017-08-09

Applicant: Quest Diagnostics Investments LLC

Inventor： Kevin Qu ,  Feras Hantash ,  Amber Donahue

IPC: C12Q1/6886 ,  C12Q1/6827 ,  C12Q1/6816

Abstract: The present technology relates to methods for excluding Lynch syndrome as a possible diagnosis in patients suffering from colorectal cancers or endometrial cancers. These methods are based on detecting the methylation status of the MLH1 promoter ‘C’ region in colorectal and endometrial cancer patients using an improved and highly sensitive methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA) assay.